Discovery of Small-Molecule Activators for Glucose-6-Phosphate Dehydrogenase (G6PD) Using Machine Learning Approaches (Q89895478)

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scientific article published on 23 February 2020

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English	Discovery of Small-Molecule Activators for Glucose-6-Phosphate Dehydrogenase (G6PD) Using Machine Learning Approaches	scientific article published on 23 February 2020

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scholarly article

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Europe PubMed Central

PMC publication ID

7073180

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 April 2020

title

Discovery of Small-Molecule Activators for Glucose-6-Phosphate Dehydrogenase (G6PD) Using Machine Learning Approaches (English)

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stated in

Europe PubMed Central

PMC publication ID

7073180

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

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9 April 2020

main subject

machine learning

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author

Madhu Sudhana Saddala

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1

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Europe PubMed Central

PMC publication ID

7073180

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

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9 April 2020

Anton Lennikov

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2

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Europe PubMed Central

PMC publication ID

7073180

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

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9 April 2020

author name string

Hu Huang

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3

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Europe PubMed Central

PMC publication ID

7073180

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

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9 April 2020

publication date

23 February 2020

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Europe PubMed Central

PMC publication ID

7073180

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

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9 April 2020

published in

International Journal of Molecular Sciences

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stated in

Europe PubMed Central

PMC publication ID

7073180

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 April 2020

volume

21

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Europe PubMed Central

PMC publication ID

7073180

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

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9 April 2020

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4

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Europe PubMed Central

PMC publication ID

7073180

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

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9 April 2020

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Creative Commons Attribution 4.0 International

start time

23 February 2020

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machine learning

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cites work

Glucose 6-phosphate dehydrogenase mutations causing enzyme deficiency in a model of the tertiary structure of the human enzyme.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired production of nitric oxide, superoxide, and hydrogen peroxide in glucose 6-phosphate-dehydrogenase-deficient granulocytes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human glucose-6-phosphate dehydrogenase: the crystal structure reveals a structural NADP(+) molecule and provides insights into enzyme deficiency

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Results of a new classification algorithm combining K nearest neighbors and recursive partitioning.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heuristics for similarity searching of chemical graphs using a maximum common edge subgraph algorithm

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis and display of the size dependence of chemical similarity coefficients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CASTp: Computed Atlas of Surface Topography of proteins

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct phenotypic expression of two de novo missense mutations affecting the dimer interface of glucose-6-phosphate dehydrogenase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feature selection for descriptor based classification models. 2. Human intestinal absorption (HIA).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systematic benchmarking of microarray data classification: assessing the role of non-linearity and dimensionality reduction

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Virtual Computational Chemistry Laboratory – Design and Description

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidants reduce cone cell death in a model of retinitis pigmentosa

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidants slow photoreceptor cell death in mouse models of retinitis pigmentosa

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-6-phosphate dehydrogenase deficiency

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecule-pharmacophore superpositioning and pattern matching in computational drug design

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ChemmineR: a compound mining framework for R.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Another look at statistical learning theory and regularization

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Virtual high throughput screening using combined random forest and flexible docking

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased prevalence of proliferative retinopathy in patients with type 1 diabetes who are deficient in glucose-6-phosphate dehydrogenase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmer: Efficient and Exact Pharmacophore Search

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APCluster: an R package for affinity propagation clustering

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-6-phosphate dehydrogenase deficiency and type 2 diabetes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DrugLogit: logistic discrimination between drugs and nondrugs including disease-specificity by assigning probabilities based on molecular properties.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose 6-phosphate dehydrogenase deficiency increases redox stress and moderately accelerates the development of heart failure

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-6-phosphate-dehydrogenase deficiency and its correlation with other risk factors in jaundiced newborns in Southern Brazil

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model of glucose-6-phosphate dehydrogenase deficiency in the zebrafish

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain glucose-6-phosphate dehydrogenase protects against endogenous oxidative DNA damage and neurodegeneration in aged mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bilateral cataracts associated with glucose-6-phosphate dehydrogenase deficiency

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug/nondrug classification using Support Vector Machines with various feature selection strategies.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MLViS: A Web Tool for Machine Learning-Based Virtual Screening in Early-Phase of Drug Discovery and Development

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-6-Phosphate Dehydrogenase Deficiency.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of Occult Acute Kidney Injury in Glucose-6-Phosphate Dehydrogenase Deficiency Anemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel 1, 4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular docking based screening of a simulated HIF-1 protein model for potential inhibitors.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of small molecules through pharmacophore modeling, docking and molecular dynamics simulation against Plasmodium vivax Vivapain-3 (VP-3).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Addressing the gender-knowledge gap in glucose-6-phosphate dehydrogenase deficiency: challenges and opportunities.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On quantification of geometry and topology of protein pockets and channels for assessing mutation effects

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular docking studies of angiogenesis target protein HIF-1α and genistein in breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small-Molecule Activators of Glucose-6-phosphate Dehydrogenase (G6PD) Bridging the Dimer Interface

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of novel inhibitors for TNFα, TNFR1 and TNFα-TNFR1 complex using pharmacophore-based approaches

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placental growth factor negatively regulates retinal endothelial cell barrier function through suppression of glucose-6-phosphate dehydrogenase and antioxidant defense systems

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/32102234

retrieved

12 December 2020

based on heuristic

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Identifiers

DOI

10.3390/IJMS21041523

1 reference

stated in

Europe PubMed Central

PMC publication ID

7073180

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 April 2020

PMC publication ID

7073180

1 reference

stated in

Europe PubMed Central

PMC publication ID

7073180

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 April 2020

PubMed publication ID

32102234

1 reference

stated in

Europe PubMed Central

PMC publication ID

7073180

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32102234%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 April 2020

 

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