Multi-Target β-Protease Inhibitors from Andrographis paniculata: In Silico and In Vitro Studies (Q91994595)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31319560%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

title

Multi-Target β-Protease Inhibitors from Andrographis paniculata: In Silico and In Vitro Studies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31319560%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

main subject

Andrographis paniculata

object named as

Andrographis paniculata

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31319560%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

Archana N Panche

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31319560%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

Sheela Chandra

series ordinal

1 reference

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26 April 2020

publication date

17 July 2019

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26 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31319560%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

volume

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26 April 2020

issue

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Creative Commons Attribution 4.0 International

26 April 2020

start time

17 July 2019

1 reference

April 2022 Public Data File from Crossref

copyrighted

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Alzheimer's disease: genes, proteins, and therapy

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

The neuroprotective effects of phytoestrogens on amyloid beta protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Acetylthiocholine binds to asp74 at the peripheral site of human acetylcholinesterase as the first step in the catalytic pathway

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Purification and cloning of amyloid precursor protein beta-secretase from human brain

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Three-dimensional structure of a complex of E2020 with acetylcholinesterase from Torpedo californica

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

VMD: visual molecular dynamics

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Asp7O in the peripheral anionic site of human butyrylcholinesterase

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Site of fasciculin interaction with acetylcholinesterase

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Allosteric Control of Acetylcholinesterase Catalysis by Fasciculin

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Amyloid plaque core protein in Alzheimer disease and Down syndrome

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

Mechanism of inhibition of cholinesterases by huperzine A

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6681301

23 February 2021

Identifiers

DOI

10.3390/PLANTS8070231

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31319560%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31319560%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

PubMed publication ID

31319560

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31319560%20AND%20SRC:MED&resulttype=core&format=json