From Wikipedia, the free encyclopedia
Chemical compound
Lenograstim is a recombinant granulocyte colony-stimulating factor which functions as an immunostimulator.[1][2] It is developed by Chugai Pharmaceuticals under the brand name Granocyte.
- ^ "USAN Council. List No. 340. New names. Lenograstim". Clin. Pharmacol. Ther. 52 (1): 112–113. July 1992. doi:10.1038/clpt.1992.117. PMID 1284891. S2CID 221603616.
- ^ Amadori S, Suciu S, Jehn U, Stasi R, Thomas X, Marie JP, Muus P, Lefrère F, Berneman Z, Fillet G, Denzlinger C, Willemze R, Leoni P, Leone G, Casini M, Ricciuti F, Vignetti M, Beeldens F, Mandelli F, De Witte T (July 2005). "Use of glycosylated recombinant human G-CSF (lenograstim) during and/or after induction chemotherapy in patients 61 years of age and older with acute myeloid leukemia: final results of AML-13, a randomized phase-3 study". Blood. 106 (1): 27–34. doi:10.1182/blood-2004-09-3728. PMC 1895135. PMID 15761020.
|
|---|
| Chemokine | |
|---|
| CSF | |
|---|
| Interferon | | IFNAR (α/β, I) |
- Agonists: Albinterferon
- Interferon alpha (interferon alfa, IFN-α)
- Interferon alfa (IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21)
- Interferon alfa 2a
- Interferon alfa 2b
- Interferon alfa n1
- Interferon alfacon-1
- Interferon alpha-n3
- Interferon beta (IFN-β) (IFNB1, IFNB3)
- Interferon beta 1a
- Interferon beta 1b
- Interferon kappa (IFN-ε/κ/τ/ζ, IFNK)
- Interferon omega (IFN-ω, IFNW1)
- Peginterferon alfa-2a
- Peginterferon alfa-2b
|
|---|
| IFNGR (γ, II) | |
|---|
| IFNLR (λ, III) |
- See IL-28R (IFNLR) here instead.
|
|---|
|
|---|
| Interleukin | |
|---|
| TGFβ | |
|---|
| TNF | |
|---|
| Others | |
|---|
|
|---|
| Angiopoietin | |
|---|
| CNTF | |
|---|
| EGF (ErbB) | |
|---|
| FGF | | FGFR1 | |
|---|
| FGFR2 |
- Agonists: Ersofermin
- FGF (1, 2 (bFGF), 3, 4, 5, 6, 7 (KGF), 8, 9, 10 (KGF2), 17, 18, 22)
- Palifermin
- Repifermin
- Selpercatinib
- Sprifermin
- Trafermin
|
|---|
| FGFR3 | |
|---|
| FGFR4 | |
|---|
| Unsorted | |
|---|
|
|---|
| HGF (c-Met) | |
|---|
| IGF | |
|---|
| LNGF (p75NTR) | |
|---|
| PDGF | |
|---|
| RET (GFL) | |
|---|
| SCF (c-Kit) | |
|---|
| TGFβ | |
|---|
| Trk | | TrkA |
- Negative allosteric modulators: VM-902A
|
|---|
| TrkB |
- Agonists: 3,7-DHF
- 3,7,8,2'-THF
- 4'-DMA-7,8-DHF
- 7,3'-DHF
- 7,8-DHF
- 7,8,2'-THF
- 7,8,3'-THF
- Amitriptyline
- BDNF
- BNN-20
- Deoxygedunin
- Deprenyl
- Diosmetin
- DMAQ-B1
- HIOC
- LM22A-4
- N-Acetylserotonin
- NT-3
- NT-4
- Norwogonin (5,7,8-THF)
- R7
- R13
- TDP6
|
|---|
| TrkC | |
|---|
|
|---|
| VEGF | |
|---|
| Others |
- Additional growth factors: Adrenomedullin
- Colony-stimulating factors (see here instead)
- Connective tissue growth factor (CTGF)
- Ephrins (A1, A2, A3, A4, A5, B1, B2, B3)
- Erythropoietin (see here instead)
- Glucose-6-phosphate isomerase (GPI; PGI, PHI, AMF)
- Glia maturation factor (GMF)
- Hepatoma-derived growth factor (HDGF)
- Interleukins/T-cell growth factors (see here instead)
- Leukemia inhibitory factor (LIF)
- Macrophage-stimulating protein (MSP; HLP, HGFLP)
- Midkine (NEGF2)
- Migration-stimulating factor (MSF; PRG4)
- Oncomodulin
- Pituitary adenylate cyclase-activating peptide (PACAP)
- Pleiotrophin
- Renalase
- Thrombopoietin (see here instead)
- Wnt signaling proteins
- Additional growth factor receptor modulators: Cerebrolysin (neurotrophin mixture)
|
|---|
N
Y (what is this?) (verify)