Concentration and timing dependence of lethality enhancement between topotecan, a topoisomerase I inhibitor, and ionizing radiation (Q71727512)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8892461%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

title

Concentration and timing dependence of lethality enhancement between topotecan, a topoisomerase I inhibitor, and ionizing radiation (English)

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20 October 2019

J P Lamond

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20 October 2019

M Wang

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20 October 2019

T J Kinsella

series ordinal

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20 October 2019

D A Boothman

series ordinal

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20 October 2019

language of work or name

English

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publication date

1 September 1996

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International Journal of Radiation Oncology Biology Physics

20 October 2019

published in

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20 October 2019

volume

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20 October 2019

issue

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20 October 2019

page(s)

361-368

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Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks

20 October 2019

cites work

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Anticarcinogenic potential of DNA-repair modulators

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Interaction of topoisomerase I inhibitors with radiation in cis-diamminedichloroplatinum(II)-sensitive and -resistant cells in vitro and in the FSAIIC fibrosarcoma in vivo

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7 January 2021

Activity of topotecan, a new topoisomerase I inhibitor, against human tumor colony-forming units in vitro

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7 January 2021

Apoptotic cell death triggered by camptothecin or teniposide. The cell cycle specificity and effects of ionizing radiation

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7 January 2021

DNA damaging and cell cycle effects of the topoisomerase I poison camptothecin in irradiated human cells

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7 January 2021

DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts

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7 January 2021

On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

1 reference

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7 January 2021

Potentiation of radiation response in human carcinoma cells in vitro and murine fibrosarcoma in vivo by topotecan, an inhibitor of DNA topoisomerase I

1 reference

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7 January 2021

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

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7 January 2021

The inhibition of cellular recovery in human tumour cells by inhibitors of topoisomerase

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7 January 2021

Phase I and pharmacologic study of topotecan: a novel topoisomerase I inhibitor

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7 January 2021

The current status of camptothecin analogues as antitumor agents

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7 January 2021

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

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7 January 2021

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1 reference

7 January 2021

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Identifiers

DOI

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20 October 2019

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