GLIPR1 expression is reduced in multiple myeloma but is not a tumour suppressor in mice (Q93032105)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

title

GLIPR1 expression is reduced in multiple myeloma but is not a tumour suppressor in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Jacqueline E Noll

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Khatora S Opperman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Krzysztof M Mrozik

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Duncan R Hewett

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

Andrew C W Zannettino

1 reference

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3 May 2020

publication date

29 January 2020

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3 May 2020

1 reference

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3 May 2020

volume

1 reference

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3 May 2020

issue

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3 May 2020

page(s)

e0228408

1 reference

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Creative Commons Attribution 4.0 International

3 May 2020

start time

29 January 2020

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6988976/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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PD-L1, LAG3, and HLA-DR are increasingly expressed during smoldering myeloma progression

11 February 2021

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11 February 2021

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11 February 2021

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Genomic patterns of progression in smoldering multiple myeloma

11 February 2021

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Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability

11 February 2021

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11 February 2021

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Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.

11 February 2021

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11 February 2021

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TPX2-p53-GLIPR1 regulatory circuitry in cell proliferation, invasion and tumor growth of bladder cancer.

11 February 2021

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Bortezomib with lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone in patients with newly diagnosed myeloma without intent for immediate autologous stem-cell transplant (SWOG S0777): a randomised, open-label, phase 3 trial

11 February 2021

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11 February 2021

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Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma.

11 February 2021

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GLIPR1 inhibits the proliferation and induces the differentiation of cancer-initiating cells by regulating miR-16 in osteosarcoma

11 February 2021

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Phenotypic, transcriptomic, and genomic features of clonal plasma cells in light-chain amyloidosis

11 February 2021

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GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer

11 February 2021

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11 February 2021

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Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.

11 February 2021

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Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.

11 February 2021

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International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma

11 February 2021

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SAMSN1 is a tumor suppressor gene in multiple myeloma

11 February 2021

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Outcome prediction in plasmacytoma of bone: a risk model utilizing bone marrow flow cytometry and light-chain analysis.

11 February 2021

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Multiparameter flow cytometry for staging of solitary bone plasmacytoma: new criteria for risk of progression to myeloma

11 February 2021

1 reference

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Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients

11 February 2021

1 reference

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Promiscuous MYC locus rearrangements hijack enhancers but mostly super-enhancers to dysregulate MYC expression in multiple myeloma.

11 February 2021

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Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma

11 February 2021

1 reference

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Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy

11 February 2021

1 reference

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Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

11 February 2021

1 reference

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Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells.

11 February 2021

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Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

11 February 2021

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Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.

11 February 2021

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Genetic background and tumour susceptibility in mouse models

11 February 2021

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Myeloma is characterized by stage-specific alterations in DNA methylation that occur early during myelomagenesis

11 February 2021

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Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2.

11 February 2021

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Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma.

11 February 2021

1 reference

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SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status

11 February 2021

1 reference

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Clonal competition with alternating dominance in multiple myeloma.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

The genetic architecture of multiple myeloma.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Bone marrow angiogenesis and progression in multiple myeloma

11 February 2021

1 reference

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Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with Total Therapy 3

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Initial genome sequencing and analysis of multiple myeloma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Examining Hedgehog pathway genes GLI3, SHH, and PTCH1 and the p53 target GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster using fluorescence in situ hybridization uncovers GLIPR1/GLIPR1L1/GLIPR1L2 deletion in 9% of patients with multiple myeloma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Targeted disruption of the CXCL12/CXCR4 axis inhibits osteolysis in a murine model of myeloma-associated bone loss

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

A monoclonal gammopathy precedes multiple myeloma in most patients

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

The CAP superfamily: cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins--roles in reproduction, cancer, and immune defense

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Glioma pathogenesis-related protein 1 exerts tumor suppressor activities through proapoptotic reactive oxygen species-c-Jun-NH2 kinase signaling.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Molecular Dissection of Hyperdiploid Multiple Myeloma by Gene Expression Profiling

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

The molecular classification of multiple myeloma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene cluster

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Adenoviral vector-mediated mRTVP-1 gene therapy for prostate cancer

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

mRTVP-1, a novel p53 target gene with proapoptotic activities

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

RAG-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

A long-term study of prognosis in monoclonal gammopathy of undetermined significance.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Ibandronate reduces osteolytic lesions but not tumor burden in a murine model of myeloma bone disease

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Targeted expression of MYCN causes neuroblastoma in transgenic mice

11 February 2021

1 reference

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A murine model of human myeloma bone disease

11 February 2021

1 reference

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Effects of genetic background on tumorigenesis in p53-deficient mice

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Influence of treatment with APD-bisphosphonate on the bone lesions in the mouse 5T2 multiple myeloma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

The 5T2 mouse multiple myeloma model: characterization of 5T2 cells within the bone marrow

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Animal model of human disease. Multiple myeloma.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Idiopathic paraproteinemia. II. Transplantation of the paraprotein-producing clone from old to young C57BL/KaLwRij mice

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

Idiopathic paraproteinaemia. I. Studies in an animal model--the ageing C57BL/KaLwRij mouse

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6988976

10.1371/JOURNAL.PONE.0228408

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

PubMed publication ID

31995627

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31995627%20AND%20SRC:MED&resulttype=core&format=json