ICAM3

ICAM3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1T0P
Dynodwyr
Cyfenwau	ICAM3, CD50, CDW50, ICAM-R, intercellular adhesion molecule 3
Dynodwyr allanol	OMIM: 146631 HomoloGene: 88479 GeneCards: ICAM3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • integrin binding • signaling receptor binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • integral component of membrane • Cellbilen • integral component of plasma membrane • extracellular exosome • bilen Prosesau biolegol • cell adhesion • extracellular matrix organization • stimulatory C-type lectin receptor signaling pathway • regulation of immune response • ffagocytosis • cell-cell adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3385	n/a
Ensembl	ENSG00000076662	n/a
UniProt	P32942	n/a
RefSeq (mRNA)	NM_002162 NM_001320605 NM_001320606 NM_001320608 NM_001395374 NM_001395375 NM_001395376	n/a
RefSeq (protein)	NP_001307534 NP_001307535 NP_001307537 NP_002153	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ICAM3 yw ICAM3 a elwir hefyd yn Intercellular adhesion molecule 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ICAM3.

• CD50
• CDW50
• ICAM-R

• "ICAM-3 endows anticancer drug resistance against microtubule-damaging agents via activation of the ICAM-3-AKT/ERK-CREB-2 pathway and blockage of apoptosis. ". Biochem Biophys Res Commun. 2013. PMID 24177012.
• "Novel role of ICAM3 and LFA-1 in the clearance of apoptotic neutrophils by human macrophages. ". Apoptosis. 2013. PMID 23775590.
• "Characterization of a distinct population of circulating human non-adherent endothelial forming cells and their recruitment via intercellular adhesion molecule-3. ". PLoS One. 2012. PMID 23144795.
• "Functional role of ICAM-3 polymorphism in genetic susceptibility to SARS infection. ". Hong Kong Med J. 2009. PMID 19801714.
• "Intercellular adhesion molecule-3 binding of integrin alphaL beta2 requires both extension and opening of the integrin headpiece.". J Immunol. 2008. PMID 18354203.