Pyrazolopyrimidine metabolism in parasitic protozoa (Q86846600)

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scientific article published on 01 September 1984

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English	Pyrazolopyrimidine metabolism in parasitic protozoa	scientific article published on 01 September 1984

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Europe PubMed Central

PubMed publication ID

24277328

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277328%20AND%20SRC:MED&resulttype=core&format=json

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1 March 2020

title

Pyrazolopyrimidine metabolism in parasitic protozoa (English)

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Europe PubMed Central

PubMed publication ID

24277328

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1 March 2020

author name string

B Ullman

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1

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Europe PubMed Central

PubMed publication ID

24277328

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1 March 2020

publication date

1 September 1984

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Europe PubMed Central

PubMed publication ID

24277328

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1 March 2020

published in

Pharmaceutical Research

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Europe PubMed Central

PubMed publication ID

24277328

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1 March 2020

volume

1

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Europe PubMed Central

PubMed publication ID

24277328

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1 March 2020

issue

5

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Europe PubMed Central

PubMed publication ID

24277328

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1 March 2020

page(s)

194-203

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Europe PubMed Central

PubMed publication ID

24277328

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277328%20AND%20SRC:MED&resulttype=core&format=json

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1 March 2020

cites work

Inherited disorder of purine metabolism. Correlation between central nervous system dysfunction and biochemical defects

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism and cytotoxic effects of formycin B in Trypanosoma cruzi

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animals as reservoir hosts of human trypanosomes

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation and anti-leishmanial activity of formycin B

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of the distribution and electron acceptor specificities of xanthine oxidase and aldehyde oxidase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of urate production by allopurinol

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of pyrazolo(3,4-d)pyrimidines in Leishmania braziliensis and Leishmania donovani. Allopurinol, oxipurinol, and 4-aminopyrazolo(3,4-d)pyrimidine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purine metabolism in Trypanosoma cruzi

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purine Metabolism in Trypanosomatids*

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic Analysis of Nucleoside Transport in Leishmania donovani

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trypanosoma rhodesiense: semiautomated microtesting for quantitation of antitrypanosomal activity in vitro

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of [6-14C]allopurinol—Lack of incorporation of allopurinol into nucleic acids

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PSEUDOFEEDBACK INHIBITION OF PURINE SYNTHESIS BY 6-MERCAPTOPURINE RIBONUCLEOTIDE AND OTHER PURINE ANALOGUES

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A specific enzyme defect in gout associated with overproduction of uric acid

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of allopurinol

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of adenylosuccinate synthetase and adenylosuccinate lyase from Leishmania donovani. Selective amination of an antiprotozoal agent

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purine and Pyrimidine Synthesis by the Avian Malaria Parasite, Plasmodium lophurae*

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allopurinol: Alteration in Pyrimidine Metabolism in Man

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal clearance of oxipurinol, the chief metabolite of allopurinol

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antileishmanial effect of allopurinol

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on formycin and formycin B in cells of Ehrlich carcinoma and E. coli

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antileishmanial effect of allopurinol. II. Relationship of adenine metabolism in Leishmania species to the action of allopurinol

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of nucleotides of (6-14C)allopurinol and (6-14C)oxipurinol in rat tissues and effects on uridine nucleotide pools

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and mechanism of action of formycin B in Leishmania

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the Mechanism of Inactivation of Xanthine Oxidase by Allopurinol and Other Pyrazolo[3,4-d]pyrimidines

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

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inferred from PubMed ID database lookup

Isotopes incorporated in the Nucleic Acids of Trypanosoma mega

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyrazolopyrimidine metabolism in African trypanosomes: metabolic similarities to Trypanosoma cruzi and Leishmania spp.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human hypoxanthine phosphoribosyltransferase. I. Purification, properties, and specificity.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of formycin B on polyadenosine diphosphoribose synthesis in vitro and in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purine nucleoside phosphorylase from human erythrocytes. 3. Inhibition by the inosine analog formycin B of the isolated enzyme and of nucleoside metabolism in intact erythrocytes and sarcoma 180 cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purine metabolism in Leishmania donovani and Leishmania braziliensis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleosidases from Leishmania donovani. Pyrimidine ribonucleosidase, purine ribonucleosidase, and a novel purine 2'-deoxyribonucleosidase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic studies of thiopurinol in man and the pig

