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Curtis Huttenhower

Curtis Huttenhower is a Professor of Computational Biology and Bioinformatics in the Department of Biostatistics, School of Public Health, Harvard University.[7][10][11][12]

Curtis Huttenhower
Born (1981-06-18) June 18, 1981 (age 43)[9]
Alma mater
AwardsOverton Prize (2015)[1]
Scientific career
Fields
InstitutionsHarvard University
ThesisAnalysis of large genomic data collections (2009)
Doctoral advisorOlga Troyanskaya[8]
Websitehuttenhower.sph.harvard.edu

Education

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Huttenhower gained his BS from the Rose-Hulman Institute of Technology in 2000, where he majored in computer science, chemistry and mathematics. He then spent two years as a software developer for Microsoft, working on the Microsoft Natural Language Development Platform. Huttenhower gained his MS in computational linguistics from Carnegie Mellon University in 2003, where he studied with Dannie Durand and Eric Nyberg. In 2003, Huttenhower moved to Princeton University where he was awarded a PhD in 2008 for research in genomics supervised by Olga Troyanskaya. His PhD thesis was titled Analysis of large genomic data collections.[1][13]

Research

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Huttenhower joined the Harvard T.H. Chan School of Public Health in 2009 as an assistant professor of computational biology and bioinformatics,[1] becoming an associate professor in 2013.[8] Huttenhower's lab worked extensively with the NIH Human Microbiome Project (HMP) to identify and characterise the microorganisms found in association with both healthy and diseased humans.[2][3][4] As of 2015, he co-leads one of the follow-up 'HMP2' Centers for Characterizing the Gut Microbial Ecosystem in Inflammatory Bowel Disease.[14]

Awards and honors

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Huttenhower received an NSF CAREER award in 2010 for his research on microbial communities[8][15] and was awarded a Presidential Early Career Award for Scientists and Engineers in 2012.[16] In 2015, Huttenhower was awarded the Overton Prize[1] from the International Society for Computational Biology. His PhD supervisor Olga Troyanskaya had been awarded the same prize in 2011.[17] Huttenhower is also a member of the editorial boards for the academic journals Genome Biology, Microbiome and BMC Bioinformatics.[18] [19] [20]

Select publications

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  • M. Ross; M. Nathalia Garcia; Vivien Bonazzi; et al. (14 June 2012). "Structure, function and diversity of the healthy human microbiome". Nature. 486 (7402): 207–14. Bibcode:2012Natur.486..207T. doi:10.1038/NATURE11234. ISSN 1476-4687. PMC 3564958. PMID 22699609. Wikidata Q24626370.
  • Nicola Segata; Jacques Izard; Levi Waldron; Dirk Gevers; Larisa Miropolsky; Wendy S Garrett; Curtis Huttenhower (24 June 2011). "Metagenomic biomarker discovery and explanation". Genome Biology. 12 (6): R60. doi:10.1186/GB-2011-12-6-R60. ISSN 1465-6906. PMC 3218848. PMID 21702898. Wikidata Q35557728.}}
  • Morgan Langille; Jesse Zaneveld; J Gregory Caporaso; et al. (25 August 2013). "Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences". Nature Biotechnology. 31 (9): 814–821. doi:10.1038/NBT.2676. ISSN 1087-0156. PMC 3819121. PMID 23975157. Wikidata Q29615050.

