The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6 (Q84596461)

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scientific article published on 27 July 2010

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English	The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6	scientific article published on 27 July 2010

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8 February 2020

The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6 (English)

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8 February 2020

Dmitri Pchejetski

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8 February 2020

Stuart M Pitson

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8 February 2020

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Joao Nunes

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8 February 2020

Karen Coughlan

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8 February 2020

Harjinder Lall

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8 February 2020

Jonathan Waxman

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8 February 2020

Vadim V Sumbayev

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27 July 2010

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8 February 2020

Immunology & Cell Biology

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8 February 2020

89

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8 February 2020

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8 February 2020

268-274

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8 February 2020

Inferences, questions and possibilities in Toll-like receptor signalling

1 reference

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7 January 2021

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Toll-like receptor control of the adaptive immune responses

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Innate immunity

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The role of HIF-1alpha in myeloid cell inflammation

1 reference

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Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis

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7 January 2021

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LPS-induced Toll-like receptor 4 signalling triggers cross-talk of apoptosis signal-regulating kinase 1 (ASK1) and HIF-1alpha protein

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ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

1 reference

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7 January 2021

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HIF-1alpha protein is an essential factor for protection of myeloid cells against LPS-induced depletion of ATP and apoptosis that supports Toll-like receptor 4-mediated production of IL-6.

1 reference

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The involvement of hypoxia-inducible factor 1 alpha in Toll-like receptor 7/8-mediated inflammatory response

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Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets

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Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

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Sphingosine kinase protects lipopolysaccharide-activated macrophages from apoptosis

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Anaphylatoxin signaling in human neutrophils. A key role for sphingosine kinase

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Sphingosine kinase 1: a new modulator of hypoxia inducible factor 1alpha during hypoxia in human cancer cells.

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Differential regulation of sphingosine kinases 1 and 2 in lung injury

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Antisense knockdown of sphingosine kinase 1 in human macrophages inhibits C5a receptor-dependent signal transduction, Ca2+ signals, enzyme release, cytokine production, and chemotaxis

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PI3 kinase and direct S-nitrosation are involved in down-regulation of apoptosis signal-regulating kinase 1 during LPS-induced Toll-like receptor 4 signalling

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Role of MAP kinase-dependent apoptotic pathway in innate immune responses and viral infection

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Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models

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Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel.

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Molecular cloning and functional characterization of murine sphingosine kinase

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Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

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Identifiers

10.1038/ICB.2010.91

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661259%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661259%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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