CD146, from a melanoma cell adhesion molecule to a signaling receptor (Q98386021)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32782280%20AND%20SRC:MED&resulttype=core&format=json

14 August 2020

title

CD146, from a melanoma cell adhesion molecule to a signaling receptor (English)

1 reference

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14 August 2020

1 reference

Zhaoqing Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32782280%20AND%20SRC:MED&resulttype=core&format=json

14 August 2020

Qingji Xu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32782280%20AND%20SRC:MED&resulttype=core&format=json

14 August 2020

Nengwei Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32782280%20AND%20SRC:MED&resulttype=core&format=json

14 August 2020

Xuemei Du

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32782280%20AND%20SRC:MED&resulttype=core&format=json

14 August 2020

Guangzhong Xu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32782280%20AND%20SRC:MED&resulttype=core&format=json

14 August 2020

Xiyun Yan

1 reference

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14 August 2020

publication date

11 August 2020

1 reference

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Signal Transduction and Targeted Therapy

14 August 2020

published in

1 reference

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14 August 2020

volume

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14 August 2020

issue

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14 August 2020

page(s)

148

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MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily

14 August 2020

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Activation of Human Endothelial Cells via S-Endo-1 Antigen (CD146) Stimulates the Tyrosine Phosphorylation of Focal Adhesion Kinase p125FAK

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hShroom1 links a membrane bound protein to the actin cytoskeleton.

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Therapeutic targeting of soluble CD146/MCAM with the M2J-1 monoclonal antibody prevents metastasis development and procoagulant activity in CD146-positive invasive tumors

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7 January 2021

Visualization of CD146 dimerization and its regulation in living cells

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7 January 2021

CD146, a multi-functional molecule beyond adhesion

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7 January 2021

Ligand reduces galectin-1 sensitivity to oxidative inactivation by enhancing dimer formation

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7 January 2021

HEMCAM, an adhesion molecule expressed by c-kit+ hemopoietic progenitors

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7 January 2021

Comparative studies of the proteome, glycoproteome, and N-glycome of clear cell renal cell carcinoma plasma before and after curative nephrectomy

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7 January 2021

Cell surface glycoproteomic analysis of prostate cancer-derived PC-3 cells

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ß-1,3-galactosyl-O-glycosyl-glycoprotein ß-1,6-N-acetylglucosaminyltransferase 3 Increases MCAM Stability, Which Enhances S100A8/A9-Mediated Cancer Motility.

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7 January 2021

CD146 mediates VEGF-induced melanoma cell extravasation through FAK activation

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7 January 2021

A novel anti-CD146 antibody specifically targets cancer cells by internalizing the molecule

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7 January 2021

Direct correlation between MUC18 expression and metastatic potential of human melanoma cells.

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7 January 2021

CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer

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7 January 2021

Increased expression of CD146 and microvessel density (MVD) in invasive micropapillary carcinoma of the breast: Comparative study with invasive ductal carcinoma-not otherwise specified

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7 January 2021

Frequent and increased expression of human METCAM/MUC18 in cancer tissues and metastatic lesions is associated with the clinical progression of human ovarian carcinoma

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7 January 2021

Targeting CD146 in combination with vorinostat for the treatment of ovarian cancer cells

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7 January 2021

Expression of the cell adhesion molecule CD146/MCAM in non-small cell lung cancer.

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7 January 2021

MCAM expression is associated with poor prognosis in non-small cell lung cancer

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7 January 2021

CD146 protein in prostate cancer: revisited with two different antibodies

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7 January 2021

Hypermethylation of MCAM gene is associated with advanced tumor stage in prostate cancer.

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7 January 2021

Enforced Expression of METCAM/MUC18 Increases Tumorigenesis of Human Prostate Cancer LNCaP Cells in Nude Mice

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7 January 2021

Targeting CD146 with a 64Cu-labeled antibody enables in vivo immunoPET imaging of high-grade gliomas.

