FOXS1

FOXS1
Identifiers
Aliases	FOXS1, FKHL18, FREAC10, forkhead box S1
External IDs	OMIM: 602939; MGI: 95546; HomoloGene: 20871; GeneCards: FOXS1; OMA:FOXS1 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	31,845,604 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	152,775,128 bp
RNA expression pattern
	Top expressed in
	right coronary artery; ; left coronary artery; ; ascending aorta; ; testicle; ; Descending thoracic aorta; ; popliteal artery; ; tibial arteries; ; apex of heart; ; tibial nerve; ; right auricle;
	Top expressed in
	external carotid artery; ; internal carotid artery; ; embryo; ; sciatic nerve; ; muscle of thigh; ; Gonadal ridge; ; right kidney; ; stroma of bone marrow; ; spermatocyte; ; endothelial cell of lymphatic vessel;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	blood vessel development; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; negative regulation of DNA-binding transcription factor activity; neuromuscular process controlling balance; transcription, DNA-templated; positive regulation of multicellular organism growth; negative regulation of transcription by RNA polymerase II; anatomical structure morphogenesis; cell differentiation; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	2307
	14239
	ENSG00000179772
	ENSMUSG00000074676
	O43638
	Q61574
	NM_004118
	NM_010226
	NP_004109
	NP_034356
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box S1 is a protein that in humans is encoded by the FOXS1 gene. ^[5]

Function

The forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a forkhead domain and is found predominantly in aorta and kidney. The function of the encoded protein is unknown. [provided by RefSeq, Jul 2008].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000179772 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000074676 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Forkhead box S1". Retrieved 2018-01-07.

FOXS1

Function

References

Further reading