Quercetin Enhances the Anti-Tumor Effects of BET Inhibitors by Suppressing hnRNPA1 (Q93081341)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31480735%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

title

Quercetin Enhances the Anti-Tumor Effects of BET Inhibitors by Suppressing hnRNPA1 (English)

1 reference

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3 May 2020

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3 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31480735%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Sophie Stempel

1 reference

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3 May 2020

Mario A Shields

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3 May 2020

Christina Spaulding

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3 May 2020

David J Bentrem

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3 May 2020

Maria Matsangou

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3 May 2020

Hidayatullah G Munshi

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3 May 2020

Thao N. D. Pham

0 references

Mario A. Shields

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Krishan Kumar

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David J. Bentrem

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Hidayatullah G. Munshi

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language of work or name

English

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publication date

2 September 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31480735%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

3 May 2020

January 2019

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https://www.mdpi.com/1422-0067/20/17/4293

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published in

International Journal of Molecular Sciences

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3 May 2020

volume

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3 May 2020

issue

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Creative Commons Attribution 4.0 International

3 May 2020

page(s)

4293

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start time

2 September 2019

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April 2022 Public Data File from Crossref

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6747365/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Induction of MNK Kinase-dependent eIF4E Phosphorylation by Inhibitors Targeting BET Proteins Limits Efficacy of BET Inhibitors

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11 February 2021

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Emerging roles of hnRNPA1 in modulating malignant transformation

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Quercetin Targets hnRNPA1 to Overcome Enzalutamide Resistance in Prostate Cancer Cells

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Synergistic inhibition of migration and invasion of breast cancer cells by dual docetaxel/quercetin-loaded nanoparticles via Akt/MMP-9 pathway

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Quercetin induces apoptosis and cell cycle arrest in triple-negative breast cancer cells through modulation of Foxo3a activity

11 February 2021

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BET inhibitors block pancreatic stellate cell collagen I production and attenuate fibrosis in vivo

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Hyaluronic Acid Nanohydrogel Loaded With Quercetin Alone or in Combination to a Macrolide Derivative of Rapamycin RAD001 (Everolimus) as a New Treatment for Hormone-Responsive Human Breast Cancer.

11 February 2021

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Up-regulation of microRNA let-7c by quercetin inhibits pancreatic cancer progression by activation of Numbl

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11 February 2021

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Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells

11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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Quercetin Enhances Cisplatin Sensitivity of Human Osteosarcoma Cells by Modulating microRNA-217-KRAS Axis

11 February 2021

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GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1.

11 February 2021

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MicroRNA regulation and therapeutic targeting of survivin in cancer

11 February 2021

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11 February 2021

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hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.

11 February 2021

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BET bromodomain inhibitors block growth of pancreatic cancer cells in three-dimensional collagen

11 February 2021

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hnRNP A1: the Swiss army knife of gene expression

11 February 2021

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Quercetin increases the efficacy of glioblastoma treatment compared to standard chemoradiotherapy by the suppression of PI-3-kinase-Akt pathway

11 February 2021

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Snail cooperates with KrasG12D to promote pancreatic fibrosis

11 February 2021

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Quercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xl

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

Quercetin-induced apoptosis of HL-60 cells by reducing PI3K/Akt

11 February 2021

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Quercetin inhibits human breast cancer cell proliferation and induces apoptosis via Bcl-2 and Bax regulation

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

11 February 2021

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Pancreatic Cancer Cells Respond to Type I Collagen by Inducing Snail Expression to Promote Membrane Type 1 Matrix Metalloproteinase-dependent Collagen Invasion

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of Bax.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

Quercetin modulates NF-kappa B and AP-1/JNK pathways to induce cell death in human hepatoma cells.

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

Role of Bax in quercetin-induced apoptosis in human prostate cancer cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

Subcellular relocalization of a trans-acting factor regulates XIAP IRES-dependent translation.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

Quercetin induces p53-independent apoptosis in human prostate cancer cells by modulating Bcl-2-related proteins: a possible mediation by IGFBP-3.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

Small interfering RNA-mediated reduction in heterogeneous nuclear ribonucleoparticule A1/A2 proteins induces apoptosis in human cancer cells but not in normal mortal cell lines.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6747365

11 February 2021

Identifiers

DOI

10.3390/IJMS20174293

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31480735%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31480735%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

PubMed publication ID

31480735

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31480735%20AND%20SRC:MED&resulttype=core&format=json