-254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-κB Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children (Q91692922)

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scientific article published on 10 June 2019

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English	-254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-κB Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children	scientific article published on 10 June 2019

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scholarly article

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Europe PubMed Central

PMC publication ID

6590578

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

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24 April 2020

title

-254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-κB Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children (English)

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Europe PubMed Central

PMC publication ID

6590578

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

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24 April 2020

main subject

nephrotic syndrome

1 reference

based on heuristic

inferred from title

NF-κB

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based on heuristic

inferred from title

author

Xinyu Kuang

series ordinal

1

1 reference

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Europe PubMed Central

PMC publication ID

6590578

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

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24 April 2020

Qian Zhou

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2

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Europe PubMed Central

PMC publication ID

6590578

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

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24 April 2020

Wenyan Huang

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6

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Europe PubMed Central

PMC publication ID

6590578

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

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24 April 2020

author name string

Zhuying Li

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3

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Europe PubMed Central

PMC publication ID

6590578

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

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24 April 2020

Yujie Hu

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4

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Europe PubMed Central

PMC publication ID

6590578

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

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24 April 2020

Yulin Kang

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5

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Europe PubMed Central

PMC publication ID

6590578

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

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24 April 2020

publication date

10 June 2019

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6590578

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24 April 2020

published in

International Journal of Genomics

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Europe PubMed Central

PMC publication ID

6590578

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

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24 April 2020

volume

2019

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Europe PubMed Central

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6590578

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24 April 2020

page(s)

2197837

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6590578

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24 April 2020

copyright license

Creative Commons Attribution 4.0 International

start time

10 June 2019

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Analysis of 24 genes reveals a monogenic cause in 11.1% of cases with steroid-resistant nephrotic syndrome at a single center

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Spectrum of mutations in Chinese children with steroid-resistant nephrotic syndrome

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Role of renal TRP channels in physiology and pathology

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TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases

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A mutation in TRPC6 channels abolishes their activation by hypoosmotic stretch but does not affect activation by diacylglycerol or G protein signaling cascades

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23 February 2021

254C>G: a TRPC6 promoter variation associated with enhanced transcription and steroid-resistant nephrotic syndrome in Chinese children

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23 February 2021

TRPC6 mutations in children with steroid-resistant nephrotic syndrome and atypical phenotype.

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A novel TRPC6 mutation that causes childhood FSGS.

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TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription.

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Identifiers

DOI

10.1155/2019/2197837

1 reference

stated in

Europe PubMed Central

PMC publication ID

6590578

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

retrieved

24 April 2020

PMC publication ID

6590578

1 reference

stated in

Europe PubMed Central

PMC publication ID

6590578

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

retrieved

24 April 2020

PubMed publication ID

31281825

1 reference

stated in

Europe PubMed Central

PMC publication ID

6590578

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31281825%20AND%20SRC:MED&resulttype=core&format=json

retrieved

24 April 2020

 

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