Genetics of HCC: Novel approaches to explore molecular diversity (Q95942040)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

title

Genetics of HCC: Novel approaches to explore molecular diversity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

main subject

hepatocellular carcinoma

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Stefano Caruso

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Daniel R O'Brien

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Sean P Cleary

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Lewis R Roberts

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

publication date

28 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

cites work

Hepatocellular Carcinoma

1 reference

7 January 2021

Toward understanding and exploiting tumor heterogeneity

1 reference

7 January 2021

Germline and somatic DICER1 mutations in familial and sporadic liver tumors.

1 reference

7 January 2021

Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.

1 reference

7 January 2021

Single nucleotide polymorphisms and risk of hepatocellular carcinoma in cirrhosis

1 reference

7 January 2021

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

1 reference

7 January 2021

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

1 reference

7 January 2021

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

1 reference

7 January 2021

PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases

1 reference

7 January 2021

A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.

1 reference

7 January 2021

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

1 reference

7 January 2021

Genomic portrait of resectable hepatocellular carcinomas: implications of RB1 and FGF19 aberrations for patient stratification

1 reference

7 January 2021

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

1 reference

7 January 2021

Clinical Impact of Genomic Diversity From Early to Advanced Hepatocellular Carcinoma

1 reference

7 January 2021

The role of telomeres and telomerase in cirrhosis and liver cancer

1 reference

7 January 2021

Analysis of Liver Cancer Cell Lines Identifies Agents With Likely Efficacy Against Hepatocellular Carcinoma and Markers of Response

1 reference

7 January 2021

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

1 reference

7 January 2021

Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stress

1 reference

7 January 2021

The role of hepatitis B virus integrations in the pathogenesis of human hepatocellular carcinoma

1 reference

7 January 2021

Microhomology-mediated mechanisms underlie non-recurrent disease-causing microdeletions of the FOXL2 gene or its regulatory domain

1 reference

7 January 2021

Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers.

1 reference

7 January 2021

The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients.

1 reference

7 January 2021

Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach

1 reference

7 January 2021

Viral-human chimeric transcript predisposes risk to liver cancer development and progression.

1 reference

7 January 2021

High Rate of Detection of Human ESPL1-HBV S Fusion Gene in Patients With HBV-related Liver Cancer: A Chinese Case-Control Study

1 reference

7 January 2021

Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma.

1 reference

7 January 2021

Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas

1 reference

7 January 2021

Adeno-associated virus in the liver: natural history and consequences in tumour development

1 reference

7 January 2021

Intratumor heterogeneity in hepatocellular carcinoma

1 reference

7 January 2021

Polyploidy spectrum: a new marker in HCC classification

1 reference

7 January 2021

The clonal evolution of tumor cell populations

1 reference

7 January 2021

Genomic Medicine and Implications for Hepatocellular Carcinoma Prevention and Therapy

1 reference

7 January 2021

The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma

1 reference

7 January 2021

Genomic and Epigenomic Heterogeneity of Hepatocellular Carcinoma.

1 reference

7 January 2021

A Big Bang model of human colorectal tumor growth

1 reference

7 January 2021

Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution

1 reference

7 January 2021

Intra-tumor heterogeneity from a cancer stem cell perspective.

1 reference

7 January 2021

Single cell analysis reveals cancer stem cell heterogeneity in hepatocellular carcinoma.

1 reference

7 January 2021

Genomic and Epigenomic Features of Primary and Recurrent Hepatocellular Carcinomas

1 reference

7 January 2021

Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer

1 reference

7 January 2021

Whole genome sequencing discriminates hepatocellular carcinoma with intrahepatic metastasis from multi-centric tumors

1 reference

7 January 2021

Identifying Clonal Origin of Multifocal Hepatocellular Carcinoma and Its Clinical Implications

1 reference

7 January 2021

Genomic and transcriptional heterogeneity of multifocal hepatocellular carcinoma

1 reference

7 January 2021

Integrated multiomic analysis reveals comprehensive tumour heterogeneity and novel immunophenotypic classification in hepatocellular carcinomas

1 reference

7 January 2021

Variable Intra-Tumor Genomic Heterogeneity of Multiple Lesions in Patients With Hepatocellular Carcinoma

1 reference

7 January 2021

Tumour heterogeneity and resistance to cancer therapies

1 reference

7 January 2021

Intratumoral heterogeneity and clonal evolution in liver cancer

1 reference

7 January 2021

Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets

1 reference

7 January 2021

Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma

1 reference

7 January 2021

Molecular and histological correlations in liver cancer

1 reference

7 January 2021

Gene signatures in the management of hepatocellular carcinoma

1 reference

7 January 2021

A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells

1 reference

7 January 2021

Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma

1 reference

7 January 2021

A Hepatocellular Carcinoma 5-Gene Score Associated With Survival of Patients After Liver Resection

1 reference

7 January 2021

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

1 reference

7 January 2021

An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.

1 reference

7 January 2021

A landscape of pharmacogenomic interactions in cancer.

1 reference

7 January 2021

Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens

1 reference

7 January 2021

Molecular subtype and response to dasatinib, an Src/Abl small molecule kinase inhibitor, in hepatocellular carcinoma cell lines in vitro

1 reference

7 January 2021

In vitro modeling of hepatocellular carcinoma molecular subtypes for anti-cancer drug assessment

1 reference

7 January 2021

A Pharmacogenomic Landscape in Human Liver Cancers

1 reference

7 January 2021

Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents.

1 reference

7 January 2021

Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers.

1 reference

7 January 2021

Mouse models of hepatocellular carcinoma: an overview and highlights for immunotherapy research

1 reference

7 January 2021

Integrative genomic analysis of mouse and human hepatocellular carcinoma

1 reference

7 January 2021

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.

1 reference

7 January 2021

Establishment of a hepatocellular carcinoma patient-derived xenograft platform and its application in biomarker identification

1 reference

7 January 2021

Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy.

1 reference

7 January 2021

Liver organoids: from basic research to therapeutic applications

1 reference

7 January 2021

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

1 reference

7 January 2021

Long-term culture of genome-stable bipotent stem cells from adult human liver

1 reference

7 January 2021

Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

1 reference

7 January 2021

Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture

1 reference

7 January 2021

Vascularized and functional human liver from an iPSC-derived organ bud transplant

1 reference

7 January 2021

Human primary liver cancer-derived organoid cultures for disease modeling and drug screening

1 reference

7 January 2021

Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies

1 reference

7 January 2021

Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity

1 reference

7 January 2021

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

1 reference

7 January 2021

Identifiers

DOI

10.1002/HEP.31394

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32463918%20AND%20SRC:MED&resulttype=core&format=json