Schizandrin Protects against OGD/R-Induced Neuronal Injury by Suppressing Autophagy: Involvement of the AMPK/mTOR Pathway (Q90613964)

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scientific article published on 08 October 2019

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English	Schizandrin Protects against OGD/R-Induced Neuronal Injury by Suppressing Autophagy: Involvement of the AMPK/mTOR Pathway	scientific article published on 08 October 2019

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scholarly article

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Europe PubMed Central

PMC publication ID

6804185

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31597329%20AND%20SRC:MED&resulttype=core&format=json

retrieved

15 April 2020

title

Schizandrin Protects against OGD/R-Induced Neuronal Injury by Suppressing Autophagy: Involvement of the AMPK/mTOR Pathway (English)

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stated in

Europe PubMed Central

PMC publication ID

6804185

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31597329%20AND%20SRC:MED&resulttype=core&format=json

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15 April 2020

main subject

autophagy

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author

Boyang Yu

series ordinal

5

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Europe PubMed Central

PMC publication ID

6804185

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31597329%20AND%20SRC:MED&resulttype=core&format=json

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15 April 2020

Junping Kou

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6

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Europe PubMed Central

PMC publication ID

6804185

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31597329%20AND%20SRC:MED&resulttype=core&format=json

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15 April 2020

author name string

Guangyun Wang

series ordinal

1

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Europe PubMed Central

PMC publication ID

6804185

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31597329%20AND%20SRC:MED&resulttype=core&format=json

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15 April 2020

Tiezheng Wang

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2

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Europe PubMed Central

PMC publication ID

6804185

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31597329%20AND%20SRC:MED&resulttype=core&format=json

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15 April 2020

Yuanyuan Zhang

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3

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Europe PubMed Central

PMC publication ID

6804185

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31597329%20AND%20SRC:MED&resulttype=core&format=json

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15 April 2020

Fang Li

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4

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Europe PubMed Central

PMC publication ID

6804185

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publication date

8 October 2019

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Europe PubMed Central

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6804185

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15 April 2020

published in

Molecules

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PMC publication ID

6804185

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15 April 2020

volume

24

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Europe PubMed Central

PMC publication ID

6804185

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15 April 2020

issue

19

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Europe PubMed Central

PMC publication ID

6804185

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15 April 2020

copyright license

Creative Commons Attribution 4.0 International

start time

8 October 2019

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April 2022 Public Data File from Crossref

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cites work

Oxygen sensing in neuroendocrine cells and other cell types: pheochromocytoma (PC12) cells as an experimental model

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Dibenzocyclooctadiene lignans from Schisandra chinensis protect primary cultures of rat cortical cells from glutamate-induced toxicity

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Autophagy and its possible roles in nervous system diseases, damage and repair

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PubMed

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12 December 2020

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Transport of autophagosomes in neurites of PC12 cells during serum deprivation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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A combination of four active compounds alleviates cerebral ischemia-reperfusion injury in correlation with inhibition of autophagy and modulation of AMPK/mTOR and JNK pathways

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage

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12 December 2020

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Neuroprotective effect of schizandrin A on oxygen and glucose deprivation/reperfusion-induced cell injury in primary culture of rat cortical neurons

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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The protective mechanism of schisandrin A in d-galactosamine-induced acute liver injury through activation of autophagy

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12 December 2020

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Autophagy: an emerging therapeutic target in vascular diseases

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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mTOR: a pharmacologic target for autophagy regulation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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Protection of seven dibenzocyclooctadiene lignans from Schisandra chinensis against serum and glucose deprivation injury in SH-SY5Y cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

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Schisandrin B Ameliorates ICV-Infused Amyloid β Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-κB/MAPK and Up-Regulating HSP/Beclin Expression.

