Disuse-induced insulin resistance susceptibility coincides with a dysregulated skeletal muscle metabolic transcriptome (Q91577544)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30763167%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

title

Disuse-induced insulin resistance susceptibility coincides with a dysregulated skeletal muscle metabolic transcriptome (English)

1 reference

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23 April 2020

1 reference

1 reference

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15 May 2020

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15 May 2020

Paul T Reidy

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15 May 2020

Alec I McKenzie

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15 May 2020

Chris Stubben

series ordinal

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15 May 2020

Michael T Howard

series ordinal

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15 May 2020

publication date

14 February 2019

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Journal of Applied Physiology

23 April 2020

published in

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15 May 2020

volume

126

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15 May 2020

issue

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15 May 2020

page(s)

1419-1429

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Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males

15 May 2020

cites work

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Responses of skeletal muscle size and anabolism are reproducible with multiple periods of unloading/reloading

23 February 2021

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The impact of immobilisation and inflammation on the regulation of muscle mass and insulin resistance: different routes to similar end-points

23 February 2021

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Training-Induced Changes in Mitochondrial Content and Respiratory Function in Human Skeletal Muscle

23 February 2021

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Exercise recovery increases skeletal muscle H2O2 emission and mitochondrial respiratory capacity following two-weeks of limb immobilization

23 February 2021

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Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

23 February 2021

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23 February 2021

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Intramyocellular Lipid Droplet Size Rather Than Total Lipid Content is Related to Insulin Sensitivity After 8 Weeks of Overfeeding.

23 February 2021

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Branched-chain amino acid catabolism rather than amino acids plasma concentrations is associated with diet-induced changes in insulin resistance in overweight to obese individuals

23 February 2021

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Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults.

23 February 2021

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23 February 2021

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Neuromuscular Electrical Stimulation Combined with Protein Ingestion Preserves Thigh Muscle Mass But Not Muscle Function in Healthy Older Adults During 5 Days of Bed Rest

23 February 2021

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Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes

23 February 2021

1 reference

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Metabolic Profiling of Total Physical Activity and Sedentary Behavior in Community-Dwelling Men.

23 February 2021

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Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism

23 February 2021

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The epigenetic signature of systemic insulin resistance in obese women

23 February 2021

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Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export

23 February 2021

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One Week of Bed Rest Leads to Substantial Muscle Atrophy and Induces Whole-Body Insulin Resistance in the Absence of Skeletal Muscle Lipid Accumulation.

23 February 2021

1 reference

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MultiQC: summarize analysis results for multiple tools and samples in a single report.

23 February 2021

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Muscle Disuse as a Pivotal Problem in Sarcopenia-related Muscle Loss and Dysfunction.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6589819

23 February 2021

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HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages

23 February 2021

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Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6589819

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6589819

Skeletal muscle apolipoprotein B expression reduces muscular triglyceride accumulation

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6589819

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

23 February 2021

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PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

23 February 2021

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Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling.

23 February 2021

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Long-term leisure-time physical activity and serum metabolome

23 February 2021

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23 February 2021

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Expression of genes involved in fatty acid transport and insulin signaling is altered by physical inactivity and exercise training in human skeletal muscle

23 February 2021

1 reference

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Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses.

23 February 2021

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Physical inactivity as the culprit of metabolic inflexibility: evidence from bed-rest studies

23 February 2021

1 reference

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Metabolic disruptions induced by reduced ambulatory activity in free-living humans

23 February 2021

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Lack of regular physical exercise or too much inactivity

23 February 2021

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Cooperation of adenosine with macrophage Toll-4 receptor agonists leads to increased glycolytic flux through the enhanced expression of PFKFB3 gene.

23 February 2021

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23 February 2021

1 reference

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23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6589819

Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men.

23 February 2021

1 reference

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23 February 2021

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23 February 2021

1 reference

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23 February 2021

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23 February 2021

1 reference

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

1 reference

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Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6589819

Bed-rest-induced insulin resistance occurs primarily in muscle

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6589819

10.1152/JAPPLPHYSIOL.01093.2018

23 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6589819&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6589819&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6589819&resulttype=core&format=json