TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics (Q88532415)

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25 March 2020

title

TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics (English)

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25 March 2020

Nigel J Cairns

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25 March 2020

Stephani A Davis

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25 March 2020

Sheed Itaman

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25 March 2020

Christopher M Khalid-Janney

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25 March 2020

Justin A Sherard

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25 March 2020

James A Dowell

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25 March 2020

Michael A Gitcho

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25 March 2020

publication date

30 April 2018

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25 March 2020

number of pages

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inferred from page(s)

published in

Neuroscience Letters

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25 March 2020

volume

678

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25 March 2020

page(s)

8-15

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Mitochondrial complex I deficiency in Parkinson's disease

25 March 2020

cites work

1 reference

12 December 2020

Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons.

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Ultrastructural study of synapses in the anterior horn neurons of patients with amyotrophic lateral sclerosis

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Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

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The role of the metabolic lesion in Alzheimer's disease.

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Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

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Enzymes of triacylglycerol synthesis and their regulation

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Structural diversity and functional implications of the eukaryotic TDP gene family

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Stress granule assembly is mediated by prion-like aggregation of TIA-1

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OPA1 requires mitofusin 1 to promote mitochondrial fusion

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Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions

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12 December 2020

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

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12 December 2020

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

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12 December 2020

TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

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12 December 2020

TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein

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12 December 2020

Mitochondrial clustering induced by overexpression of the mitochondrial fusion protein Mfn2 causes mitochondrial dysfunction and cell death

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12 December 2020

Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology.

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12 December 2020

Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death

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12 December 2020

Concurrence of TDP-43, tau and alpha-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies

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12 December 2020

Neuropathological aspects of Alzheimer disease, Parkinson disease and frontotemporal dementia

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12 December 2020

Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies

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12 December 2020

Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia

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12 December 2020

Isolation of mitochondria from rat brain using Percoll density gradient centrifugation

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Mutant huntingtin and mitochondrial dysfunction

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12 December 2020

Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies.

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12 December 2020

Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).

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12 December 2020

TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

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12 December 2020

Transactive response DNA-binding protein 43 burden in familial Alzheimer disease and Down syndrome

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12 December 2020

Nuclear factor TDP-43 can affect selected microRNA levels

1 reference

12 December 2020

Alterations in subcellular localization of TDP-43 immunoreactivity in the anterior horns in sporadic amyotrophic lateral sclerosis

1 reference

12 December 2020

Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

1 reference

12 December 2020

Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice.

1 reference

12 December 2020

β-amyloid triggers ALS-associated TDP-43 pathology in AD models

1 reference

12 December 2020

Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice

1 reference

12 December 2020

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

1 reference

12 December 2020

Mitochondrial dysfunction in human TDP-43 transfected NSC34 cell lines and the protective effect of dimethoxy curcumin

1 reference

12 December 2020

Full-length TDP-43 and its C-terminal fragments activate mitophagy in NSC34 cell line

1 reference

12 December 2020

Loss of prohibitin membrane scaffolds impairs mitochondrial architecture and leads to tau hyperphosphorylation and neurodegeneration

1 reference

12 December 2020

The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons

1 reference

12 December 2020

Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.

1 reference

12 December 2020

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease.

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12 December 2020

Activation of ER Stress and Autophagy Induced by TDP-43 A315T as Pathogenic Mechanism and the Corresponding Histological Changes in Skin as Potential Biomarker for ALS with the Mutation

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12 December 2020

Panorama of ancient metazoan macromolecular complexes

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12 December 2020

Mitophagy in APPsw/PS1dE9 transgenic mice and APPsw stably expressing in HEK293 cells

1 reference

12 December 2020

Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway.

1 reference

12 December 2020

The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity

1 reference

12 December 2020

The phosphatase calcineurin regulates pathological TDP-43 phosphorylation.

1 reference

12 December 2020

Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor.

1 reference

12 December 2020

Motor-Coordinative and Cognitive Dysfunction Caused by Mutant TDP-43 Could Be Reversed by Inhibiting Its Mitochondrial Localization

1 reference

12 December 2020

PHB2/prohibitin 2: An inner membrane mitophagy receptor

1 reference

12 December 2020

Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies.

1 reference

12 December 2020

TDP-43 expression influences amyloidβ plaque deposition and tau aggregation

1 reference

12 December 2020

Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo

1 reference

12 December 2020

Primary fibroblasts derived from sporadic amyotrophic lateral sclerosis patients do not show ALS cytological lesions

1 reference

12 December 2020

Cross-talk between pathogenic mechanisms in neurodegeneration: the role of oxidative stress in Amyotrophic Lateral Sclerosis

1 reference

12 December 2020

10.1016/J.NEULET.2018.04.053

Identifiers

DOI

1 reference

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25 March 2020

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25 March 2020

PubMed publication ID

29715546

1 reference

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