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Chemical compound
Pharmaceutical compound
AB-PICA Legal status
N -[(1S )-1-(aminocarbonyl)-2-methylpropyl]-1-pentyl-1H-indole-3-carboxamide
CAS Number UNII Formula C 19 H 27 N 3 O 2 Molar mass −1 3D model (JSmol )
O=C(N[C@H](C(N)=O)C(C)C)C1=CN(CCCCC)C2=CC=CC=C21
InChI=1S/C19H27N3O2/c1-4-5-8-11-22-12-15(14-9-6-7-10-16(14)22)19(24)21-17(13(2)3)18(20)23/h6-7,9-10,12-13,17H,4-5,8,11H2,1-3H3,(H2,20,23)(H,21,24)/t17-/m0/s1
Key:GOLDNQQANLFVSP-KRWDZBQOSA-N
AB-PICA is a potent agonist for the CB1 receptor (EC50 = 12 nM) and CB2 receptor (EC50 = 12 nM).[ 1]
^ Banister SD, Moir M, Stuart J, Kevin RC, Wood KE, Longworth M, et al. (September 2015). "Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA". ACS Chemical Neuroscience . 6 (9): 1546–59. doi :10.1021/acschemneuro.5b00112 . PMID 26134475 .
Phytocannabinoids comparison )
Cannabibutols Cannabichromenes Cannabicyclols Cannabidiols Cannabielsoins Cannabigerols Cannabiphorols Cannabinols Cannabitriols Cannabivarins Delta-8-tetrahydrocannabinols Delta-9-tetrahydrocannabinols Delta-10-Tetrahydrocannabinols Miscellaneous cannabinoids Active metabolites
Endocannabinoids Synthetic
Classical cannabinoids Non-classical Adamantoylindoles Benzimidazoles Benzoylindoles Cyclohexylphenols Eicosanoids Indazole-3- Indole-3-carboxamides Indole-3-carboxylates Naphthoylindazoles Naphthoylindoles Naphthoylpyrroles Naphthylmethylindenes Naphthylmethylindoles Phenylacetylindoles Pyrazolecarboxamides Tetramethylcyclo- Tetramethylcyclo- Others
Allosteric CBR Tooltip Cannabinoid receptor ligands Endocannabinoid (inactivation inhibitors) Anticannabinoids (antagonists/inverse
