VTA1

VTA1
Dostupne strukture
PDB	Pretraga ortologa: PDBe RCSB
Spisak PDB ID kodova
	2LXL, 2LXM, 4TXP, 4TXQ, 4TXR, 4U7E
Identifikatori
Aliasi	VTA1
Vanjski ID-jevi	OMIM: 610902 MGI: 1913451 HomoloGene: 6473 GeneCards: VTA1
Lokacija gena (čovjek)
Hrom.	Hromosom 6 (čovjek)
Kraj	142,224,685 bp
Lokacija gena (miš)
Hrom.	Hromosom 10 (miš)
Kraj	14,581,304 bp
Ontologija gena
Molekularna funkcija	• protein C-terminus binding; • GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• citoplazma; • citosol; • endozom; • endosome membrane; • Egzosom; • membrana; • nukleoplazma; • intracellular membrane-bounded organelle;
Biološki proces	• protein transport; • endosomal transport; • multivesicular body assembly; • GO:0019067 viral life cycle; • multivesicular body sorting pathway; • ESCRT III complex disassembly; • macroautophagy; • GO:0015915 transport;
	Izvori:Amigo / QuickGO
Ortolozi
	51534
	66201
	ENSG00000009844
	ENSMUSG00000019868
	Q9NP79
	Q9CR26
	NM_016485; NM_001286371; NM_001286372
	NM_025418
	NP_001273300; NP_001273301; NP_057569
	NP_079694
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Sortiranjem pridruženi VTA1 homolog vakuolskog proteina jest protein koji je kod ljudi kodiran genom VTA1.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 307 aminokiselina, а molekulska težina 33.879 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MAALAPLPPL	PAQFKSIQHH	LRTAQEHDKR	DPVVAYYCRL	YAMQTGMKID
SKTPECRKFL	SKLMDQLEAL	KKQLGDNEAI	TQEIVGCAHL	ENYALKMFLY
ADNEDRAGRF	HKNMIKSFYT	ASLLIDVITV	FGELTDENVK	HRKYARWKAT
YIHNCLKNGE	TPQAGPVGIE	EDNDIEENED	AGAASLPTQP	TQPSSSSTYD
PSNMPSGNYT	GIQIPPGAHA	PANTPAEVPH	STGVASNTIQ	PTPQTIPAID
PALFNTISQG	DVRLTPEDFA	RAQKYCKYAG	SALQYEDVST	AVQNLQKALK
LLTTGRE

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000009844 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000019868 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Shi J, Cai W, Chen X, Ying K, Zhang K, Xie Y (Aug 2001). "Identification of dopamine responsive mRNAs in glial cells by suppression subtractive hybridization". Brain Res. 910 (1–2): 29–37. doi:10.1016/S0006-8993(01)02393-9. PMID 11489251. S2CID 43814085.
^ "Entrez Gene: C6orf55 chromosome 6 open reading frame 55".
^ "UniProt, Q9NP79" (jezik: engleski). Pristupljeno 9. 10. 2021.

Dopunska literatura

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Tchernev VT, Mansfield TA, Giot L, et al. (2002). "The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins". Mol. Med. 8 (1): 56–64. doi:10.1007/bf03402003. PMC 2039936. PMID 11984006.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Fujita H, Umezuki Y, Imamura K, et al. (2005). "Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B". J. Cell Sci. 117 (Pt 14): 2997–3009. doi:10.1242/jcs.01170. PMID 15173323.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000009844 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000019868 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11489251-5] Shi J, Cai W, Chen X, Ying K, Zhang K, Xie Y (Aug 2001). "Identification of dopamine responsive mRNAs in glial cells by suppression subtractive hybridization". Brain Res. 910 (1–2): 29–37. doi:10.1016/S0006-8993(01)02393-9. PMID 11489251. S2CID 43814085.

[entrez-6] "Entrez Gene: C6orf55 chromosome 6 open reading frame 55".

[UniProt-7] "UniProt, Q9NP79" (jezik: engleski). Pristupljeno 9. 10. 2021.

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