Innate immunity to intracellular LPS (Q92955579)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30962589%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

title

Innate immunity to intracellular LPS (English)

1 reference

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2 May 2020

1 reference

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2 May 2020

Vijay A K Rathinam

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30962589%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Yue Zhao

series ordinal

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2 May 2020

publication date

8 April 2019

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2 May 2020

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2 May 2020

volume

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2 May 2020

issue

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2 May 2020

page(s)

527-533

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Pattern recognition receptors and inflammation

2 May 2020

cites work

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Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.

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7 January 2021

Shigella flexneri induces apoptosis in infected macrophages

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7 January 2021

Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

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7 January 2021

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

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7 January 2021

Diverse mechanisms for inflammasome sensing of cytosolic bacteria and bacterial virulence

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7 January 2021

Inflammasomes: mechanism of assembly, regulation and signalling

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7 January 2021

Lipopolysaccharide endotoxins

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7 January 2021

The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

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7 January 2021

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

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7 January 2021

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

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7 January 2021

Non-canonical inflammasome activation targets caspase-11

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7 January 2021

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

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7 January 2021

Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock

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7 January 2021

Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

1 reference

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7 January 2021

The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

1 reference

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7 January 2021

Inflammatory caspases are innate immune receptors for intracellular LPS.

1 reference

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7 January 2021

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

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7 January 2021

Complement pathway amplifies caspase-11-dependent cell death and endotoxin-induced sepsis severity.

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7 January 2021

Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization

1 reference

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7 January 2021

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

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7 January 2021

Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Caspase-11 protects against bacteria that escape the vacuole

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Pore-forming activity and structural autoinhibition of the gasdermin family

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

1 reference

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7 January 2021

Cryo-EM structure of the gasdermin A3 membrane pore.

1 reference

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7 January 2021

Mechanism of membrane pore formation by human gasdermin-D

1 reference

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7 January 2021

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

1 reference

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7 January 2021

The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.

1 reference

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7 January 2021

The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice

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7 January 2021

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

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7 January 2021

Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice

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7 January 2021

Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens

1 reference

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7 January 2021

Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells

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7 January 2021

Caspase-11-dependent pyroptosis of lung epithelial cells protects from melioidosis while caspase-1 mediates macrophage pyroptosis and production of IL-18.

1 reference

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7 January 2021

Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux

1 reference

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7 January 2021

Emerging Insights into Noncanonical Inflammasome Recognition of Microbes

1 reference

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7 January 2021

Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium

1 reference

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7 January 2021

Caspase-11 deficiency impairs neutrophil recruitment and bacterial clearance in the early stage of pulmonary Klebsiella pneumoniae infection

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Biological functions and biogenesis of secreted bacterial outer membrane vesicles

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Immune modulation by bacterial outer membrane vesicles.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Dysregulated hemolysin liberates bacterial outer membrane vesicles for cytosolic lipopolysaccharide sensing

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

High-affinity caspase-4 binding to LPS presented as high molecular mass aggregates or in outer membrane vesicles

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Membrane vesicles from Pseudomonas aeruginosa activate the noncanonical inflammasome through caspase-5 in human monocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Toll Like Receptor 4 Signaling Licenses the Cytosolic Transport of Lipopolysaccharide from Bacterial Outer Membrane Vesicles.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Interferon-induced guanylate-binding proteins in inflammasome activation and host defense

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

GBPs Inhibit Motility of Shigella flexneri but Are Targeted for Degradation by the Bacterial Ubiquitin Ligase IpaH9.8.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Lipid Peroxidation Adds Fuel to Pyr(optosis)

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Stearoyl Lysophosphatidylcholine Inhibits Endotoxin-Induced Caspase-11 Activation

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021

Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose

1 reference

https://api.crossref.org/works/10.1038%2FS41590-019-0368-3

7 January 2021