Piezo-type mechanosensitive ion channel component 2 is a protein that in humans is encoded by the PIEZO2 gene .[ 5] [ 6]
PIEZO2 Identifiers Aliases PIEZO2 External IDs OMIM : 613629 ; MGI : 1918781 ; HomoloGene : 49695 ; GeneCards : PIEZO2 ; OMA :PIEZO2 - orthologs Wikidata
Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains . 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The PIEZO2 protein has a role in rapidly adapting mechanically activated (MA) currents in somatosensory neurons.[ 7] [ 8]
PIEZO2 is typically found in cell types that respond to physical touch, such as Merkel cells ,[ 9] [ 10]
^ a b c GRCh38: Ensembl release 89: ENSG00000154864 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041482 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^
"Entrez Gene: Piezo-type mechanosensitive ion channel component 2" . Retrieved 2013-08-06 .
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This article incorporates text from the United States National Library of Medicine , which is in the public domain .
