What a Friend We Have in Jesus

• Washington Phillips, as "Jesus Is My Friend" (1928, Columbia Records)^[5][6]
• Bing Crosby (1951, Beloved Hymns)
• Tennessee Ernie Ford (1958, Nearer the Cross, Capitol Records)
• Rosemary Clooney (1959, Hymns from the Heart, MGM Records)
• The Stanley Brothers (1960)
• Reno & Smiley and the Tennessee Cut-Ups (1963)
• Ella Fitzgerald with the Ralph Carmichael Choir (1967, Brighten the Corner)
• Thurl Ravenscroft (1970, Great Hymns In Story and Song)
• Aretha Franklin (1972, Amazing Grace)
• Alan Price (1973, O Lucky Man! as "Changes")
• Mahalia Jackson Gospels, Spirituals, and Hymns.
• Ike & Tina Turner (1974, The Gospel According to Ike & Tina)
• Lester Flatt & and the Nashville Grass (1975), the LP Flatt Gospel. Also performed by Flatt & Scruggs while Flatt and Earl Scruggs played together.
• Bill Monroe (Bear Family (German) BCD-16639 My Last Days On Earth 1981-1994
• Wade and Julia Mainer with unknown musicians (1989)
• Glen Campbell (1989, Favorite Hymns)
• Driving Miss Daisy (1989) sung at Little Friendship Baptist Church in Atlanta, Georgia
• The John Tesh Project (2000, Pure Hymns)^[7]
• Amy Grant recorded it as part of the medley "What a Friend We Have in Jesus/Old Rugged Cross/How Great Thou Art" on her 2002 studio album Legacy... Hymns and Faith, and later included on her 2015 compilation album Be Still and Know... Hymns & Faith.
• Alan Jackson (2006, Precious Memories)
• Brad Paisley (2008, Play)
• Ronnie Milsap (2009, Then Sings My Soul)
• Hugh Laurie (2013, Didn't It Rain as "Changes" by Alan Price)
• Monty Alexander (2013, Uplift 2)^[8]
• Perkins Twins (2018)
• William Bolcom composed a setting of the hymn in 1979.^[9]

In East Africa, the hymn's title is translated as "Yesu Kwetu ni Rafiki" in Swahili.

In Kimeru, a local dialect in Kenya, the song was translated to Jesu ni Mucore wetu and is hymn no 59 in the iuku ria ndwimbo. In Kikuyu, the hymn was translated to: Ti itheru twi Murata.

In Kalenjin hymns commonly known as Tienwogik Che Kilosune Jehovah, the song is number 34, Choruenyu Kiptaiyat Jesu.

In Basaa, a local language in Cameroon, the hymn is translated as "Wanda Djem Djol Die Le Yesu".

In the Dholuo hymns of Kenya, it is translated as "Yesu Kristo en Osiepwa."

In Japan, the hymn's title was originally translated as "Itsukushimi Fukaki" (いつくしみ深き, lit. "Merciful"),^[10] by which it is best known. In 1910, Daisui Sugitani rewrote the lyrics in Japanese and changed the title to "Hoshi no Yo" (星の界, lit. "World of Stars"). Another version was written by Ryūkō Kawaji with the title "Hoshi no Sekai" (星の世界, lit. "World of Stars"). It is also known by the title "Tsumitoga o Ninou" (つみとがをにのう, lit. "To Bear Sin"). The hymn is popular at wedding ceremonies in Japan.^[11] Both hymn instrumentals of "Hoshi no Sekai" and "Itsukushimi Fukaki" are used as background music for Key's 2004 visual novel Planetarian: The Reverie of a Little Planet, arranged by Magome Togoshi. The hymn was also used as a recurring motif in the 2006 film Memories of Matsuko. The melody also appears as an instrumental during certain episodes of the 2021 anime series Taisho Otome Fairy Tale.

In Indonesia, the hymn is known as "Yesus Kawan yang Sejati" and is sung in Indonesian or Batak (the indigenous language of North Sumatra) in Manado, Maluccan, and Protestant churches (around 6% of the population). Statistically, most Indonesians are Muslim (around 76%), but native religion elements have up to 90% of the total population and consequently the hymn is widely known only among musicians, scholars, and Indonesia's Christian community. Prior to when Suharto seized power in 1967, though, the same music was adopted for a popular patriotic song titled "Ibu Pertiwi".

In Hindi, the hymn is a very important song and is sung as "Yeshu kaisa dost pyara". In Marathi, the hymn has been translated as "Kon Mitra Yeshuwani" By Mary Bessel. The song is common during solemn services (Passion week and burial). In Malayalam, the hymn as "Enthu Nallore sakhi Yesu" is sung to comfort and as an invitation to Christ.^[12] This hymn had been translated into Telugu and is sung during occasions as a song of comfort and solace. It is translated as "Preethi gala mana Yesu" and is listed in the Andhra Kraisthava Keerthanalu (Andhra Christian hymnals) as hymn No. 407.^[13]

In India, the hymn sung in Konkani, "Dulob Jezu", was translated by Felix Paul Noronha of Mangalore.

In South Korea, the hymn is translated as the title of "The Savior who took our burden of sins". The hymn was first introduced to South Korea by Oriental Mission Society, which is the previous organization of Korea Evangelical Holiness Church in 1919. This hymn has been sung by the church of evangelical denomination in common for a century. The remake version has been also made through contemporary Christian music.

Parody versions have included the First World War soldiers' song "When this lousy war is over",^[14] the IWW song "Dump the Bosses off your Back",^[15] and the Pete Seeger anti-war song "What a Friend We Have in Congress".^[16]

This tune is used as a tune for an Indonesian patriotic song called "Ibu Pertiwi" which was composed in 1908 by Kamsidi Samsuddin. It was also used as the theme song of 2019 film adaptation of This Earth of Mankind, performed by Iwan Fals, Once and Fiersa Besari.^[17]

Alan Price used the melody as the basis of his song "Changes," from the 1973 film O Lucky Man! and its soundtrack album, which was reused in a Volkswagen commercial of the same name with Paula Hamilton in the 1980s. In 1989, the song reached number 54 on the UK charts and number 29 on the German charts. In 2013, Hugh Laurie covered the song on his album Didn't It Rain.

• Rise Up Singing, page 98
• The Lutheran Hymnal, hymn #457

• "What a Friend We Have in Jesus". Silver wings : a collection of entirely new Sunday school music. Boston : Oliver Ditson & Co. [etc.] 1870. Retrieved 2020-07-05.
• Piano score (pdf) at Timeless Truths