Trioxane
Trioxane refers to any of three isomeric organic compounds composed of a six-membered ring with three carbon atoms and three oxygen atoms, having the molecular formula C3H6O3.
Isomers
[edit]The three isomers are:
- 1,2,3-trioxane, a hypothetical compound that is the parent structure of the molozonides[1]
- 1,2,4-trioxane, a hypothetical compound whose skeleton occurs as a structural component of some antimalarial agents (artemisinin and similar drugs)[2]
- 1,3,5-trioxane, a trimer of formaldehyde used as fuel and in plastics manufacturing, and also as a solid fuel tablet when combined with hexamine
References
[edit]- ^ Lay, Tsan H.; Yamada, Takahiro; Tsai, Po-Lun; Bozzelli, Joseph W. (1997). "Thermodynamic Parameters and Group Additivity Ring Corrections for Three- to Six-Membered Oxygen Heterocyclic Hydrocarbons". Journal of Physical Chemistry A. 101 (13): 2471–2477. Bibcode:1997JPCA..101.2471L. doi:10.1021/jp9629497.
- ^ Gary H. Posner, Mikhail Krasavin, Michael McCutchen, Poonsakdi Ploypradith, John P. Maxwell, Jeffrey S. Elias, Michael H. Parker (2001). "New antimalarial trioxanes and endoperoxides". Antimalarial Chemotherapy: 255–263.
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