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Synergistic Use of Geniposide and Ginsenoside Rg1 Balance Microglial TNF-α and TGF-β1 following Oxygen-Glucose Deprivation In Vitro: A Genome-Wide Survey

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

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12 December 2020

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Schizandrin A Inhibits Microglia-Mediated Neuroninflammation through Inhibiting TRAF6-NF-κB and Jak2-Stat3 Signaling Pathways

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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Shengmai injection attenuates the cerebral ischemia/reperfusion induced autophagy via modulation of the AMPK, mTOR and JNK pathways

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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Inhibition of AMP-activated protein kinase alleviates focal cerebral ischemia injury in mice: Interference with mTOR and autophagy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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Breviscapine confers a neuroprotective efficacy against transient focal cerebral ischemia by attenuating neuronal and astrocytic autophagy in the penumbra

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

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Sirt3 confers protection against neuronal ischemia by inducing autophagy: Involvement of the AMPK-mTOR pathway

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of cyclosporine A induced nephrotoxicity by schisandrin B through suppression of oxidative stress, apoptosis and autophagy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

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PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An overview of neuroprotective and cognitive enhancement properties of lignans from Schisandra chinensis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schisandrin C enhances mitochondrial biogenesis and autophagy in C2C12 skeletal muscle cells: potential involvement of anti-oxidative mechanisms

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

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inferred from PubMed ID database lookup

Effects of thymosin β4 on oxygen‑glucose deprivation and reoxygenation‑induced injury

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

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Autophagy in ischemic stroke

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schisandrin C enhances odontoblastic differentiation through autophagy and mitochondrial biogenesis in human dental pulp cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitexin reverses the autophagy dysfunction to attenuate MCAO-induced cerebral ischemic stroke via mTOR/Ulk1 pathway

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Puerarin protects rat brain against ischemia/reperfusion injury by suppressing autophagy via the AMPK-mTOR-ULK1 signaling pathway

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schizandrin A Alleviates LPS-Induced Injury in Human Keratinocyte Cell Hacat Through a MicroRNA-127-Dependent Regulation

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

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Prevention of stroke: a global perspective

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TREK-2 mediates the neuroprotective effect of isoflurane preconditioning against acute cerebral ischemia in the rat

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Propofol inhibited autophagy through Ca/CaMKKβ/AMPK/mTOR pathway in OGD/R-induced neuron injury

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy and the cell biology of age-related disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schizandrin A protects against cerebral ischemia-reperfusion injury by suppressing inflammation and oxidative stress and regulating the AMPK/Nrf2 pathway regulation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schizandrin A supplementation improves nonalcoholic fatty liver disease in mice fed a high-fat and high-cholesterol diet

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel therapeutic strategies for stroke: The role of autophagy

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schizandrin A inhibits proliferation, migration and invasion of thyroid cancer cell line TPC-1 by down regulation of microRNA-429

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KCNQ1OT1 promotes autophagy by regulating miR-200a/FOXO3/ATG7 pathway in cerebral ischemic stroke.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TIGAR alleviates ischemia/reperfusion-induced autophagy and ischemic brain injury

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuroprotective effects of curcumin are associated with the regulation of the reciprocal function between autophagy and HIF-1α in cerebral ischemia-reperfusion injury

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of GPR37 via regulation of inflammation and multiple cell death pathways after ischemic stroke in mice

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31597329

retrieved

12 December 2020

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Identifiers

DOI

10.3390/MOLECULES24193624

1 reference

stated in

Europe PubMed Central

PMC publication ID

6804185

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31597329%20AND%20SRC:MED&resulttype=core&format=json

retrieved

15 April 2020

PMC publication ID

6804185

1 reference

stated in

Europe PubMed Central

PMC publication ID

6804185

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31597329%20AND%20SRC:MED&resulttype=core&format=json

retrieved

15 April 2020

PubMed publication ID

31597329

1 reference

stated in

Europe PubMed Central

PMC publication ID

6804185

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31597329%20AND%20SRC:MED&resulttype=core&format=json

retrieved

15 April 2020

 

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