4-HO-PiPT

4-HO-PiPT
Identifiers
	IUPAC name 3-{2-[(propan-2-yl)(propyl)amino]ethyl}-1H-indol-4-ol;
PubChem CID	166468747;
Chemical and physical data
Formula	C16H24N2O
Molar mass	260.381 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)N(CCC)CCc1c[NH]c2cccc(O)c21;
	InChI InChI=1S/C16H24N2O/c1-4-9-18(12(2)3)10-8-13-11-17-14-6-5-7-15(19)16(13)14/h5-7,11-12,17,19H,4,8-10H2,1-3H3; Key:CUTUPKOZXNFVHK-UHFFFAOYSA-N;

4-Hydroxy-N-propyl-N-isopropyltryptamine (4-HO-PiPT, Piprocin) is a substituted tryptamine derivative which is claimed to have psychedelic effects.^[1] It acts as a 5-HT_2A receptor agonist, with an EC₅₀ of 13.8 nM and an efficacy of 104.8% (vs 5-HT),^[2] and has been sold as a designer drug, first being identified in 2021 in British Columbia, Canada.^[3]

References

^ Morrison J. Glycosylated psilocin derivatives and methods of use. WO 2024/042239A1
^ Banister S, Jorgensen W, Jinlong T. Compounds. Patent WO 2023/115167
^ Knill A, Tobias S, Matthews J, Ti L (June 2022). A Report on British Columbia's Unregulated Drug Supply. Drug checking trends across British Columbia, January to December 2021 (PDF). British Columbia Centre on Substance Use (Report).

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.

[1] Morrison J. Glycosylated psilocin derivatives and methods of use. WO 2024/042239A1

[2] Banister S, Jorgensen W, Jinlong T. Compounds. Patent WO 2023/115167

[3] Knill A, Tobias S, Matthews J, Ti L (June 2022). A Report on British Columbia's Unregulated Drug Supply. Drug checking trends across British Columbia, January to December 2021 (PDF). British Columbia Centre on Substance Use (Report).

[1]

[2]

[3]

Identifiers

IUPAC name 3-{2-[(propan-2-yl)(propyl)amino]ethyl}-1H-indol-4-ol
PubChem CID	166468747
Chemical and physical data
Formula	C₁₆H₂₄N₂O
Molar mass	260.381 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)N(CCC)CCc1c[NH]c2cccc(O)c21
InChI InChI=1S/C16H24N2O/c1-4-9-18(12(2)3)10-8-13-11-17-14-6-5-7-15(19)16(13)14/h5-7,11-12,17,19H,4,8-10H2,1-3H3 Key:CUTUPKOZXNFVHK-UHFFFAOYSA-N

4-HO-PiPT

See also

References