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7 January 2021

CD146 gene expression in clear cell renal cell carcinoma: a potential marker for prediction of early recurrence after nephrectomy

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7 January 2021

CD146 promotes metastasis and predicts poor prognosis of hepatocellular carcinoma

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7 January 2021

CD146-targeted immunoPET and NIRF Imaging of Hepatocellular Carcinoma with a Dual-Labeled Monoclonal Antibody

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7 January 2021

CD146 expression correlates with epithelial-mesenchymal transition markers and a poor prognosis in gastric cancer

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Melanoma progression-associated glycoprotein MUC18/MCAM mediates homotypic cell adhesion through interaction with a heterophilic ligand

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7 January 2021

Dual role of melanoma cell adhesion molecule (MCAM)/CD146 in lymphocyte endothelium interaction: MCAM/CD146 promotes rolling via microvilli induction in lymphocyte and is an endothelial adhesion receptor

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7 January 2021

A subset of host B lymphocytes controls melanoma metastasis through a melanoma cell adhesion molecule/MUC18-dependent interaction: evidence from mice and humans

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7 January 2021

Purification and characterization of an 82-kD membrane protein as a neurite outgrowth factor binding protein: possible involvement of NOF binding protein in axonal outgrowth in developing retina

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7 January 2021

Molecular cloning and functional expression of gicerin, a novel cell adhesion molecule that binds to neurite outgrowth factor.

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7 January 2021

Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS

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7 January 2021

Laminins 411 and 421 differentially promote tumor cell migration via α6β1 integrin and MCAM (CD146).

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7 January 2021

CD146 is a coreceptor for VEGFR-2 in tumor angiogenesis.

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7 January 2021

CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development.

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7 January 2021

CD146: a potential therapeutic target for systemic sclerosis.

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7 January 2021

CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development

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7 January 2021

Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis

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7 January 2021

A simplified laminin nomenclature

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7 January 2021

Laminin functions in tissue morphogenesis.

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7 January 2021

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7 January 2021

Cardiomyopathy associated with microcirculation dysfunction in laminin alpha4 chain-deficient mice.

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7 January 2021

Deletion of the laminin alpha4 chain leads to impaired microvessel maturation

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7 January 2021

Impeded interaction between Schwann cells and axons in the absence of laminin alpha4.

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7 January 2021

Rac regulates integrin-mediated endothelial cell adhesion and migration on laminin-8.

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7 January 2021

Purification and characterization of human laminin-8. Laminin-8 stimulates cell adhesion and migration through alpha3beta1 and alpha6beta1 integrins

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7 January 2021

Alpha4 chain laminins are widely expressed in renal cell carcinomas and have a de-adhesive function

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7 January 2021

Laminin isoforms and their integrin receptors in glioma cell migration and invasiveness: Evidence for a role of alpha5-laminin(s) and alpha3beta1 integrin

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7 January 2021

Epithelial-mesenchymal transition downregulates laminin alpha5 chain and upregulates laminin alpha4 chain in oral squamous carcinoma cells

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7 January 2021

Melanoma cells produce multiple laminin isoforms and strongly migrate on α5 laminin(s) via several integrin receptors.

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7 January 2021

Localization of laminin alpha4-chain in developing and adult human tissues

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7 January 2021

Monocytic Cells Synthesize, Adhere to, and Migrate on Laminin-8 ( 4 1 1)

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7 January 2021

Identification of an active site on the laminin alpha4 chain globular domain that binds to alphavbeta3 integrin and promotes angiogenesis

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7 January 2021

Overexpression of laminin-8 in human dermal microvascular endothelial cells promotes angiogenesis-related functions

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7 January 2021

Blood platelets contain and secrete laminin-8 (alpha4beta1gamma1) and adhere to laminin-8 via alpha6beta1 integrin

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7 January 2021

Chondroitin sulphate modification in the alpha4 chain of human recombinant laminin-8 (alpha4beta1gamma1).

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7 January 2021

Recombinant laminin-8 (alpha(4)beta(1)gamma(1)). Production, purification,and interactions with integrins.

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7 January 2021

Expression of IL-17 mRNA in ovarian cancer

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7 January 2021

Endogenous IL-17 contributes to reduced tumor growth and metastasis

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7 January 2021

Pericytic-like angiotropism of glioma and melanoma cells

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7 January 2021

Laminin-8/9 is synthesized by rat glomerular mesangial cells and is required for PDGF-induced mesangial cell migration

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7 January 2021

Rat glomerular mesangial cells require laminin-9 to migrate in response to insulin-like growth factor binding protein-5.

