IL1R1

IL1R1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1G0Y, 1IRA, 1ITB, 4DEP, 4GAF
Dynodwyr
Cyfenwau	IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80, Interleukin 1 receptor, type I, interleukin 1 receptor type 1
Dynodwyr allanol	OMIM: 147810 HomoloGene: 677 GeneCards: IL1R1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • interleukin-1, type I, activating receptor activity • signal transducer activity • platelet-derived growth factor receptor binding • protease binding • GO:0001948, GO:0016582 protein binding • transmembrane signaling receptor activity • interleukin-1 receptor activity • interleukin-1 binding Cydrannau o'r gell • integral component of membrane • bilen • Cellbilen • integral component of plasma membrane • extracellular region • cell surface • external side of plasma membrane Prosesau biolegol • cell surface receptor signaling pathway • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • regulation of inflammatory response • GO:0072468 signal transduction • positive regulation of interleukin-1-mediated signaling pathway • positive regulation of neutrophil extravasation • response to interleukin-1 • cytokine-mediated signaling pathway • interleukin-1-mediated signaling pathway • positive regulation of interferon-gamma production • positive regulation of T-helper 1 cell cytokine production • inflammatory response Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3554	n/a
Ensembl	ENSG00000115594	n/a
UniProt	P14778	n/a
RefSeq (mRNA)	NM_000877 NM_001288706 NM_001320978 NM_001320980 NM_001320981 NM_001320982 NM_001320983 NM_001320984 NM_001320985 NM_001320986	n/a
RefSeq (protein)	NP_000868 NP_001275635 NP_001307907 NP_001307909 NP_001307910 NP_001307911 NP_001307912 NP_001307913 NP_001307914 NP_001307915	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IL1R1 yw IL1R1 a elwir hefyd yn Interleukin 1 receptor type 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q11.2-q12.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IL1R1.

• "Testing for Soluble ST2 in Heart Failure Patients: Reliability of a Point of Care Method. ". Clin Lab. 2017. PMID 28164491.
• "Variations in IL-1R1 Gene Influence Risk for Hepatitis B Virus Infection of Children in a Han Chinese population. ". Int J Infect Dis. 2017. PMID 28027994.
• "[Association between IL1R1 gene polymorphisms and childhood asthma]. ". Zhongguo Dang Dai Er Ke Za Zhi. 2016. PMID 26975823.
• "Serum CD121a (Interleukin 1 Receptor, Type I): A Potential Novel Inflammatory Marker for Coronary Heart Disease. ". PLoS One. 2015. PMID 26098632.
• "IL-1R1 is expressed on both Helios(+) and Helios(-) FoxP3(+) CD4(+) T cells in the rheumatic joint.". Clin Exp Immunol. 2015. PMID 26076982.