Interleukin-12 is necessary for the priming of CD4+ T cells required during the elicitation of HIV-1 gp120-specific cytotoxic T-lymphocyte function (Q80769010)

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scientific article published on 20 February 2008

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English	Interleukin-12 is necessary for the priming of CD4+ T cells required during the elicitation of HIV-1 gp120-specific cytotoxic T-lymphocyte function	scientific article published on 20 February 2008

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18298551%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Interleukin-12 is necessary for the priming of CD4+ T cells required during the elicitation of HIV-1 gp120-specific cytotoxic T-lymphocyte function (English)

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3 January 2020

author name string

Shalini Gupta

1

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3 January 2020

Ramanamurthy Boppana

2

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3 January 2020

Gyan C Mishra

3

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3 January 2020

Bhaskar Saha

4

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3 January 2020

Debashis Mitra

5

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3 January 2020

publication date

20 February 2008

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3 January 2020

number of pages

9

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inferred from page(s)

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3 January 2020

124

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3 January 2020

4

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3 January 2020

553-561

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PubMed publication ID

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3 January 2020

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

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Cytokines and cytokine therapies in HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

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Therapeutic immunization of HIV-infected chimpanzees using HIV-1 plasmid antigens and interleukin-12 expressing plasmids.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of anti-human immunodeficiency virus type 1 (HIV-1) responses in CD8+ T cells from late-stage patients on prolonged antiretroviral therapy by stimulation in vitro with HIV-1 protein-loaded dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of T cell help for anti-viral CTL responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and purification of glutathione S-transferase-tagged HIV-1 gp120: no evidence of an interaction with CD26.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent numbers of tetramer+ CD8(+) T cells, but loss of interferon-gamma+ HIV-specific T cells during progression to AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

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A Phase I, placebo-controlled trial of multi-dose recombinant human interleukin-12 in patients with HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional significance of the perforin/granzyme cell death pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased stimulation of CD4+ T cell proliferation and IL-2 production by highly enriched populations of HIV-infected dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 and dendritic cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased immune activation precedes the inflection point of CD4 T cells and the increased serum virus load in human immunodeficiency virus infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of interferon gamma induced interleukin 12 production: a potential mechanism for the anti-inflammatory activities of tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

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Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein levels of interleukin-12 p70 holomer, its p40 chain and interferon-gamma during advancing HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 is not required for induction of type 1 cytokine responses in viral infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-13 and IFN-gamma secretion by activated T cells in HIV-1 infection associated with viral suppression and a lack of disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interleukin-12-mediated pathway of immune events is dysfunctional in human immunodeficiency virus-infected individuals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased CD40 ligand induction in CD4 T cells and dysregulated IL-12 production during HIV infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The B7 family revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperation between CD4+ and CD8+ T cells: when, where, and how.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and E.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Granzyme B: pro-apoptotic, antiviral and antitumor functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 engagement enhances antigen-presenting langerhans cell priming of IFN-gamma-producing CD4+ and CD8+ T cells independently of IL-12.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noninfectious cofactors in susceptibility to AIDS: possible contributions of semen, HLA alloantigens, and lack of natural resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of HIV-1 gp120 and human soluble CD4 by recombinant baculoviruses and their interaction in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The JAM test. A simple assay for DNA fragmentation and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired interleukin 12 production in human immunodeficiency virus-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40/CD40 ligand interactions are required for T cell-dependent production of interleukin-12 by mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular analysis of decreased interleukin-12 production in persons infected with human immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type 1 and type 2 cytokine profiles in children exposed to or infected with vertically transmitted human immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-12 production by dendritic cells. The role of CD40-CD40L interactions in Th1 T-cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with mycobacterium tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of the Th1 to Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase 1 trial of a single dose of recombinant human interleukin-12 in human immunodeficiency virus-infected patients with 100-500 CD4 cells/microL.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18298551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2567.2008.02809.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18298551%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18298551%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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