TAF12

TAF12
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1H3O
Dynodwyr
Cyfenwau	TAF12, TAF2J, TAFII20, TATA-box binding protein associated factor 12
Dynodwyr allanol	OMIM: 600773 HomoloGene: 68477 GeneCards: TAF12
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001105 transcription coactivator activity • transcription factor binding • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • TBP-class protein binding • histone acetyltransferase activity Cydrannau o'r gell • transcription factor TFTC complex • transcription factor TFIID complex • nucleoplasm • cnewyllyn cell • SAGA complex • SLIK (SAGA-like) complex Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • positive regulation of DNA-binding transcription factor activity • transcription by RNA polymerase II • transcription, DNA-templated • DNA-templated transcription, initiation • transcription initiation from RNA polymerase II promoter • regulation of signal transduction by p53 class mediator • RNA polymerase II preinitiation complex assembly • histone H3 acetylation • positive regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6883	n/a
Ensembl	ENSG00000120656	n/a
UniProt	Q16514	n/a
RefSeq (mRNA)	NM_001135218 NM_005644	n/a
RefSeq (protein)	NP_001128690 NP_005635	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TAF12 yw TAF12 a elwir hefyd yn TATA-box binding protein associated factor 12 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p35.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TAF12.

• TAF2J
• TAFII20

• "Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease. ". J Bone Miner Res. 2013. PMID 23426901.
• "TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes. ". J Biol Chem. 2009. PMID 19635797.
• "Isolation and characterization of a cDNA encoding a novel human transcription factor TFIID subunit containing similarities with histones H2B and H3. ". Gene. 1996. PMID 8647459.
• "The involvement of the histone fold motifs in the mutual interaction between human TAF(II)80 and TAF(II)22. ". J Biochem. 1997. PMID 9133630.
• "Crystal structure of a subcomplex of human transcription factor TFIID formed by TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20).". J Biol Chem. 2002. PMID 12237304.