File:Finasteride Mechanism.png

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English: This is the mechanism of inhibition for Finasteride on 5α-Reductase. Finasteride works to inhibit 5α-Reductase through competitive inhibition, which is why the mechanism shows the NADP+ getting attacked by the enolate formed rather than instant tautamerization occurring like in the case of 5α-Reductase's work on testosterone. Finasteride does eventually get released from 5α-Reductase enzyme-substrate complex which is why it is not considered a suicide inhibitor as the product eventually formed is dihydrofinasteride.
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Author SJKH183

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Date/TimeThumbnailDimensionsUserComment
current07:40, 7 March 2021Thumbnail for version as of 07:40, 7 March 20211,700 × 1,100 (186 KB)SJKH183 (talk | contribs)Uploaded own work with UploadWizard

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