T-Cell Proapoptotic and Antifibrotic Activity Against Autologous Skin Fibroblasts in vitro Is Associated With IL-17A Axis Upregulation in Systemic Sclerosis (Q90345176)

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scientific article published on 27 February 2020

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English	T-Cell Proapoptotic and Antifibrotic Activity Against Autologous Skin Fibroblasts in vitro Is Associated With IL-17A Axis Upregulation in Systemic Sclerosis	scientific article published on 27 February 2020

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scholarly article

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13 April 2020

T-Cell Proapoptotic and Antifibrotic Activity Against Autologous Skin Fibroblasts in vitro Is Associated With IL-17A Axis Upregulation in Systemic Sclerosis (English)

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13 April 2020

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Serena Vettori

1

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13 April 2020

Giusi Barra

2

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13 April 2020

Barbara Russo

3

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13 April 2020

Alessia Borgia

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13 April 2020

Giuseppe Pasquale

5

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13 April 2020

Luciana Pellecchia

6

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13 April 2020

Lucia Vicedomini

7

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13 April 2020

Raffaele De Palma

8

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13 April 2020

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27 February 2020

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13 April 2020

Frontiers in Immunology

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13 April 2020

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13 April 2020

220

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13 April 2020

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Creative Commons Attribution 4.0 International

27 February 2020

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April 2022 Public Data File from Crossref

copyright status

0 references

Scleroderma (systemic sclerosis): classification, subsets and pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human IL-17: a novel cytokine derived from T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The IL-2 receptor complex: its structure, function, and target genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Product differentiation by analysis of DNA melting curves during the polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of type I collagen production by dermal fibroblasts upon contact with activated T cells: different sensitivity to inhibition between systemic sclerosis and control fibroblasts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased interleukin-17 production in patients with systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligoclonal T cell expansion in the skin of patients with systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human gamma delta-T lymphocytes express and synthesize connective tissue growth factor: effect of IL-15 and TGF-beta 1 and comparison with alpha beta-T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and synthesis of fibroblast growth factor-9 in human gammadelta T-lymphocytes. Response to isopentenyl pyrophosphate and TGF-beta1/IL-15.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Connective tissue growth factor causes persistent proalpha2(I) collagen gene expression induced by transforming growth factor-beta in a mouse fibrosis model

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral T lymphocytes from patients with early systemic sclerosis co-cultured with autologous fibroblasts undergo an oligoclonal expansion similar to that occurring in the skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analyzing real-time PCR data by the comparative C(T) method

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T cells ameliorate angiotensin II-induced cardiac damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vgamma9+ gammadelta T cells in systemic sclerosis patients are numerically and functionally preserved and induce fibroblast apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of tissue fibrosis in skin biopsies from patients with systemic sclerosis employing confocal laser scanning microscopy: an objective outcome measure for clinical trials?

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral T cells from patients with early systemic sclerosis kill autologous fibroblasts in co-culture: is T-cell response aimed to play a protective role?

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Survival and death causes in 251 systemic sclerosis patients from a single Italian center]

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EUSTAR biobanking: recommendations for the collection, storage and distribution of biospecimens in scleroderma research

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered T-cell and regulatory cell repertoire in patients with diffuse cutaneous systemic sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of Th17 and Treg cell subpopulations co-exist in patients affected with systemic sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and -independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired IL-17 signaling pathway contributes to the increased collagen expression in scleroderma fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential roles of interleukin-17A in the development of skin fibrosis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered Th17 cells and Th17/regulatory T-cell ratios indicate the subsequent conversion from undifferentiated connective tissue disease to definitive systemic autoimmune disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-17 family: cytokines, receptors and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th17 cells favor inflammatory responses while inhibiting type I collagen deposition by dermal fibroblasts: differential effects in healthy and systemic sclerosis fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early Systemic Sclerosis: Serum Profiling of Factors Involved in Endothelial, T-cell, and Fibroblast Interplay is Marked by Elevated Interleukin-33 Levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High IL-17E and low IL-17C dermal expression identifies a fibrosis-specific motif common to morphea and systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the acquired immune response in systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 17, Produced by γδ T Cells, Contributes to Hepatic Inflammation in a Mouse Model of Biliary Atresia and Is Increased in Livers of Patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th17 cells and IL-17 promote the skin and lung inflammation and fibrosis process in a bleomycin-induced murine model of systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of CD8+ T Cells Exacerbates CD4+ T Cell-Induced Monocyte-to-Fibroblast Transition in Renal Fibrosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic sclerosis: An update in 2016.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expanding antigen-specific regulatory networks to treat autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-17A mediates cardiomyocyte apoptosis through Stat3-iNOS pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-17A weakens the antitumor immuity by inhibiting apoptosis of MDSCs in Lewis lung carcinoma bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-17-mediated mitochondrial dysfunction impairs apoptosis in rheumatoid arthritis synovial fibroblasts through activation of autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is there a role for IL-17 in the pathogenesis of systemic sclerosis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interleukin 17 in TGF-β signaling-mediated renal interstitial fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1-IL-17 Signaling Axis Contributes to Fibrosis and Inflammation in Two Different Murine Models of Systemic Sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 and Type-I Collagen Production by Systemic Sclerosis Fibroblasts Are Differentially Regulated by Interleukin-17A in the Presence of Transforming Growth Factor-Beta 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/32174912

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FIMMU.2020.00220

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32174912%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32174912%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32174912%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

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