2-mercaptoethanol restores the ability of nuclear factor kappa B (NF kappa B) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Evidence for oxidation of glutathione in the mechanism (Q72997489)

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scientific article published on 01 December 1996

Language	Label	Description	Also known as
English	2-mercaptoethanol restores the ability of nuclear factor kappa B (NF kappa B) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Evidence for oxidation of glutathione in the mechanism	scientific article published on 01 December 1996

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9003388%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

2-mercaptoethanol restores the ability of nuclear factor kappa B (NF kappa B) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Evidence for oxidation of glutathione in the mechanism of inhibition of NF kappa B by PDTC (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9003388%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference

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inferred from title

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author name string

P Brennan

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9003388%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

L A O'Neill

2

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Europe PubMed Central

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31 October 2019

publication date

1 December 1996

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31 October 2019

number of pages

7

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Biochemical Journal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9003388%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

320 ( Pt 3)

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Europe PubMed Central

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31 October 2019

975-981

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9003388%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-κB

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Covalent cross-linking of proteins by carbon disulfide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-lipoic acid is a potent inhibitor of NF-kappa B activation in human T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of cysteine62 in DNA recognition by the P50 subunit of NF-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic degradation of MAD3 (I kappa B alpha) and enhanced processing of the NF-kappa B precursor p105 are obligatory steps in the activation of NF-kappa B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct effects of glutathione disulphide on the nuclear transcription factor kappa B and the activator protein-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function and activation of NF-kappa B in the immune system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of oxidants and antioxidants on nuclear factor kappa B activation in three different cell lines: evidence against a universal hypothesis involving oxygen radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of reactive oxygen intermediates in osteoclastic bone resorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Towards an understanding of the signal transduction pathways for interleukin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of inducible nitric oxide synthase expression in rat mesangial cells and isolated glomeruli

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyrrolidine dithiocarbamate prevents IL-1-induced nitric oxide synthase mRNA, but not superoxide dismutase mRNA, in insulin producing cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dithiocarbamates Induce Apoptosis in Thymocytes by Raising the Intracellular Level of Redox-active Copper

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies into the effect of the tyrosine kinase inhibitor herbimycin A on NF-kappa B activation in T lymphocytes. Evidence for covalent modification of the p50 subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of NF kappa B activation by interleukin-1 and tumour necrosis factor in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of NF kappa B activity by oxidative processes in intact cells mechanism of action of pyrolidine dithiocarbamate and diamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/9003388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3200975

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9003388%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9003388%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9003388%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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