Proteasome involvement and accumulation of ubiquitinated proteins in cerebellar granule neurons undergoing apoptosis (Q73347998)

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3 November 2019

title

Proteasome involvement and accumulation of ubiquitinated proteins in cerebellar granule neurons undergoing apoptosis (English)

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3 November 2019

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N Canu

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3 November 2019

C Barbato

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3 November 2019

M T Ciotti

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3 November 2019

A Serafino

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3 November 2019

L Dus

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3 November 2019

P Calissano

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3 November 2019

publication date

1 January 2000

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3 November 2019

published in

Journal of Neuroscience

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3 November 2019

volume

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3 November 2019

issue

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3 November 2019

page(s)

589-599

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MHC-linked LMP gene products specifically alter peptidase activities of the proteasome

3 November 2019

cites work

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The ubiquitin pathway in Parkinson's disease

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The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

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Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis

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Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species.

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Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival

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The ubiquitin-proteasome proteolytic pathway

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Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis

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Immunohistochemical evidence for apoptosis in Alzheimerʼs disease

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Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice

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Removal of proteasomes from the nucleus and their accumulation in apoptotic blebs during programmed cell death

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Biochemical and temporal analysis of events associated with apoptosis induced by lowering the extracellular potassium concentration in mouse cerebellar granule neurons.

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Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases

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The multicatalytic proteinase complex, a major extralysosomal proteolytic system

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Disruption of the intracellular sulfhydryl homeostasis by cadmium-induced oxidative stress leads to protein thiolation and ubiquitination in neuronal cells

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12 December 2020

Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.

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12 December 2020

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

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12 December 2020

Caspases: the executioners of apoptosis

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12 December 2020

Activation of caspase-3 and apoptosis in cerebellar granule cells

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A new inhibitor of the chymotrypsin-like activity of the multicatalytic proteinase complex (20S proteasome) induces accumulation of ubiquitin-protein conjugates in a neuronal cell.

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12 December 2020

Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments

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Proteasome inhibitors: valuable new tools for cell biologists

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12 December 2020

Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures

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12 December 2020

Purification of two high molecular weight proteases from rabbit reticulocyte lysate

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Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

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Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

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12 December 2020

A ubiquitin C-terminal isopeptidase that acts on polyubiquitin chains. Role in protein degradation

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12 December 2020

The ubiquitin-conjugation system

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12 December 2020

Evidence for apoptotic cell death in Alzheimer's disease.

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12 December 2020

Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes

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12 December 2020

The Role of CED-3-Related Cysteine Proteases in Apoptosis of Cerebellar Granule Cells

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12 December 2020

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

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12 December 2020

Proteasomes: protein degradation machines of the cell

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12 December 2020

Kinetic studies of isopeptidase T: modulation of peptidase activity by ubiquitin

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12 December 2020

Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis

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12 December 2020

Mechanisms and genes of cellular suicide

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12 December 2020

Ubiquitin in neurodegenerative diseases

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12 December 2020

Ubiquitin, proteasomes, and the regulation of intracellular protein degradation

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12 December 2020

Identification of an interleukin-1 beta converting enzyme-like activity that increases upon treatment of P19 cells with retinoic acid as the proteasome

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12 December 2020

Early release and subsequent caspase-mediated degradation of cytochrome c in apoptotic cerebellar granule cells

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12 December 2020

Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis

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12 December 2020

Inhibition of etoposide-induced apoptosis with peptide aldehyde inhibitors of proteasome

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12 December 2020

Apoptosis in the pathogenesis and treatment of disease

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12 December 2020

In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome

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12 December 2020

Multicatalytic endopeptidase complex: proteasome

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12 December 2020

Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis

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12 December 2020

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

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12 December 2020

Proteasome activation occurs at an early, premitochondrial step of thymocyte apoptosis.

1 reference

12 December 2020

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains

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12 December 2020

An automated colorimetric microassay for neuronotrophic factors

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12 December 2020

The role of estrogens on the proliferation of human breast tumor cells (MCF-7).

1 reference

12 December 2020

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

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12 December 2020

Changes in proteasome activity following transient ischemia

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12 December 2020

Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells

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12 December 2020

The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene

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12 December 2020

Proteasomes play an essential role in thymocyte apoptosis

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12 December 2020

Activation of the cell death program by inhibition of proteasome function

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12 December 2020

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

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12 December 2020

Development of a method for measuring cell number: Application to CNS primary neuronal cultures

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12 December 2020

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

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12 December 2020

Proteasome activities decrease during dexamethasone-induced apoptosis of thymocytes

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12 December 2020

Regulation of ubiquitin‐dependent processes by deubiquitinating enzymes

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12 December 2020

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

1 reference

12 December 2020

10.1523/JNEUROSCI.20-02-00589.2000

Identifiers

DOI

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3 November 2019

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3 November 2019

PubMed publication ID

10632588

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