Vibrionaceae

Vibrionaceae
Vibrio cholerae
Scientific classification
Domain:	Bacteria
Phylum:	Pseudomonadota
Class:	Gammaproteobacteria
Order:	Vibrionales Garrity and Holt 2001
Family:	Vibrionaceae Véron 1965 (Approved Lists 1980)
Genera
Aliivibrio Urbanczyk et al. 2007 Catenococcus Sorokin 1994 "Corallibacterium" Hettiarachchi et al. 2018 Echinimonas Nedashkovskaya et al. 2013 Enterovibrio Thompson et al. 2002 Grimontia Thompson et al. 2003 Listonella MacDonell and Colwell 1986 Paraphotobacterium Huang et al. 2016 Photobacterium Beijerinck 1889 (Approved Lists 1980) "Candidatus Photodesmus" Hendry and Dunlap 2011 Salinivibrio Mellado et al. 1996 Thaumasiovibrio Amin et al. 2018 Veronia Gomez-Gil et al. 2022 Vibrio Pacini 1854 (Approved Lists 1980)

The Vibrionaceae are a family of Pseudomonadota given their own order, Vibrionales. Inhabitants of fresh or salt water, several species are pathogenic, including the type species Vibrio cholerae, which is the agent responsible for cholera. Most bioluminescent bacteria belong to this family, and are typically found as symbionts of deep-sea animals.^[1]

Vibrionaceae are Gram-negative organisms and facultative anaerobes, capable of fermentation. They contain oxidase and have one or more flagella, which are generally polar. Originally, these characteristics defined the family, which was divided into four genera. Two of these, Vibrio and Photobacterium, correspond to the modern group, although several new genera have been defined. Genetic studies have shown the other two original members—Aeromonas and Plesiomonas—belong to separate families. The family Vibrionaceae currently comprises eight validly published genera: Aliivibrio,^[2] Catenococcus, Enterovibrio, Grimontia, Listonella, Photobacterium, Salinivibrio, and Vibrio; although the status of Listonella has been questioned.

Members of this family also synthesize tetrodotoxin (TTX), an ancient marine alkaloid and powerful neurotoxin (Na+ pump inhibitor, 1 mg can kill an adult) that serves to protect members of an order of fishes, the Tetraodontiformes (tetras-four and odontos-tooth), which include the puffer fish (see fugu, raw puffer fish served in Japan). As mentioned above, Vibrionaceae bacteria are in symbiosis with many marine organisms.^[3] In the case of the puffer fish, and other marine organisms harboring TTX-producing Vibrionaceae, the symbiosis is an ancient and powerful one, providing protection against predation for the marine organisms that harbor these bacteria, while providing the bacteria a protected environment with plenty of nutrients for growth. TTX and saxitoxin provide good examples of convergent biochemical evolution: both toxins are extremely toxic at low levels, both are Na⁺ pump inhibitors and both have nearly identical binding constants on the Na⁺ pump in neurons.^[4]

A characteristic of the family is the broad host range susceptible to infection by vibrios. Pathogens of man, other than V. cholerae, include V. parahaemolyticus, a cause of gastroenteritis and V. vulnificus that can lead to acute and fatal septicaemia. Other species of Vibrionaceae are associated with disease in a wide variety of finfish, one of the most notable and commonly occurring pathogens being Vibrio anguillarum, the cause of septicaemia in farmed salmonids such as Atlantic salmon and rainbow trout.^[5] Species such as V. tubiashii cause disease in larval stages of Pacific oyster (Crassostrea gigas) while V. harveyi causes luminous vibriosis in penaeid shrimps (prawns). The extent of the host range is seen with species such as V. mediterranei and V. coralliilyticus, which can infect zooxanthellae, the plant symbionts of coral. These species of Vibrio are thought to be a cause of coral bleaching.^[6][7]