S Wikipedije, slobodne enciklopedije
Proteinoliki proteina 1 nukleosomskog sklopa je protein koji je kod ljudi kodiran genom NAP1L1 .[ 4] [ 5]
Ovaj gen kodira člana porodice proteina nukleosomkog sklopa (NAP). Ovaj protein sudjeluje u replikaciji DNK i može imati ulogu u moduliranju stvaranja hromatina i pridonijeti regulaciji ćelijske proliferacije . Alternativna prerada RNK ovog gena dovodi do nekoliko varijanti transkripta; međutim, nisu sve u potpunosti opisane.[ 5]
Dužina polipeptidnog lanca je 391 aminokiselina , a molekulska težina 45.374 Da .[ 6] .
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MADIDNKEQS ELDQDLDDVE EVEEEETGEE TKLKARQLTV QMMQNPQILA
ALQERLDGLV ETPTGYIESL PRVVKRRVNA LKNLQVKCAQ IEAKFYEEVH
DLERKYAVLY QPLFDKRFEI INAIYEPTEE ECEWKPDEED EISEELKEKA
KIEDEKKDEE KEDPKGIPEF WLTVFKNVDL LSDMVQEHDE PILKHLKDIK
VKFSDAGQPM SFVLEFHFEP NEYFTNEVLT KTYRMRSEPD DSDPFSFDGP
EIMGCTGCQI DWKKGKNVTL KTIKKKQKHK GRGTVRTVTK TVSNDSFFNF
FAPPEVPESG DLDDDAEAIL AADFEIGHFL RERIIPRSVL YFTGEAIEDD
DDDYDEEGEE ADEEGEEEGD EENDPDYDPK KDQNPAECKQ Q
Simboli
^ a b c GRCh38: Ensembl release 89: ENSG00000187109 - Ensembl , maj 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Simon HU, Mills GB, Kozlowski M, Hogg D, Branch D, Ishimi Y, Siminovitch KA (Mar 1994). "Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation" . Biochem J . 297 (2): 389–97. doi :10.1042/bj2970389 . PMC 1137842 . PMID 8297347 .
^ a b "Entrez Gene: NAP1L1 nucleosome assembly protein 1-like 1" .
^ "UniProt, P55209" . Pristupljeno 12. 8. 2021 .
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