Atoh1 and other related key regulators in the development of auditory sensory epithelium in the mammalian inner ear: function and interplay (Q90864973)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

title

Atoh1 and other related key regulators in the development of auditory sensory epithelium in the mammalian inner ear: function and interplay (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

Chao Zhong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

Yong Fu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

Wen Pan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

Jun Yu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

Jinfu Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

publication date

31 December 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

number of pages

1 reference

based on heuristic

inferred from page(s)

published in

Developmental Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

volume

446

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

page(s)

133-141

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

Selection of cell fate in the organ of Corti involves the integration of Hes/Hey signaling at the Atoh1 promoter

17 April 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Hair cell regeneration after ATOH1 gene therapy in the cochlea of profoundly deaf adult guinea pigs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Sensory hair cell development and regeneration: similarities and differences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

From placode to polarization: new tunes in inner ear development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Math1: an essential gene for the generation of inner ear hair cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Auditory ganglion source of Sonic hedgehog regulates timing of cell cycle exit and differentiation of mammalian cochlear hair cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Atoh1 expression defines activated progenitors and differentiating hair cells during avian hair cell regeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Atoh1 directs hair cell differentiation and survival in the late embryonic mouse inner ear.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Regeneration of sensory hair cells after acoustic trauma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Atoh1 in sensory hair cell development: constraints and cofactors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Generation of sensory hair cells by genetic programming with a combination of transcription factors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Transcription factor induced conversion of human fibroblasts towards the hair cell lineage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Hair cells and supporting cells share a common progenitor in the avian inner ear.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Response of the flat cochlear epithelium to forced expression of Atoh1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Opportunities and limits of the one gene approach: the ability of Atoh1 to differentiate and maintain hair cells depends on the molecular context

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Regulation of cell fate in the sensory epithelia of the inner ear.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Sox2 in the differentiation of cochlear progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Notch signalling pathway mediates hair cell development in mammalian cochlea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Atoh1 as a Coordinator of Sensory Hair Cell Development and Regeneration in the Cochlea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

A morphogenetic wave of p27Kip1 transcription directs cell cycle exit during organ of Corti development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

In vivo generation of immature inner hair cells in neonatal mouse cochleae by ectopic Atoh1 expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Regulation of POU4F3 gene expression in hair cells by 5' DNA in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

TFE2 and GATA3 enhance induction of POU4F3 and myosin VIIa positive cells in nonsensory cochlear epithelium by ATOH1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Atoh1, an essential transcription factor in neurogenesis and intestinal and inner ear development: function, regulation, and context dependency.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

The prosensory function of Sox2 in the chicken inner ear relies on the direct regulation of Atoh1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Extensive Supporting Cell Proliferation and Mitotic Hair Cell Generation by In Vivo Genetic Reprogramming in the Neonatal Mouse Cochlea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Induction of inner ear hair cell-like cells from Math1-transfected mouse ES cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

A novel Atoh1 "self-terminating" mouse model reveals the necessity of proper Atoh1 level and duration for hair cell differentiation and viability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Computational analysis of mRNA expression profiling in the inner ear reveals candidate transcription factors associated with proliferation, differentiation, and deafness.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Regeneration of Sensory Hair Cells Requires Localized Interactions between the Notch and Wnt Pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Hair cell regeneration after acoustic trauma in adult Coturnix quail

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Commissural neuron identity is specified by a homeodomain protein, Mbh1, that is directly downstream of Math1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Distinct population of hair cell progenitors can be isolated from the postnatal mouse cochlea using side population analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Gene Expression by Mouse Inner Ear Hair Cells during Development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Epigenetic regulation of Atoh1 guides hair cell development in the mammalian cochlea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Hair cell regeneration in the avian auditory epithelium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Multiple roles of Notch signaling in cochlear development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Therapeutic potential of a gamma-secretase inhibitor for hearing restoration in a guinea pig model with noise-induced hearing loss

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Regulation of the orphan nuclear receptor Nr2f2 by the DFNA15 deafness gene Pou4f3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Inner ear supporting cells: rethinking the silent majority.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Math1 regulates development of the sensory epithelium in the mammalian cochlea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Essential role of POU–domain factor Brn-3c in auditory and vestibular hair cell development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Regeneration of stereocilia of hair cells by forced Atoh1 expression in the adult mammalian cochlea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Six1 is essential for differentiation and patterning of the mammalian auditory sensory epithelium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Barhl1 is required for the differentiation of inner ear hair cell-like cells from mouse embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

The spontaneous appearance of hair cell-like cells in the mammalian cochlea following aminoglycoside ototoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2018.12.025

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YDBIO.2018.12.025

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json

17 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30605626%20AND%20SRC:MED&resulttype=core&format=json