References

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  1. ^ a b c d Fogg, Christiana N.; Kovats, Diane E. (2015). "2015 ISCB Overton Prize Awarded to Curtis Huttenhower". PLOS Computational Biology. 11 (6): e1004319. Bibcode:2015PLSCB..11E4319F. doi:10.1371/journal.pcbi.1004319. ISSN 1553-7358. PMC 4466272. PMID 26067840. Open access icon 
  2. ^ a b Human Microbiome Project Consortium; Gevers, Dirk; Knight, Rob; Abubucker, Sahar; Badger, Jonathan H.; Chinwalla, Asif T.; Creasy, Heather H.; Earl, Ashlee M.; Fitzgerald, Michael G.; Fulton, Robert S.; Giglio, Michelle G.; Hallsworth-Pepin, Kymberlie; Lobos, Elizabeth A.; Madupu, Ramana; Magrini, Vincent; Martin, John C.; Mitreva, Makedonka; Muzny, Donna M.; Sodergren, Erica J.; Versalovic, James; Wollam, Aye M.; Worley, Kim C.; Wortman, Jennifer R.; Young, Sarah K.; Zeng, Qiandong; Aagaard, Kjersti M.; Abolude, Olukemi O.; Allen-Vercoe, Emma; Alm, Eric J.; et al. (2012). "Structure, function and diversity of the healthy human microbiome". Nature. 486 (7402): 207–14. Bibcode:2012Natur.486..207T. doi:10.1038/nature11234. PMC 3564958. PMID 22699609.
  3. ^ a b Human Microbiome Project Consortium; Nelson, Karen E.; Pop, Mihai; Creasy, Heather H.; Giglio, Michelle G.; Huttenhower, Curtis; Gevers, Dirk; Petrosino, Joseph F.; Abubucker, Sahar; Badger, Jonathan H.; Chinwalla, Asif T.; Earl, Ashlee M.; Fitzgerald, Michael G.; Fulton, Robert S.; Hallsworth-Pepin, Kymberlie; Lobos, Elizabeth A.; Madupu, Ramana; Magrini, Vincent; Martin, John C.; Mitreva, Makedonka; Muzny, Donna M.; Sodergren, Erica J.; Versalovic, James; Wollam, Aye M.; Worley, Kim C.; Wortman, Jennifer R.; Young, Sarah K.; Zeng, Qiandong; Aagaard, Kjersti M.; et al. (2012). "A framework for human microbiome research". Nature. 486 (7402): 215–21. Bibcode:2012Natur.486..215T. doi:10.1038/nature11209. PMC 3377744. PMID 22699610.
  4. ^ a b Abubucker, S; Segata, N; Goll, J; Schubert, A. M.; Izard, J; Cantarel, B. L.; Rodriguez-Mueller, B; Zucker, J; Thiagarajan, M; Henrissat, B; White, O; Kelley, S. T.; Methé, B; Schloss, P. D.; Gevers, D; Mitreva, M; Huttenhower, C (2012). "Metabolic reconstruction for metagenomic data and its application to the human microbiome". PLOS Computational Biology. 8 (6): e1002358. Bibcode:2012PLSCB...8E2358A. doi:10.1371/journal.pcbi.1002358. PMC 3374609. PMID 22719234.
  5. ^ Huttenhower, C; Mutungu, K. T.; Indik, N; Yang, W; Schroeder, M; Forman, J. J.; Troyanskaya, O. G.; Coller, H. A. (2009). "Detailing regulatory networks through large scale data integration". Bioinformatics. 25 (24): 3267–74. doi:10.1093/bioinformatics/btp588. PMC 2788929. PMID 19825796.
  6. ^ Huttenhower, C; Hofmann, O (2010). "A quick guide to large-scale genomic data mining". PLOS Computational Biology. 6 (5): e1000779. Bibcode:2010PLSCB...6E0779H. doi:10.1371/journal.pcbi.1000779. PMC 2877728. PMID 20523745.
  7. ^ a b Curtis Huttenhower publications indexed by Google Scholar
  8. ^ a b c "Curtis Huttenhower CV" (PDF). huttenhower.org. 2015. Archived from the original (PDF) on 2015-03-02.
  9. ^ Huttenhower, Curtis, 1981-, Library of Congress
  10. ^ Chi, A; Huttenhower, C; Geer, L. Y.; Coon, J. J.; Syka, J. E.; Bai, D. L.; Shabanowitz, J; Burke, D. J.; Troyanskaya, O. G.; Hunt, D. F. (2007). "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry". Proceedings of the National Academy of Sciences. 104 (7): 2193–8. Bibcode:2007PNAS..104.2193C. doi:10.1073/pnas.0607084104. PMC 1892997. PMID 17287358.
  11. ^ Huttenhower, C; Knight, R; Brown, C. T.; Caporaso, J. G.; Clemente, J. C.; Gevers, D; Franzosa, E. A.; Kelley, S. T.; Knights, D; Ley, R. E.; Mahurkar, A; Ravel, J; Scientists for Advancement of Microbiome Research; White, O (2014). "Advancing the microbiome research community". Cell. 159 (2): 227–30. doi:10.1016/j.cell.2014.09.022. PMC 4221798. PMID 25303518.
  12. ^ Curtis Huttenhower's publications indexed by the Scopus bibliographic database. (subscription required)
  13. ^ Huttenhower, Curtis (2009). Analysis of large genomic data collections (PhD thesis). Princeton University. OCLC 298182845.
  14. ^ "Home - Curtis Huttenhower - Harvard T.H. Chan School of Public Health". www.hsph.harvard.edu. Retrieved 4 August 2015.
  15. ^ "Curtis Huttenhower wins top junior faculty award in bioinformatics". hsph.harvard.edu. 2015-02-11. Retrieved 4 August 2015.
  16. ^ "President Obama Honors Early Career Scientists and Engineers - NSF - National Science Foundation". www.nsf.gov. Retrieved 4 August 2015.
  17. ^ Mullins, Justin; Morrison McKay, BJ (2 June 2011). "International Society for Computational Biology Honors Michael Ashburner and Olga Troyanskaya with Top Bioinformatics/Computational Biology Awards for 2011". PLOS Computational Biology. 7 (6): e1002081. Bibcode:2011PLSCB...7E2081M. doi:10.1371/journal.pcbi.1002081. PMC 3107244.
  18. ^ "Genome Biology - Editorial Board". www.genomebiology.com. Retrieved 4 August 2015.
  19. ^ "Microbiome - Editorial Board". www.microbiomejournal.com. Retrieved 4 August 2015.
  20. ^ "BMC Bioinformatics - Editorial Board". www.biomedcentral.com. Retrieved 4 August 2015.
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