Prolonged ursodeoxycholic acid administration reduces acute ischaemia-induced arrhythmias in adult rat hearts (Q99564897)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32943714%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

title

Prolonged ursodeoxycholic acid administration reduces acute ischaemia-induced arrhythmias in adult rat hearts (English)

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24 September 2020

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24 September 2020

Elisa Ferraro

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24 September 2020

Lidia Pozhidaeva

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24 September 2020

David S Pitcher

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24 September 2020

Catherine Mansfield

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24 September 2020

Jia Han Benjamin Koh

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24 September 2020

Catherine Williamson

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24 September 2020

Oleg Aslanidi

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24 September 2020

Julia Gorelik

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24 September 2020

publication date

17 September 2020

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24 September 2020

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24 September 2020

volume

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24 September 2020

issue

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24 September 2020

page(s)

15284

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24 September 2020

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Electrical uncoupling and increase of extracellular resistance after induction of ischemia in isolated, arterially perfused rabbit papillary muscle.

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Dephosphorylation and intracellular redistribution of ventricular connexin43 during electrical uncoupling induced by ischemia

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Myocardial reperfusion injury.

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Mechanisms responsible for arrhythmias associated with reperfusion of ischemic myocardium

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Myocardial ischemia/reperfusion-injury, a clinical view on a complex pathophysiological process

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Ursodeoxycholic acid therapy in hepatobiliary disease

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The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases

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Bile acids in treatment of ocular disease

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Hydrophilic bile salt ursodeoxycholic acid protects myocardium against reperfusion injury in a PI3K/Akt dependent pathway

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7 January 2021

Effect of ursodeoxycholic acid on ischemia/reperfusion injury in isolated rat heart

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Ursodeoxycholic acid in patients with chronic heart failure: a double-blind, randomized, placebo-controlled, crossover trial.

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Dexamethasone and ursodeoxycholic acid protect against the arrhythmogenic effect of taurocholate in an in vitro study of rat cardiomyocytes

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7 January 2021

A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart

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7 January 2021

The protective effect of ursodeoxycholic acid in an in vitro model of the human fetal heart occurs via targeting cardiac fibroblasts.

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7 January 2021

Ursodeoxycholic acid prevents ventricular conduction slowing and arrhythmia by restoring T-type calcium current in fetuses during cholestasis

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7 January 2021

Two periods of early ventricular arrhythmia in the canine acute myocardial infarction model

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Characterisation, utilisation and clinical relevance of isolated perfused heart models of ischaemia-induced ventricular fibrillation

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The pathophysiology of malignant ventricular arrhythmias during acute myocardial ischemia

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Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver

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Selective heart rate reduction with ivabradine slows ischaemia-induced electrophysiological changes and reduces ischaemia-reperfusion-induced ventricular arrhythmias.

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7 January 2021

Failure of antiarrhythmic drugs to prevent experimental reperfusion ventricular fibrillation

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7 January 2021

Regulation of ion channels and arrhythmias in the ischemic heart

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7 January 2021

Transmural repolarisation in the left ventricle in humans during normoxia and ischaemia

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Inhomogeneous transmural conduction during early ischaemia in patients with coronary artery disease

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Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123).

1 reference

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7 January 2021

Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels

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7 January 2021

Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC.

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7 January 2021

Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart

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7 January 2021

The C-terminus of connexin43 adopts different conformations in the Golgi and gap junction as detected with structure-specific antibodies

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7 January 2021

Selectivity of connexin 43 channels is regulated through protein kinase C-dependent phosphorylation

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7 January 2021

Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size

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Altered connexin43 expression produces arrhythmia substrate in heart failure

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Taxol stabilizes gap junctions and reduces ischemic ventricular arrhythmias in rats in vivo

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Antiarrhythmic effect mediated by κ-opioid receptor is associated with Cx43 stabilization*

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7 January 2021

Reentrant and nonreentrant mechanisms contribute to arrhythmogenesis during early myocardial ischemia: results using three-dimensional mapping

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Ursodeoxycholic acid ameliorates fructose-induced metabolic syndrome in rats

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The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion

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Adverse remodeling of the electrophysiological response to ischemia-reperfusion in human heart failure is associated with remodeling of metabolic gene expression.

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7 January 2021

Enhancement of Gap Junction Function During Acute Myocardial Infarction Modifies Healing and Reduces Late Ventricular Arrhythmia Susceptibility.

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7 January 2021

Processing and analysis of cardiac optical mapping data obtained with potentiometric dyes

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Dynamical and cellular electrophysiological mechanisms of ECG changes during ischaemia.

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Changes in extracellular and intracellular pH in ischemic rabbit papillary muscle

1 reference

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7 January 2021

10.1038/S41598-020-72016-4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32943714%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32943714%20AND%20SRC:MED&resulttype=core&format=json