ADH7

ADH7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1AGN, 1D1S, 1D1T
Dynodwyr
Cyfenwau	ADH7, ADH4, alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Dynodwyr allanol	OMIM: 600086 HomoloGene: 37333 GeneCards: ADH7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0050250, GO:0102797, GO:0102798 aldehyde oxidase activity • zinc ion binding • metal ion binding • NAD-retinol dehydrogenase activity • ethanol binding • retinol binding • oxidoreductase activity • receptor antagonist activity • alcohol dehydrogenase (NAD+) activity • alcohol dehydrogenase activity, zinc-dependent Cydrannau o'r gell • cytoplasm • intracellular anatomical structure • extracellular region • cytosol • Cellbilen Prosesau biolegol • ethanol catabolic process • response to bacterium • retinol metabolic process • retinoic acid metabolic process • fatty acid omega-oxidation • retinoid metabolic process • response to ethanol • ethanol oxidation • extracellular negative regulation of signal transduction • negative regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	131	n/a
Ensembl	ENSG00000196344	n/a
UniProt	P40394	n/a
RefSeq (mRNA)	NM_001166504 NM_000673	n/a
RefSeq (protein)	NP_000664 NP_001159976	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ADH7 yw ADH7 a elwir hefyd yn Alcohol dehydrogenase class 4 mu/sigma chain ac Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q23.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ADH7.

• ADH4

• "Protective variant associated with alcohol dependence in a Mexican American cohort. ". BMC Med Genet. 2014. PMID 25527893.
• "Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) activity in the sera of patients with gastric cancer. ". Dig Dis Sci. 2008. PMID 18231859.
• "Association of the gastric alcohol dehydrogenase gene ADH7 with variation in alcohol metabolism. ". Hum Mol Genet. 2008. PMID 17921519.
• "ADH7 variation modulates extraversion and conscientiousness in substance-dependent subjects. ". Am J Med Genet B Neuropsychiatr Genet. 2008. PMID 17918242.
• "Identification of new single nucleotid polymorphisms (SNP) in alcohol dehydrogenase class IV ADH7 gene within a French population.". Arch Toxicol. 2006. PMID 16180008.