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7 January 2021

Laminin-421 produced by lymphatic endothelial cells induces chemotaxis for human melanoma cells

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7 January 2021

Monoclonal antibodies to human laminin α4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of α6β1 integrin and MCAM to α4-laminins

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7 January 2021

Vascular galectins: regulators of tumor progression and targets for cancer therapy.

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7 January 2021

Role of Galectins in Tumors and in Clinical Immunotherapy

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7 January 2021

Galectins: a family of animal beta-galactoside-binding lectins

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7 January 2021

Identification of galectin-1 as a novel mediator for chemoresistance in chronic myeloid leukemia cells

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7 January 2021

Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege

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7 January 2021

Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration

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7 January 2021

Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008.

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7 January 2021

Galectin-1 promotes hepatocellular carcinoma and the combined therapeutic effect of OTX008 galectin-1 inhibitor and sorafenib in tumor cells

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7 January 2021

Randomised clinical study: GR-MD-02, a galectin-3 inhibitor, vs. placebo in patients having non-alcoholic steatohepatitis with advanced fibrosis

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7 January 2021

Predictive Biomarkers for Checkpoint Inhibitor-Based Immunotherapy: The Galectin-3 Signature in NSCLCs

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7 January 2021

Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens

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7 January 2021

Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors

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7 January 2021

Galectin-1, a novel ligand of neuropilin-1, activates VEGFR-2 signaling and modulates the migration of vascular endothelial cells

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7 January 2021

Inhibiton of RET and JAK2 signals and upregulation of VEGFR3 phosphorylation in vitro by galectin-1 in trophoblast tumor cells BeWo

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7 January 2021

A unique galectin signature in human prostate cancer progression suggests galectin-1 as a key target for treatment of advanced disease.

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7 January 2021

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma

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7 January 2021

Decellularized matrix from tumorigenic human mesenchymal stem cells promotes neovascularization with galectin-1 dependent endothelial interaction

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7 January 2021

The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells.

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7 January 2021

Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential

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7 January 2021

Galectin-1: a small protein with major functions

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7 January 2021

Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer

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7 January 2021

Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target

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7 January 2021

On the role of galectin-3 in cancer apoptosis

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7 January 2021

Galectin-3 expression correlates with apoptosis of tumor-associated lymphocytes in human melanoma biopsies

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7 January 2021

Galectins as modulators of tumour progression

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7 January 2021

Galectin-3--a jack-of-all-trades in cancer

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7 January 2021

Circulating galectin-3 promotes metastasis by modifying MUC1 localization on cancer cell surface

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7 January 2021

Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion.

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7 January 2021

Interaction of the Oncofetal Thomsen-Friedenreich Antigen with Galectins in Cancer Progression and Metastasis

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7 January 2021

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

1 reference

7 January 2021

Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

CD146 interacts with galectin-3 to mediate endothelial cell migration.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

NMR-based insight into galectin-3 binding to endothelial cell adhesion molecule CD146: Evidence for noncanonical interactions with the lectin's CRD β-sandwich F-face

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Isolation of a tumor factor responsible for angiogenesis

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7 January 2021

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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7 January 2021

Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy

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https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Galectin-3 induces endothelial cell morphogenesis and angiogenesis

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https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Galectin-3 in angiogenesis and metastasis.

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https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Galectin-3 accelerates M2 macrophage infiltration and angiogenesis in tumors

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https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Evolution of the S100 family of calcium sensor proteins

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https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

A soluble protein characteristic of the nervous system

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7 January 2021

Functions of S100 proteins.

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https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature)

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Mast cell and monocyte recruitment by S100A12 and its hinge domain

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Inflammation and cancer: back to Virchow?

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Leukocytes, inflammation, and angiogenesis in cancer: fatal attractions

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Structural Basis for Ligand Recognition and Activation of RAGE

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The 1.5 Å Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE) Ectodomains Reveals Unique Features Determining Ligand Binding

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Structural insights into calcium-bound S100P and the V domain of the RAGE complex

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Hexameric calgranulin C (S100A12) binds to the receptor for advanced glycated end products (RAGE) using symmetric hydrophobic target-binding patches

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

S100B protein regulates myoblast proliferation and differentiation by activating FGFR1 in a bFGF-dependent manner.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

CD166/ALCAM mediates proinflammatory effects of S100B in delayed type hypersensitivity

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

CD68 on rat macrophages binds tightly to S100A8 and S100A9 and helps to regulate the cells' immune functions

