Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency (Q90339516)

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scientific article published on 16 March 2020

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English	Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency	scientific article published on 16 March 2020

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32173907%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32173907%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

author name string

Fan Yang

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32173907%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Hongwei Ma

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32173907%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Michael R Butler

3

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Europe PubMed Central

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13 April 2020

Xi-Qin Ding

4

1 reference

Europe PubMed Central

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13 April 2020

publication date

16 March 2020

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32173907%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32173907%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the Cardiac Ryanodine Receptor by Protein Kinase-Dependent Phosphorylation1

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the cardiac ryanodine receptor by cAMP-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total colourblindness is caused by mutations in the gene encoding the alpha-subunit of the cone photoreceptor cGMP-gated cation channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of a retinal guanylyl cyclase gene leads to cone-specific dystrophy and paradoxical rod behavior.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide signaling contributes to late-phase LTP and CREB phosphorylation in the hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the CNGB3 gene encoding the beta-subunit of the cone photoreceptor cGMP-gated channel are responsible for achromatopsia (ACHM3) linked to chromosome 8q21.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB is cleaved by caspases during neural cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and induces apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrl is required for rod photoreceptor development

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic nucleotide-gated ion channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ryanodine receptor calcium release channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide regulates cGMP-dependent cAMP-responsive element binding protein phosphorylation and Bcl-2 expression in cerebellar neurons: implication for a survival role of nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective phosphorylation of the IP3R-I in vivo by cGMP-dependent protein kinase in smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ryanodine stores and calcium regulation in the inner segments of salamander rods and cones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate induces phosphorylation of cAMP response element (CRE)-binding protein and increases DNA-binding activity of CRE in rat retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What turns CREB on?

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted expression of Cre recombinase to cone photoreceptors in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum calcium signaling in nerve cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cone cGMP-gated channel mutations and clinical findings in patients with achromatopsia, macular degeneration, and other hereditary cone diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoreceptors of Nrl -/- mice coexpress functional S- and M-cone opsins having distinct inactivation mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired opsin targeting and cone photoreceptor migration in the retina of mice lacking the cyclic nucleotide-gated channel CNGA3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ryanodine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inositol 1,4,5-trisphosphate receptor type 1 phosphorylation and regulation by extracellular signal-regulated kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SERCA pump isoforms: their role in calcium transport and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C decreases the apparent affinity of the inositol 1,4,5-trisphosphate receptor type 3 in RINm5F cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C phosphorylates the inositol 1,4,5-trisphosphate receptor type 2 and decreases the mobilization of Ca2+in pancreatoma AR4-2J cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optical coherence tomography of the macula in congenital achromatopsia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of novel retinal target genes of thyroid hormone in the human WERI cells by expression microarray analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive excitation by Gly90Asp rhodopsin rescues rods from degeneration caused by elevated production of cGMP in the dark.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intact beta-adrenergic response and unmodified progression toward heart failure in mice with genetic ablation of a major protein kinase A phosphorylation site in the cardiac ryanodine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retina expresses a novel variant of the ryanodine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Native cone photoreceptor cyclic nucleotide-gated channel is a heterotetrameric complex comprising both CNGA3 and CNGB3: a study using the cone-dominant retina of Nrl-/- mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic etiology and clinical consequences of complete and incomplete achromatopsia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB1/ATF1 activation in photoreceptor degeneration and protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired cone function and cone degeneration resulting from CNGB3 deficiency: down-regulation of CNGA3 biosynthesis as a potential mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of intracellular calcium signaling as a neuroprotective strategy

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive loss of cones in achromatopsia: an imaging study using spectral-domain optical coherence tomography.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IP(3) receptors: toward understanding their activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early-onset, slow progression of cone photoreceptor dysfunction and degeneration in CNG channel subunit CNGB3 deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic-reticulum calcium depletion and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of ryanodine receptor Ca2+ channels (Review).

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoreceptor structure and function in patients with congenital achromatopsia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization and phenotype-specific expression of ryanodine calcium release channels in C57BL6 and DBA/2J mouse strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ store depletion and endoplasmic reticulum stress are involved in P2X7 receptor-mediated neurotoxicity in differentiated NG108-15 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective modulation of subtype III IP₃R by Akt regulates ER Ca²⁺ release and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB-binding protein (CBP) regulates β-adrenoceptor (β-AR)-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnostic fundus autofluorescence patterns in achromatopsia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cGMP-Dependent Protein Kinase Inhibitors in Health and Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectral domain optical coherence tomography findings in CNGB3-associated achromatopsia and therapeutic implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of CREB protein protects from tunicamycin-induced apoptosis in various rat cell types.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel CNGA3 mutations in Chinese patients with achromatopsia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium release channel RyR2 regulates insulin release and glucose homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB is activated by ER stress and modulates the unfolded protein response by regulating the expression of IRE1α and PERK.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced phosphoCREB in Müller glia during retinal degeneration in rd10 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal Cyclic Nucleotide-Gated Channels: From Pathophysiology to Therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum stress induces spatial memory deficits by activating GSK-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ER Stress, CREB, and Memory: A Tangled Emerging Link in Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pivotal role of cAMP-PKA-CREB signaling pathway in manganese-induced neurotoxicity in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ryanodine Receptor 2 Contributes to Impaired Protein Localization in Cyclic Nucleotide-Gated Channel Deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/32173907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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