Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast Cancer (Q92667609)

PubMed publication ID

31420371

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31420371%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

title

Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast Cancer (English)

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12 May 2020

author

Vidyalakshmi Sethunath

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12 May 2020

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12 May 2020

1 reference

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12 May 2020

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12 May 2020

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12 May 2020

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12 May 2020

Rachel Schiff

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12 May 2020

Joe W Gray

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12 May 2020

Britta Weigelt

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12 May 2020

Huizhong Hu

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12 May 2020

Jamunarani Veeraraghavan

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12 May 2020

Lanfang Qin

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12 May 2020

Nicholas Wang

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12 May 2020

Lukas M Simon

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12 May 2020

Xiaoyong Fu

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12 May 2020

Agostina Nardone

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12 May 2020

Resel Pereira

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12 May 2020

Sarmistha Nanda

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12 May 2020

Anna Tsimelzon

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12 May 2020

Chad Shaw

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12 May 2020

Gary C Chamness

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12 May 2020

Jorge S Reis-Filho

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12 May 2020

Shixia Huang

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12 May 2020

Mothaffar F Rimawi

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12 May 2020

C Kent Osborne

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12 May 2020

publication date

16 August 2019

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PubMed publication ID

31420371

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31420371%20AND%20SRC:MED&resulttype=core&format=json

Molecular Cancer Research

1 May 2020

published in

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12 May 2020

volume

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12 May 2020

issue

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12 May 2020

page(s)

2318-2330

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Lipophilic statins antagonistically alter the major epithelial-to-mesenchymal transition signaling pathways in breast cancer stem-like cells via inhibition of the mevalonate pathway

12 May 2020

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The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells.

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11 February 2021

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Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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TEAD mediates YAP-dependent gene induction and growth control

11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and squalene synthase

11 February 2021

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11 February 2021

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10.1158/1541-7786.MCR-19-0756

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6825570&resulttype=core&format=json

12 May 2020

1 reference

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12 May 2020

PubMed publication ID

31420371

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6825570&resulttype=core&format=json