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The S100A4 Protein Signals through the ErbB4 Receptor to Promote Neuronal Survival

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The Ca2+-binding proteins S100A8 and S100A9 are encoded by novel injury-regulated genes

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

A partial catalog of proteins secreted by epidermal keratinocytes in culture

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

S100A8 and S100A9 in inflammation and cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

A review of the S100 proteins in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Novel insights into the role of S100A8/A9 in skin biology

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

A CXCL1 paracrine network links cancer chemoresistance and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

S100A8/A9 Activate Key Genes and Pathways in Colon Tumor Progression

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

S100B protein detection in serum is a significant prognostic factor in metastatic melanoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

S100A9 induces differentiation of acute myeloid leukemia cells through TLR4.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Elevated S100A8 protein expression in breast cancer cells and breast tumor stroma is prognostic of poor disease outcome

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

High density of S100A9 positive inflammatory cells in prostate cancer stroma is associated with poor outcome

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

S100A8 and S100A9 overexpression is associated with poor pathological parameters in invasive ductal carcinoma of the breast

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The S100 family heterodimer, MRP-8/14, binds with high affinity to heparin and heparan sulfate glycosaminoglycans on endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Two proteins modulating transendothelial migration of leukocytes recognize novel carboxylated glycans on endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

exSSSRs (extracellular S100 Soil Sensor Receptors)-Fc fusion proteins work as prominent decoys to S100A8/A9-induced lung tropic cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The distribution of secondary growths in cancer of the breast. 1889

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Quantitative proteomics reveals ER-α involvement in CD146-induced epithelial-mesenchymal transition in breast cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Semaphorin 3A upregulates FOXO 3a-dependent MelCAM expression leading to attenuation of breast tumor growth and angiogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

A novel signaling axis of matriptase/PDGF-D/ß-PDGFR in human prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Matriptase: a culprit in cancer?

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: implications for breast cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Membrane-anchored serine proteases in vertebrate cell and developmental biology

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Neural transmembrane protease and endothelial Gs protein activation in cell contact-dependent signaling between neural stem/progenitor cells and brain endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

VEGF and Intraocular Neovascularization: From Discovery to Therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Pericytes of the neurovascular unit: key functions and signaling pathways.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Pericytes: developmental, physiological, and pathological perspectives, problems, and promises

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

CD146 is essential for PDGFRβ-induced pericyte recruitment

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

VEGF-A: a critical regulator of blood vessel growth

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Vascular endothelial growth factor and angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Signal transduction by vascular endothelial growth factor receptors

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Acidification of three types of liver endocytic vesicles: similarities and differences

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Expression of vascular endothelial growth factor receptors 1, 2, and 3 in quiescent endothelia

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Expression of vascular endothelial growth factor receptors in smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Adhesion proteins meet receptors: a common theme?

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Knockdown of CD146 reduces the migration and proliferation of human endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Identification of the S-Endo 1 endothelial-associated antigen

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Identification of CD146 as a component of the endothelial junction involved in the control of cell-cell cohesion.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Reciprocal regulation of MelCAM and AKT in human melanoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Anti-CD146 monoclonal antibody AA98 inhibits angiogenesis via suppression of nuclear factor-kappaB activation.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303).

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Evading tumor evasion: current concepts and perspectives of anti-angiogenic cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF-induced neutrophil recruitment

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Mechanism of action and in vivo role of platelet-derived growth factor

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Targeting the PDGF signaling pathway in tumor treatment

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Expression and purification of functional PDGF receptor beta.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

LHT7, a chemically modified heparin, inhibits multiple stages of angiogenesis by blocking VEGF, FGF2 and PDGF-B signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Platelet-derived growth factor B retention is essential for development of normal structure and function of conduit vessels and capillaries

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The MAPK signaling cascade

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Inositol trisphosphate and calcium signalling mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The PDGF B-chain is involved in the ontogenic susceptibility of the developing rat brain to NMDA toxicity

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Genes tell lymphatics to sprout or not

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Vascular growth factors and lymphangiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Chy-3 mice are Vegfc haploinsufficient and exhibit defective dermal superficial to deep lymphatic transition and dermal lymphatic hypoplasia

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Transgenic induction of vascular endothelial growth factor-C is strongly angiogenic in mouse embryos but leads to persistent lymphatic hyperplasia in adult tissues

