ENZYME - Browse Classes and Subclasses

The following list contains the definitions of enzyme classes, subclasses and sub-subclasses. If you click on one of the following lines, you will get a list of all enzymes in the corresponding classes, with the possibility to obtain a list of all corresponding UniProtKB/Swiss-Prot entries.

A single file containing all enzyme entries can be found at https://ftp.expasy.org/databases/enzyme/enzyme.dat.

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1. -. -.-  Oxidoreductases.
1. 1. -.-   Acting on the CH-OH group of donors.
1. 2. -.-   Acting on the aldehyde or oxo group of donors.
1. 3. -.-   Acting on the CH-CH group of donors.
1. 4. -.-   Acting on the CH-NH2 group of donors.
1. 5. -.-   Acting on the CH-NH group of donors.
1. 6. -.-   Acting on NADH or NADPH.
1. 7. -.-   Acting on other nitrogenous compounds as donors.
1. 8. -.-   Acting on a sulfur group of donors.
1. 9. -.-   Acting on a heme group of donors.
1.10. -.-   Acting on diphenols and related substances as donors.
1.11. -.-   Acting on a peroxide as acceptor.
1.12. -.-   Acting on hydrogen as donors.
1.13. -.-   Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2.
1.14. -.-   Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2.
1.15. -.-   Acting on superoxide as acceptor.
1.16. -.-   Oxidizing metal ions.
1.17. -.-   Acting on CH or CH2 groups.
1.18. -.-   Acting on iron-sulfur proteins as donors.
1.19. -.-   Acting on reduced flavodoxin as donor.
1.20. -.-   Acting on phosphorus or arsenic in donors.
1.21. -.-   Catalyzing the reaction X-H + Y-H = 'X-Y'.
1.22. -.-   Acting on halogen in donors.
1.23. -.-   Reducing C-O-C group as acceptor.
1.97. -.-   Other oxidoreductases.
1.98. -.-   Enzymes using H2 as reductant.
1.99. -.-   Other enzymes using O2 as oxidant.
2. -. -.-  Transferases.
2. 1. -.-   Transferring one-carbon groups.
2. 2. -.-   Transferring aldehyde or ketonic groups.
2. 3. -.-   Acyltransferases.
2. 4. -.-   Glycosyltransferases.
2. 5. -.-   Transferring alkyl or aryl groups, other than methyl groups.
2. 6. -.-   Transferring nitrogenous groups.
2. 7. -.-   Transferring phosphorus-containing groups.
2. 8. -.-   Transferring sulfur-containing groups.
2. 9. -.-   Transferring selenium-containing groups.
2.10. -.-   Transferring molybdenum- or tungsten-containing groups.
3. -. -.-  Hydrolases.
3. 1. -.-   Acting on ester bonds.
3. 2. -.-   Glycosylases.
3. 3. -.-   Acting on ether bonds.
3. 4. -.-   Acting on peptide bonds (peptidases).
3. 5. -.-   Acting on carbon-nitrogen bonds, other than peptide bonds.
3. 6. -.-   Acting on acid anhydrides.
3. 7. -.-   Acting on carbon-carbon bonds.
3. 8. -.-   Acting on halide bonds.
3. 9. -.-   Acting on phosphorus-nitrogen bonds.
3.10. -.-   Acting on sulfur-nitrogen bonds.
3.11. -.-   Acting on carbon-phosphorus bonds.
3.12. -.-   Acting on sulfur-sulfur bonds.
3.13. -.-   Acting on carbon-sulfur bonds.
4. -. -.-  Lyases.
4. 1. -.-   Carbon-carbon lyases.
4. 2. -.-   Carbon-oxygen lyases.
4. 3. -.-   Carbon-nitrogen lyases.
4. 4. -.-   Carbon-sulfur lyases.
4. 5. -.-   Carbon-halide lyases.
4. 6. -.-   Phosphorus-oxygen lyases.
4. 7. -.-   Carbon-phosphorus lyases.
4. 8. -.-   Nitrogen-oxygen lyases.
4.98. -.-   ATP-independent chelatases.
4.99. -.-   Other lyases.
5. -. -.-  Isomerases.
5. 1. -.-   Racemases and epimerases.
5. 2. -.-   Cis-trans-isomerases.
5. 3. -.-   Intramolecular oxidoreductases.
5. 4. -.-   Intramolecular transferases.
5. 5. -.-   Intramolecular lyases.
5. 6. -.-   Isomerases altering macromolecular conformation.
5.99. -.-   Other isomerases.
6. -. -.-  Ligases.
6. 1. -.-   Forming carbon-oxygen bonds.
6. 2. -.-   Forming carbon-sulfur bonds.
6. 3. -.-   Forming carbon-nitrogen bonds.
6. 4. -.-   Forming carbon-carbon bonds.
6. 5. -.-   Forming phosphoric ester bonds.
6. 6. -.-   Forming nitrogen-metal bonds.
6. 7. -.-   Forming nitrogen-nitrogen bonds.
7. -. -.-  Translocases.
7. 1. -.-   Catalysing the translocation of hydrons.
7. 2. -.-   Catalysing the translocation of inorganic cations.
7. 3. -.-   Catalysing the translocation of inorganic anions and their chelates.
7. 4. -.-   Catalysing the translocation amino acids and peptides.
7. 5. -.-   Catalysing the translocation carbohydrates and their derivatives.
7. 6. -.-   Catalysing the translocation of other compounds.