A unique mechanism for RNA catalysis: the role of metal cofactors in hairpin ribozyme cleavage (Q73603192)

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5 November 2019

title

A unique mechanism for RNA catalysis: the role of metal cofactors in hairpin ribozyme cleavage (English)

1 reference

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5 November 2019

A. Hampel

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12 November 2024

J. A. Cowan

series ordinal

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12 November 2024

language of work or name

English

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National Center for Biotechnology Information

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12 November 2024

publication date

1 July 1997

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5 November 2019

July 1997

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9263639

full work available at URL

12 November 2024

https://doi.org/10.1016/s1074-5521(97)90323-9

online access status

open access

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https://api.elsevier.com/content/article/PII:S1074552197903239?httpAccept=text/xml

12 November 2024

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DOI

https://api.crossref.org/works/10.1016/S1074-5521(97)90323-9

https://api.elsevier.com/content/article/PII:S1074552197903239?httpAccept=text/plain

12 November 2024

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DOI

https://api.crossref.org/works/10.1016/S1074-5521(97)90323-9

12 November 2024

published in

Chemistry and Biology

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5 November 2019

volume

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5 November 2019

issue

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5 November 2019

page(s)

513-517

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Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain

5 November 2019

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The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

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RNA catalytic properties of the minimum (-)sTRSV sequence

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Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting

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The intervening sequence RNA of Tetrahymena is an enzyme

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The Tetrahymena ribozyme acts like an RNA restriction endonuclease

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A small catalytic oligoribonucleotide

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Self-cleaving catalytic RNA.

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7 January 2021

Inert chromium and cobalt complexes as probes of magnesium-dependent enzymes. Evaluation of the mechanistic role of the essential metal cofactor in Escherichia coli exonuclease III.

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Sequence selective coordination of Mg2+(aq) to DNA

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Structural basis for stabilization of Z-DNA by cobalt hexaammine and magnesium cations

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Ionic requirements for RNA binding, cleavage, and ligation by the hairpin ribozyme

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Metal coordination sites that contribute to structure and catalysis in the group I intron from Tetrahymena

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7 January 2021

Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding

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7 January 2021

Role of divalent metal ions in the hammerhead RNA cleavage reaction

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7 January 2021

Nuclear magnetic resonance studies of the hammerhead ribozyme domain. Secondary structure formation and magnesium ion dependence

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7 January 2021

Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom

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7 January 2021

Metal ion catalysis in the Tetrahymena ribozyme reaction

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7 January 2021

Effects of substrate structure on the kinetics of circle opening reactions of the self-splicing intervening sequence from Tetrahymena thermophila: evidence for substrate and Mg2+ binding interactions

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7 January 2021

Binding and cleavage of nucleic acids by the "hairpin" ribozyme

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7 January 2021

'Hairpin' catalytic RNA model: evidence for helices and sequence requirement for substrate RNA.

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7 January 2021

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

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7 January 2021

Mutagenesis of the hairpin ribozyme

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7 January 2021

A general two-metal-ion mechanism for catalytic RNA

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Mechanism of metal-promoted catalysis of nucleic acid hydrolysis by Escherichia coli ribonuclease H

12 November 2024

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Metallobiochemistry of a ribosomal RNA. A possible role for Na+ and K+ in the regulation of Mg2+ binding sites on Escherichia coli 5S rRNA: implications for activity

12 November 2024

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12 November 2024

Identifiers

DOI

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5 November 2019

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