The evolving role of T-bet in resistance to infection (Q92209373)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30846856%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

title

The evolving role of T-bet in resistance to infection (English)

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27 April 2020

author

Gretchen Harms Pritchard

series ordinal

object named as

Gretchen Harms Pritchard

1 reference

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27 April 2020

Ross M Kedl

1 reference

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27 April 2020

Christopher A Hunter

series ordinal

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27 April 2020

publication date

1 June 2019

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Nature Reviews Immunology

27 April 2020

published in

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27 April 2020

volume

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27 April 2020

issue

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27 April 2020

page(s)

398-410

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The Thymus and the Precursors of Antigen Reactive Cells

27 April 2020

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T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.

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7 January 2021

T-Bet expression and failure of GATA-3 cross-regulation lead to default production of IFN-gamma by gammadelta T cells

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7 January 2021

T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells

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7 January 2021

The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells

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7 January 2021

Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages

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7 January 2021

T-bet-dependent NKp46+ innate lymphoid cells regulate the onset of TH17-induced neuroinflammation.

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7 January 2021

The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.

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7 January 2021

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

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7 January 2021

IL-21 promotes CD8+ CTL activity via the transcription factor T-bet

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7 January 2021

Type-I IFN drives the differentiation of short-lived effector CD8+ T cells in vivo.

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7 January 2021

mTORC1 Promotes T-bet Phosphorylation To Regulate Th1 Differentiation

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7 January 2021

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7 January 2021

Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division

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The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

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The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection.

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Diverse roles for T-bet in the effector responses required for resistance to infection.

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Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

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Expression of chemokine receptor CXCR3 on T cells affects the balance between effector and memory CD8 T-cell generation

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T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.

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P-selectin glycoprotein ligand-1 (PSGL-1) on T helper 1 but not on T helper 2 cells binds to P-selectin and supports migration into inflamed skin

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Lack of functional P-selectin ligand exacerbates Salmonella serovar typhimurium infection.

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7 January 2021

IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection

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7 January 2021

An extrafollicular pathway for the generation of effector CD8(+) T cells driven by the proinflammatory cytokine, IL-12.

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7 January 2021

Ly6C induces clustering of LFA-1 (CD11a/CD18) and is involved in subtype-specific adhesion of CD8 T cells

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7 January 2021

Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration

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7 January 2021

Ly-6C regulates endothelial adhesion and homing of CD8(+) T cells by activating integrin-dependent adhesion pathways

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7 January 2021

The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology

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7 January 2021

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7 January 2021

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7 January 2021

Distinct requirements for T-bet in gut innate lymphoid cells

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7 January 2021

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells

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7 January 2021

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

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7 January 2021

The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation

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7 January 2021

T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow

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7 January 2021

Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking

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Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response.

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7 January 2021

Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens

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7 January 2021

Murine cutaneous leishmaniasis: susceptibility correlates with differential expansion of helper T-cell subsets

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7 January 2021

Disseminated tuberculosis in interferon gamma gene-disrupted mice

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Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production

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7 January 2021

Expression of T-bet by CD4 T cells is essential for resistance to Salmonella infection.

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7 January 2021

Cutting edge: immunity and IFN-gamma production during Listeria monocytogenes infection in the absence of T-bet.

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7 January 2021

Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells

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7 January 2021

Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.

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7 January 2021

IRF4 Regulates the Ratio of T-Bet to Eomesodermin in CD8+ T Cells Responding to Persistent LCMV Infection

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7 January 2021

The role of the integrin LFA-1 in T-lymphocyte migration

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7 January 2021

Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells

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7 January 2021

The transcription factor T-bet regulates parasitemia and promotes pathogenesis during Plasmodium berghei ANKA murine malaria

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7 January 2021

T-bet inhibits the in vivo differentiation of parasite-specific CD4+ Th17 cells in a T cell-intrinsic manner

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https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

T-bet-dependent regulation of CD8+ T-cell expansion during experimental Trypanosoma cruzi infection

1 reference

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7 January 2021

IL-17 is necessary for host protection against acute-phase Trypanosoma cruzi infection

1 reference

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7 January 2021

Interleukin-17 protects against the Francisella tularensis live vaccine strain but not against a virulent F. tularensis type A strain

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

T-bet regulates immunity to Francisella tularensis live vaccine strain infection, particularly in lungs

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Th1 Differentiation Drives the Accumulation of Intravascular, Non-protective CD4 T Cells during Tuberculosis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

STAT4 and T-bet control follicular helper T cell development in viral infections.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Transient T-bet expression functionally specifies a distinct T follicular helper subset

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

T-bet regulates IgG class switching and pathogenic autoantibody production

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

T-bet regulates T-independent IgG2a class switching

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Stat1-dependent synergistic activation of T-bet for IgG2a production during early stage of B cell activation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Age-Associated B Cells: A T-bet-Dependent Effector with Roles in Protective and Pathogenic Immunity

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7 January 2021

Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells.

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7 January 2021

Divergent transcriptional programming of class-specific B cell memory by T-bet and RORα

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https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

IFN-γ produced by CD8 T cells induces T-bet–dependent and –independent class switching in B cells in responses to alum-precipitated protein vaccine

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Role of CD11c(+) T-bet(+) B cells in human health and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Age-associated B cells: key mediators of both protective and autoreactive humoral responses

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Cutting Edge: B Cell-Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Hepatitis C viraemia reversibly maintains subset of antigen-specific T-bet+ tissue-like memory B cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Generation of CD8 T cell memory is regulated by IL-12.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Clonal expansion of vaccine-elicited T cells is independent of aerobic glycolysis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Diversity in T cell memory: an embarrassment of riches

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Effector-like CD8⁺ T cells in the memory population mediate potent protective immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Continuous Effector CD8(+) T Cell Production in a Controlled Persistent Infection Is Sustained by a Proliferative Intermediate Population

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Functional classification of memory CD8(+) T cells by CX3CR1 expression

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

T-bet, GATA-3, and Foxp3 expression and Th1/Th2 cytokine production in the clinical outcome of human infection with Leishmania (Viannia) species

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Increased T-bet is associated with senescence of influenza virus-specific CD8 T cells in aged humans

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Identification of a novel type 1 diabetes susceptibility gene, T-bet

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

A 3'-untranslated region polymorphism in the TBX21 gene encoding T-bet is a risk factor for genital herpes simplex virus type 2 infection in humans

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

Protective immunity to genital herpes simplex [correction of simpex] virus type 2 infection is mediated by T-bet

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0145-4

7 January 2021

10.1038/S41577-019-0145-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30846856%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30846856%20AND%20SRC:MED&resulttype=core&format=json