Small-Molecule Inhibition of Glucose Transporters GLUT-1-4 (Q90278398)

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scientific article published on 08 November 2019

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English	Small-Molecule Inhibition of Glucose Transporters GLUT-1-4	scientific article published on 08 November 2019

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scholarly article

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Europe PubMed Central

PMC publication ID

7004114

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

review article

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Europe PubMed Central

title

Small-Molecule Inhibition of Glucose Transporters GLUT-1-4 (English)

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stated in

Europe PubMed Central

PMC publication ID

7004114

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

author

Herbert Waldmann

series ordinal

2

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stated in

Europe PubMed Central

PMC publication ID

7004114

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

author name string

Elena S Reckzeh

series ordinal

1

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stated in

Europe PubMed Central

PMC publication ID

7004114

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

publication date

8 November 2019

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stated in

Europe PubMed Central

PMC publication ID

7004114

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

published in

ChemBioChem

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stated in

Europe PubMed Central

PMC publication ID

7004114

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

volume

21

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stated in

Europe PubMed Central

PMC publication ID

7004114

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

issue

1-2

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stated in

Europe PubMed Central

PMC publication ID

7004114

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

page(s)

45-52

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Europe PubMed Central

PMC publication ID

7004114

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

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Positron emission tomography with 2-[18F]Fluoro-2-deoxy-D-glucose and 16alpha-[18F]fluoro-17beta-estradiol in breast cancer: correlation with estrogen receptor status and response to systemic therapy

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Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine

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Chlamydia pneumoniae directly interferes with HIF-1alpha stabilization in human host cells.

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Functional properties and genomics of glucose transporters

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12 December 2020

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

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12 December 2020

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Noninvasive pulmonary [18F]-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment

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12 December 2020

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Novel inhibitors of basal glucose transport as potential anticancer agents

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12 December 2020

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GLUT1 and GLUT3 as potential prognostic markers for Oral Squamous Cell Carcinoma

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12 December 2020

based on heuristic

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Potential role of sugar transporters in cancer and their relationship with anticancer therapy

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https://pubmed.ncbi.nlm.nih.gov/31553512

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12 December 2020

based on heuristic

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Nutrient Transport and Pathogenesis in Selected Parasitic Protozoa

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12 December 2020

based on heuristic

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Metabolic profiling of lung granuloma in Mycobacterium tuberculosis infected guinea pigs: ex vivo 1H magic angle spinning NMR studies

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https://pubmed.ncbi.nlm.nih.gov/31553512

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31553512

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting cancer metabolism: a therapeutic window opens

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31553512

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of GLUT1 and GLUT3 glucose transporters in endometrial and breast cancers.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31553512

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31553512

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of hypoxia-related glucose transporters GLUT1 and GLUT3 in benign, malignant and non-neoplastic thyroid lesions

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/31553512

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of TGF-β Receptors in Fibrosis

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of PFKFB3-driven glycolysis in vessel sprouting

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https://pubmed.ncbi.nlm.nih.gov/31553512

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling cancer glycolysis under hypoglycemia, and the role played by the differential expression of glycolytic isoforms.

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycolysis in patients with age-related macular degeneration

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming 5-Fu resistance of colon cells through inhibition of Glut1 by the specific inhibitor WZB117.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor suppressor p53 alters host cell metabolism to limit Chlamydia trachomatis infection

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-dependent glucose transporter 1 expression and its impact on viability of thyroid cancer cells

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/31553512

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normalization of CD4+ T cell metabolism reverses lupus

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by interferon-γ.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose transporter isoform 1 expression enhances metastasis of malignant melanoma cells

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infection with Mycobacterium tuberculosis induces the Warburg effect in mouse lungs

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12 December 2020

based on heuristic

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Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment

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12 December 2020

based on heuristic

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The Warburg Effect: How Does it Benefit Cancer Cells?

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting Edge: Mycobacterium tuberculosis Induces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication

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based on heuristic

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Identification of novel GLUT inhibitors

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Inhibition of Glut1 by WZB117 sensitizes radioresistant breast cancer cells to irradiation

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Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides

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Glucose Metabolism in T Cells and Monocytes: New Perspectives in HIV Pathogenesis

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Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer

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Fundamentals of cancer metabolism

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12 December 2020

based on heuristic

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Profibrotic up-regulation of glucose transporter 1 by TGF-β involves activation of MEK and mammalian target of rapamycin complex 2 pathways.

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Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876.

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Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells

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12 December 2020

based on heuristic

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WZB117 (2-Fluoro-6-(m-hydroxybenzoyloxy) Phenyl m-Hydroxybenzoate) Inhibits GLUT1-mediated Sugar Transport by Binding Reversibly at the Exofacial Sugar Binding Site

1 reference

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Anticancer agents interacting with membrane glucose transporters

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brucella abortus Induces a Warburg Shift in Host Metabolism That Is Linked to Enhanced Intracellular Survival of the Pathogen

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of GLUT1 by WZB117 resensitizes breast cancer cells to adriamycin

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages

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12 December 2020

based on heuristic

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SLC2A2 (GLUT2) as a novel prognostic factor for hepatocellular carcinoma

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12 December 2020

based on heuristic

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Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients with Type 1 Diabetes

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive Oxygen Species-Mediated Tumor Microenvironment Transformation: The Mechanism of Radioresistant Gastric Cancer.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting Key Transporters in Tumor Glycolysis as a Novel Anticancer Strategy

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quercetin inhibits glucose transport by binding to an exofacial site on GLUT1

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of antimelanoma effect of oat β-glucan supported by electroporation

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting glucose transport and the NAD pathway in tumor cells with STF-31: a re-evaluation

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of GLUTs by WZB117 mediates apoptosis in blood-stage Plasmodium parasites by breaking redox balance

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rhinovirus induces an anabolic reprogramming in host cell metabolism essential for viral replication

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation of glucose transporter 1 in orthodontic tooth movement-associated mechanical response

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromopynones are pseudo natural product glucose uptake inhibitors targeting glucose transporters GLUT-1 and -3

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting ulcerative colitis by suppressing glucose uptake with ritonavir

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of cellular reactive oxygen species in cancer chemotherapy

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-enriched solute carrier family 2 member 1 (SLC2A1/GLUT1) in psoriatic keratinocytes confers sensitivity to 2-deoxy-D-glucose (2-DG) treatment

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of glucose transporter 1 activity inhibition on neuroblastoma in vitro

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose transporter 1 regulates the proliferation and cisplatin sensitivity of esophageal cancer

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of glucose metabolism is important in tenogenic differentiation of progenitors derived from human injured tendons

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A chemical toolbox for the study of bromodomains and epigenetic signaling

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose Transporters

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The combination of the glycolysis inhibitor 2-DG and sorafenib can be effective against sorafenib-tolerant persister cancer cells

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https://pubmed.ncbi.nlm.nih.gov/31553512

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of Indomorphan Pseudo-Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/31553512

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1002/CBIC.201900544

1 reference

stated in

Europe PubMed Central

PMC publication ID

7004114

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

PMC publication ID

7004114

1 reference

stated in

Europe PubMed Central

PMC publication ID

7004114

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

PubMed publication ID

31553512

1 reference

stated in

Europe PubMed Central

PMC publication ID

7004114

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31553512%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 April 2020

 

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