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Pulmonary lymphangiectasia resulting from vascular endothelial growth factor-C overexpression during a critical period

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Proteolytic processing regulates receptor specificity and activity of VEGF-C

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Pressing the right buttons: signaling in lymphangiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Novel zebrafish model reveals a critical role for MAPK in lymphangiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Direct recruitment of CRK and GRB2 to VEGFR-3 induces proliferation, migration, and survival of endothelial cells through the activation of ERK, AKT, and JNK pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Modulation of VEGFR-2-mediated endothelial-cell activity by VEGF-C/VEGFR-3.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Matrix metalloproteinase 14 participates in corneal lymphangiogenesis through the VEGF-C/VEGFR-3 signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Further evidence for expression and function of the VEGF-C/VEGFR-3 axis in cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The role of the VEGF-C/VEGFR-3 axis in cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Lymphangiogenesis in development and human disease

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Lymphangiogenesis and lymphatic vessel remodelling in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

C/EBP-δ regulates VEGF-C autocrine signaling in lymphangiogenesis and metastasis of lung cancer through HIF-1α.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Inhibition of lymphogenous metastasis using adeno-associated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Suppression of VEGFR-3 signaling inhibits lymph node metastasis in gastric cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Inhibition of VEGFR-3 activation with the antagonistic antibody more potently suppresses lymph node and distant metastases than inactivation of VEGFR-2.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Down-regulation of vascular endothelial cell growth factor-C expression using small interfering RNA vectors in mammary tumors inhibits tumor lymphangiogenesis and spontaneous metastasis and enhances survival

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Alternative Wnt pathways and receptors

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

When pathways collide: collaboration and connivance among signalling proteins in development.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The WNT signaling pathway from ligand secretion to gene transcription: molecular mechanisms and pharmacological targets

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

PI3K/Akt-dependent phosphorylation of GSK3β and activation of RhoA regulate Wnt5a-induced gastric cancer cell migration

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

C-Jun N-terminal kinase (JNK) mediates Wnt5a-induced cell motility dependent or independent of RhoA pathway in human dental papilla cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Activation of cellular gene by mouse mammary tumour virus may occur early in mammary tumour development

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Wnt signaling in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Netrin-1: when a neuronal guidance cue turns out to be a regulator of tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The dependence receptors DCC and UNC5H as a link between neuronal guidance and survival

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The netrin protein family

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Identification and expression of mouse netrin-4.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Proteoglycans as modulators of axon guidance cue function.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

The Netrin family of guidance factors: emphasis on Netrin-1 signalling

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Netrin-1 inhibits leukocyte migration in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Netrin-1 and its dependence receptors as original targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Plasma netrin-1 is a diagnostic biomarker of human cancers

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Netrin-1 as a novel therapeutic target in cardiovascular disease: to activate or inhibit?

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Netrin-1: a novel universal biomarker of human kidney injury

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Membrane proteins with immunoglobulin-like domains--a master superfamily of interaction molecules

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Netrins and their receptors

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Physiological functions and underlying mechanisms of fibroblast growth factor (FGF) family members: recent findings and implications for their pharmacological application

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Fibroblast growth factors

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

FGF-Regulated ETV Transcription Factors Control FGF-SHH Feedback Loop in Lung Branching

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Metabolic roles of endocrine fibroblast growth factors.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Cell movement patterns during gastrulation in the chick are controlled by positive and negative chemotaxis mediated by FGF4 and FGF8.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Exploring mechanisms of FGF signalling through the lens of structural biology

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

FOXO transcription factors throughout T cell biology

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Role of heparan sulfate as a tissue-specific regulator of FGF-4 and FGF receptor recognition

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Recognition of CD146 as an ERM-binding protein offers novel mechanisms for melanoma cell migration.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

Endothelial CD146 is required for in vitro tumor-induced angiogenesis: the role of a disulfide bond in signaling and dimerization

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

NADPH oxidase 4 mediates reactive oxygen species induction of CD146 dimerization in VEGF signal transduction.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-020-00259-8

7 January 2021

10.1038/S41392-020-00259-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32782280%20AND%20SRC:MED&resulttype=core&format=json

14 August 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32782280%20AND%20SRC:MED&resulttype=core&format=json