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential metabolism of allopurinol and derivatives in Trypanosoma rangeli and T. cruzi culture forms

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purine-phosphoribosyltransferase activities in rat and mouse tissues and in Ehrlich ascites-tumour cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian adenylosuccinate synthetase. Nucleotide monophosphate substrates and inhibitors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allopurinol ribonucleoside as an antileishmanial agent. Biological effects, metabolism, and enzymatic phosphorylation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleoside hydrolases from Trypanosoma cruzi

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism of formycin B in Leishmania donovani

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trypanosoma cruzi: allopurinol in the treatment of mice with experimental acute Chagas disease

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

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Effect of allopurinol on Trypanosoma cruzi: metabolism and biological activity in intracellular and bloodstream forms

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

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inferred from PubMed ID database lookup

The Sites of Action of Allopurinol inCrithidia fasciculata*

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

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Depletion of erythrocyte phosphoribosylpyrophosphate in man.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic studies of allopurinol, an inhibitor of xanthine oxidase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antileishmanial action of 4-thiopyrazolo (3.4-d) pyrimidine and its ribonucleoside. Biological effects and metabolism

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

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RELATIONSHIP BETWEEN METABOLIC FATES AND ANTITUMOR ACTIVITIES OF THIOPURINES

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

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Effect of allopurinol on different strains of Trypanosoma cruzi

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

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Tissue distribution of purine ribosyl- and phosphoribosyltransferases in the Rhesus monkey

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

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Analysis of purine ribonucleotides and deoxyribonucleotides in cell extracts by high-performance liquid chromatography

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

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Pyrazolopyrimidine metabolism in the pathogenic trypanosomatidae

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

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Thiopurinol: dose-related effect on urinary oxypurine excretion

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formycin B resistance in Leishmania

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of allopurinol-mediated inhibition of pyrimidine biosynthesis

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

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A re-examination of purine and pyrimidine synthesis in the three main forms of Trypanosoma cruzi

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of the specificities of xanthine oxidase and aldehyde oxidase.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitrypanosomal Effect of Allopurinol: Conversion in Vivo to Aminopyrazolopyrimidine Nucleotides by Trypanosoma cruzi

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ribonucleosides of allopurinol and oxoallopurinol. Isolation from human urine, enzymatic synthesis, and characterization

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of allopurinol and oxipurinol on purine synthesis in cultured human cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

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Stoichiometric Inhibition of Reduced Xanthine Oxidase by Hydroxypyrazolo[3,4-d]pyrimidines

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

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Antileishmanial effect of allopurinol and allopurinol ribonucleoside on intracellular forms of Leishmania donovani

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

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Reaction mechanism and specificity of human GMP reductase. Substrates, inhibitors, activators, and inactivators

1 reference

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

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Guanosine 5'-monophosphate reductase from Leishmania donovani. A possible chemotherapeutic target

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

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Adenine aminohydrolase: occurrence and possible significance in trypanosomid flagellates

1 reference

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

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Antagonists of Growth Inhibition ofCrithidiaby Allopurinol, a Guanine Analog

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical genetic analysis of formycin B action in Leishmania donovani

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenylosuccinate synthetase and adenylosuccinate lyase from Trypanosoma cruzi, Specificity studies with potential chemotherapeutic agents

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

based on heuristic

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The Morphology and Life Cycles of Trypanosomes

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

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A minimal medium for the growth ofPlasmodium knowlesiin dilution cultures

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

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High efficiency plating method for Leishmania promastigotes in semidefined or completely-defined medium

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https://pubmed.ncbi.nlm.nih.gov/24277328

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12 December 2020

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Identifiers

DOI

10.1023/A:1016365128531

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24277328

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277328%20AND%20SRC:MED&resulttype=core&format=json

retrieved

1 March 2020

PubMed publication ID

24277328

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24277328

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24277328%20AND%20SRC:MED&resulttype=core&format=json

retrieved

1 March 2020

 

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