Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein. Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein (Q73575373)

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scientific article published on 01 August 1997

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English	Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein. Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein	scientific article published on 01 August 1997

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252352%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein. Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252352%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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F Benoist

1

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5 November 2019

T Grand-Perret

2

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1 August 1997

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5 November 2019

Journal of Biological Chemistry

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5 November 2019

272

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5 November 2019

33

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5 November 2019

20435-20442

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5 November 2019

Purification and characterization of microsomal triglyceride and cholesteryl ester transfer protein from bovine liver microsomes

1 reference

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21 January 2018

Microsomal triglyceride transfer protein. Specificity of lipid binding and transport

1 reference

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Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability

1 reference

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21 January 2018

Interactions between microsomal triglyceride transfer protein and apolipoprotein B within the endoplasmic reticulum in a heterologous expression system.

1 reference

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21 January 2018

Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia

1 reference

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21 January 2018

Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia

1 reference

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21 January 2018

Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein

1 reference

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21 January 2018

A 30-amino acid truncation of the microsomal triglyceride transfer protein large subunit disrupts its interaction with protein disulfide-isomerase and causes abetalipoproteinemia

1 reference

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21 January 2018

Brefeldin A reversibly inhibits the assembly of apoB containing lipoproteins in McA-RH7777 cells

1 reference

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21 January 2018

Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step

1 reference

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21 January 2018

The amino terminus of apolipoprotein B is necessary but not sufficient for microsomal triglyceride transfer protein responsiveness

1 reference

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21 January 2018

Cotranslocational insertion of apolipoprotein B into the inner leaflet of the endoplasmic reticulum

1 reference

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21 January 2018

Pause transfer: a topogenic sequence in apolipoprotein B mediates stopping and restarting of translocation

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New variation on the translocation of proteins during early biogenesis of apolipoprotein B.

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Apolipoprotein B sequence requirements for hepatic very low density lipoprotein assembly. Evidence that hydrophobic sequences within apolipoprotein B48 mediate lipid recruitment

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Oleic acid stimulation of apolipoprotein B secretion from HepG2 and Caco-2 cells occurs post-transcriptionally

1 reference

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21 January 2018

Butyrate stimulates the secretion of apolipoprotein (apo) A-I and apo B100 by the human hepatoma cell line Hep G2. Induction of apo A-I mRNA with no change of apo B100 mRNA.

1 reference

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21 January 2018

ApoB-100 secretion by HepG2 cells is regulated by the rate of triglyceride biosynthesis but not by intracellular lipid pools

1 reference

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21 January 2018

Influence of triacylglycerol biosynthesis rate on the assembly of apoB-100-containing lipoproteins in Hep G2 cells

1 reference

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21 January 2018

Control of Hep G2-cell triacylglycerol and apolipoprotein B synthesis and secretion by polyunsaturated non-esterified fatty acids and insulin

1 reference

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21 January 2018

Extracellular fatty acids are not utilized directly for the synthesis of very-low-density lipoprotein in primary cultures of rat hepatocytes

1 reference

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21 January 2018

Translocation of apolipoprotein B across the endoplasmic reticulum is blocked in a nonhepatic cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.33.20435

21 January 2018

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

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21 January 2018

Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins

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21 January 2018

Cotranslational inhibition of apoB-100 synthesis by cyclosporin A in the human hepatoma cell line HepG2.

1 reference

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21 January 2018

Intracellular degradation in the regulation of secretion of apolipoprotein B-100 by rabbit hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.33.20435

21 January 2018

Microsomal triacylglycerol transfer protein prevents presecretory degradation of apolipoprotein B-100. A dithiothreitol-sensitive protease is involved

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.33.20435

21 January 2018

Demonstration of a physical interaction between microsomal triglyceride transfer protein and apolipoprotein B during the assembly of ApoB-containing lipoproteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.33.20435

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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21 January 2018

Purification of a calcium-activated neutral proteinase from human placenta

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21 January 2018

L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

1 reference

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21 January 2018

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

1 reference

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21 January 2018

Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells

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Use of the Bidirectional Glenn Procedure in the Presence of Forward Flow From the Ventricles to the Pulmonary Arteries

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The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

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Degradation process of ligand-stimulated platelet-derived growth factor beta-receptor involves ubiquitin-proteasome proteolytic pathway

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HslV-HslU: A novel ATP-dependent protease complex in Escherichia coli related to the eukaryotic proteasome

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Proteolysis, proteasomes and antigen presentation

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The ubiquitin system for protein degradation

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Ubiquitin-proteasome pathway mediates intracellular degradation of apolipoprotein B

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Subpopulations of proteasomes in rat liver nuclei, microsomes and cytosol

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In HepG2 cells, translocation, not degradation, determines the fate of the de novo synthesized apolipoprotein B.

1 reference

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21 January 2018

Apoprotein B100, an inefficiently translocated secretory protein, is bound to the cytosolic chaperone, heat shock protein 70

1 reference

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21 January 2018

apoB-100 has a pentapartite structure composed of three amphipathic alpha-helical domains alternating with two amphipathic beta-strand domains. Detection by the computer program LOCATE.

1 reference

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21 January 2018

Structure of apolipoprotein B-100 of human low density lipoproteins

1 reference

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Expression, secretion, and lipid-binding characterization of the N-terminal 17% of apolipoprotein B

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Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

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Identifiers

10.1074/JBC.272.33.20435

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252352%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9252352%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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