F11R

F11R
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1NBQ, 3EOY, 3TSZ, 4ODB
Dynodwyr
Cyfenwau	F11R, F11r, 9130004G24, AA638916, ESTM33, JAM, JAM-1, JAM-A, Jcam, Jcam1, Ly106, CD321, JAM1, JAMA, KAT, PAM-1, F11 receptor
Dynodwyr allanol	OMIM: 605721 HomoloGene: 14255 GeneCards: F11R
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • PDZ domain binding • virus receptor activity • GO:0001948, GO:0016582 protein binding • cadherin binding Cydrannau o'r gell • integral component of membrane • bilen • cell-cell junction • bicellular tight junction • Cellbilen • slit diaphragm • extracellular exosome • GO:0016023 cytoplasmic vesicle • cell junction Prosesau biolegol • regulation of actin cytoskeleton reorganization • cell differentiation • establishment of endothelial intestinal barrier • epithelial cell differentiation • actomyosin structure organization • extracellular matrix organization • regulation of membrane permeability • GO:0032657 regulation of cytokine production • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • positive regulation of blood pressure • cell adhesion • GO:0034259 negative regulation of GTPase activity • bicellular tight junction assembly • viral entry into host cell • intestinal absorption • response to radiation • inflammatory response • GO:0022415 viral process • transforming growth factor beta receptor signaling pathway • leukocyte migration • protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	50848	n/a
Ensembl	ENSG00000158769	n/a
UniProt	Q9Y624	n/a
RefSeq (mRNA)	NM_016946 NM_144501 NM_144502 NM_144503 NM_144504 NM_001348091 NM_001382727 NM_001382730 NM_001382733 NM_001382734	n/a
RefSeq (protein)	NP_058642 NP_001335020 NP_001369656 NP_001369659 NP_001369662 NP_001369663	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn F11R yw F11R a elwir hefyd yn F11 receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q23.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn F11R.

• "Junctional Adhesion Molecule-A in Head and Neck Squamous Cell Carcinoma. ". Adv Otorhinolaryngol. 2016. PMID 27115511.
• "Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF. ". Mol Biol Cell. 2016. PMID 26985018.
• "A novel immunotoxin reveals a new role for CD321 in endothelial cells. ". PLoS One. 2017. PMID 29028806.
• "Elevated expression of JAM-A promotes neoplastic properties of lung adenocarcinoma. ". Cancer Sci. 2017. PMID 28837251.
• "Identification of Human Junctional Adhesion Molecule 1 as a Functional Receptor for the Hom-1 Calicivirus on Human Cells.". MBio. 2017. PMID 28196955.