Carbutamide

Carbutamide
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	A10BB06 (WHO) ;
Identifiers
	IUPAC name 4-amino-N-(butylcarbamoyl)benzenesulfonamide;
CAS Number	339-43-5 ;
PubChem CID	9564;
ChemSpider	9189 ;
UNII	E3K8P4869P;
ChEMBL	ChEMBL448570 ;
CompTox Dashboard (EPA)	DTXSID8022741 ;
ECHA InfoCard	100.005.841
Chemical and physical data
Formula	C11H17N3O3S
Molar mass	271.33 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=S(=O)(c1ccc(N)cc1)NC(=O)NCCCC;
	InChI InChI=1S/C11H17N3O3S/c1-2-3-8-13-11(15)14-18(16,17)10-6-4-9(12)5-7-10/h4-7H,2-3,8,12H2,1H3,(H2,13,14,15) ; Key:VDTNNGKXZGSZIP-UHFFFAOYSA-N ;
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Carbutamide (brand name Glucidoral) is an anti-diabetic drug of the sulfonylurea class, developed by Servier.

It is classified as first-generation.^[1]

It was patented in 1953 and approved for medical use in 1956.^[2]

References

^ Ballagi-Pordány G, Köszeghy A, Koltai MZ, Aranyi Z, Pogátsa G (January 1990). "Divergent cardiac effects of the first and second generation hypoglycemic sulfonylurea compounds". Diabetes Research and Clinical Practice. 8 (2): 109–114. doi:10.1016/0168-8227(90)90020-T. PMID 2106423.
^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 449. ISBN 9783527607495.

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Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	A10BB06 (WHO)
Identifiers
IUPAC name 4-amino-N-(butylcarbamoyl)benzenesulfonamide
CAS Number	339-43-5^Y
PubChem CID	9564
ChemSpider	9189^N
UNII	E3K8P4869P
ChEMBL	ChEMBL448570^Y
CompTox Dashboard (EPA)	DTXSID8022741
ECHA InfoCard	100.005.841
Chemical and physical data
Formula	C₁₁H₁₇N₃O₃S
Molar mass	271.33 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=S(=O)(c1ccc(N)cc1)NC(=O)NCCCC
InChI InChI=1S/C11H17N3O3S/c1-2-3-8-13-11(15)14-18(16,17)10-6-4-9(12)5-7-10/h4-7H,2-3,8,12H2,1H3,(H2,13,14,15)^N Key:VDTNNGKXZGSZIP-UHFFFAOYSA-N^N
^NY (what is this?) (verify)