Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes (Q99412210)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32926233%20AND%20SRC:MED&resulttype=core&format=json

17 September 2020

title

Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes (English)

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17 September 2020

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17 September 2020

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17 September 2020

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17 September 2020

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17 September 2020

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17 September 2020

publication date

14 September 2020

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Journal of Biological Inorganic Chemistry

17 September 2020

published in

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Alkyne Functionalization of a Photoactivated Ruthenium Polypyridyl Complex for Click-Enabled Serum Albumin Interaction Studies

17 September 2020

cites work

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A Phase 1 Study of SLC-0111, a Novel Inhibitor of Carbonic Anhydrase IX, in Patients With Advanced Solid Tumors

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Perfluoroalkyl Substances of Significant Environmental Concern Can Strongly Inhibit Human Carbonic Anhydrase Isozymes

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Native Mass Spectrometry: What is in the Name?

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Native vs Denatured: An in Depth Investigation of Charge State and Isotope Distributions

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New anthranilic acid-incorporating N-benzenesulfonamidophthalimides as potent inhibitors of carbonic anhydrases I, II, IX, and XII: Synthesis, in vitro testing, and in silico assessment

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1 March 2021

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"To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation.

1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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Neutron structure of human carbonic anhydrase II in complex with methazolamide: mapping the solvent and hydrogen-bonding patterns of an effective clinical drug

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1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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Carbonic anhydrase inhibition and the management of neuropathic pain

1 March 2021

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Native State Mass Spectrometry, Surface Plasmon Resonance, and X-ray Crystallography Correlate Strongly as a Fragment Screening Combination

1 March 2021

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Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111

1 March 2021

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Conformational effects in protein electrospray-ionization mass spectrometry

1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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Carbonic anhydrase inhibitors. Regioselective synthesis of novel series 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII

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Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?

1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency

1 March 2021

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1 March 2021

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A Short, Strong Hydrogen Bond in the Active Site of Human Carbonic Anhydrase II

1 March 2021

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High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design

1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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1 March 2021

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Investigation of structure, dynamics and function of metalloproteins with electrospray ionization mass spectrometry

1 March 2021

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Applications of ESI-MS in drug discovery: interrogation of noncovalent complexes

1 March 2021

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Estimates of protein surface areas in solution by electrospray ionization mass spectrometry

1 March 2021

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Predicting inhibitory drug-drug interactions and evaluating drug interaction reports using inhibition constants

1 March 2021

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Investigation of intact protein complexes by mass spectrometry.

1 March 2021

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Mass spectrometric approaches using electrospray ionization charge states and hydrogen-deuterium exchange for determining protein structures and their conformational changes

1 March 2021

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Carbonic anhydrase inhibitors

1 March 2021

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Direct comparison of binding equilibrium, thermodynamic, and rate constants determined by surface- and solution-based biophysical methods

1 March 2021

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Early discovery drug screening using mass spectrometry

1 March 2021

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Analysis of noncovalent complexes of DNA and RNA by mass spectrometry

1 March 2021

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An electrospray ionization mass spectrometry investigation of 1-anilino-8-naphthalene-sulfonate (ANS) binding to proteins

1 March 2021

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Carbonic anhydrase inhibitors: aromatic sulfonamides and disulfonamides act as efficient tumor growth inhibitors

1 March 2021

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Probing the energetics of dissociation of carbonic anhydrase-ligand complexes in the gas phase.

1 March 2021

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Studying noncovalent protein complexes by electrospray ionization mass spectrometry

1 March 2021

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Structure and mechanism of carbonic anhydrase

1 March 2021

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Acid-Induced Unfolding of Cytochrome c at Different Methanol Concentrations: Electrospray Ionization Mass Spectrometry Specifically Monitors Changes in the Tertiary Structure

1 March 2021

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A novel biologically active seleno-organic compound—1

1 March 2021

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Nuclear magnetic resonance studies of human carbonic anhydrase B. Histidine residues

1 March 2021

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Human carbonic anhydrase. Protein conformation and metal ion binding

1 March 2021

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Stopped flow mass spectrometry: applications to the carbonic anhydrase reaction

1 March 2021

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NMR studies of carbonic anhydrase-fluorinated benzenesulfonamide complexes

1 March 2021

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Transfer of oxygen from an artificial protease to peptide carbon during proteolysis

1 March 2021

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Paramagnetic and Fluorescent Probes Attached to "Buried" Sulfhydryl Groups in Human Carbonic Anhydrases. Application to Inhibitor Binding, Denaturation and Refolding

1 March 2021

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