Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia (Q83967551)

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scientific article published on 26 April 2011

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English	Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia	scientific article published on 26 April 2011

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scholarly article

1 reference

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Europe PubMed Central

PubMed publication ID

21519855

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

title

Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

main subject

acute myeloid leukemia

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author

María-Belén Vidriales

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Stéphane de Botton

series ordinal

4

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Charles Dumontet

series ordinal

7

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Jesús San Miguel

series ordinal

12

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

author name string

Simona Lapusan

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Xavier Thomas

series ordinal

3

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Anne Vekhoff

series ordinal

5

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Ruoping Tang

series ordinal

6

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stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Rodica Morariu-Zamfir

series ordinal

8

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

John M Lambert

series ordinal

9

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Marie-Laure Ozoux

series ordinal

10

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Philippe Poncelet

series ordinal

11

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Ollivier Legrand

series ordinal

13

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Daniel J DeAngelo

series ordinal

14

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Francis J Giles

series ordinal

15

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Jean-Pierre Marie

series ordinal

16

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

publication date

26 April 2011

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stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

published in

Investigational New Drugs

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Europe PubMed Central

PubMed publication ID

21519855

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

volume

30

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stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

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29 January 2020

issue

3

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

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29 January 2020

page(s)

1121-1131

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Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

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29 January 2020

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Recombinant immunotoxins for the treatment of chemoresistant hematologic malignancies.

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PubMed

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Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay.

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PubMed

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Acute leukemia in adolescents and young adults

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21519855

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P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21519855

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Antimitotic Activity of the Potent Tumor Inhibitor Maytansine

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Maytansine, a novel antileukemic ansa macrolide from Maytenus ovatus

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Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate

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The immunophenotype of 177 adults with acute myeloid leukemia: proposal of a prognostic score

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Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing.

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PubMed

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Maytansine

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21519855

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Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

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https://pubmed.ncbi.nlm.nih.gov/21519855

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Acute myeloid leukemia in the elderly

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21519855

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12 December 2020

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Acute myelogenous leukemia

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21519855

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Binding of maytansine to tubulin: competition with other mitotic inhibitors

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21519855

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12 December 2020

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Identifiers

DOI

10.1007/S10637-011-9670-0

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

Dimensions Publication ID

1043629304

0 references

PubMed publication ID

21519855

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21519855

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21519855%20AND%20SRC:MED&resulttype=core&format=json

retrieved

29 January 2020

 

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