Fluorexetamine

Fluorexetamine
Legal status
Legal status	CA: Schedule I; DE: NpSG (Industrial and scientific use only); UK: Class B; US: Unscheduled;
Identifiers
	IUPAC name 2-(ethylamino)-2-(3-fluorophenyl)cyclohexan-1-one;
PubChem CID	137332183;
UNII	AN89GB52AM;
CompTox Dashboard (EPA)	DTXSID701336920 ;
Chemical and physical data
Formula	C14H18FNO
Molar mass	235.302 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCNC1(CCCCC1=O)c1cccc(F)c1;
	InChI InChI=1S/C14H18FNO/c1-2-16-14(9-4-3-8-13(14)17)11-6-5-7-12(15)10-11/h5-7,10,16H,2-4,8-9H2,1H3; Key:FCETYWCLCUZFJI-UHFFFAOYSA-N;

Fluorexetamine (3'-Fluoro-2-oxo-PCE, 3-FXE) is a recreational designer drug from the arylcyclohexylamine family, with dissociative effects. It has reportedly been sold over the internet since around 2017, though has remained relatively uncommon.^[1]

In April 2023 it was revealed by DrugsData.org that all their previously analyzed samples of fluorexetamine actually contained 2'-Fluoro-2-oxo-PCE (2-FXE, also known as CanKet) rather than 3'-Fluoro-2-oxo PCE (3-FXE). This was confirmed by a newly available reference standard for 2-FXE.^[2] Similar misidentification may have occurred in other laboratories.

References

^ Wallach J, Brandt SD (2018). "1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances". Handbook of Experimental Pharmacology. 252: 305–352. doi:10.1007/164_2018_148. ISBN 978-3-030-10560-0. PMID 30196446.
^ Erowid, DrugsData org /. "DrugsData.org (was EcstasyData): Test Details : Result #15191 - White Crystals, 15191". www.drugsdata.org. Retrieved 2023-12-02.

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[pmid30196446-1] Wallach J, Brandt SD (2018). "1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances". Handbook of Experimental Pharmacology. 252: 305–352. doi:10.1007/164_2018_148. ISBN 978-3-030-10560-0. PMID 30196446.

[2] Erowid, DrugsData org /. "DrugsData.org (was EcstasyData): Test Details : Result #15191 - White Crystals, 15191". www.drugsdata.org. Retrieved 2023-12-02.

[1]

[2]

See also

References