The role of the 5-HT2A and 5-HT2C receptors in the stimulus effects of hallucinogenic drugs. III: The mechanistic basis for supersensitivity to the LSD stimulus following serotonin depletion (Q70959230)

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scientific article published on 01 October 1995

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English	The role of the 5-HT2A and 5-HT2C receptors in the stimulus effects of hallucinogenic drugs. III: The mechanistic basis for supersensitivity to the LSD stimulus following serotonin depletion	scientific article published on 01 October 1995

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scholarly article

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15 October 2019

The role of the 5-HT2A and 5-HT2C receptors in the stimulus effects of hallucinogenic drugs. III: The mechanistic basis for supersensitivity to the LSD stimulus following serotonin depletion (English)

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15 October 2019

lysergic acid diethylamide

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Daniel S Lorrain

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object named as

D S Lorrain

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15 October 2019

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D Fiorella

1

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15 October 2019

S Helsley

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15 October 2019

R A Rabin

4

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15 October 2019

J C Winter

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15 October 2019

publication date

1 October 1995

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15 October 2019

Psychopharmacology

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15 October 2019

121

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15 October 2019

3

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15 October 2019

364-372

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15 October 2019

Depletion of brain serotonin differently affects behaviors induced by 5HT1A, 5HT1C, and 5HT2 receptor activation in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

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5,7-Dihydroxytryptamine: improvement of its selectivity for serotonin neurons in the CNS by pretreatment with desipramine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

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Discriminative stimulus properties of 8-OH-DPAT in rats are not altered by pretreatment with para-chlorophenylalanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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Tryptophan hydroxylase inhibition: the mechanism by which p-chlorophenylalanine depletes rat brain serotonin

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https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

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p -Chloroamphetamine: Selective Neurotoxic Action in Brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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Antagonism of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane stimulus with a newly identified 5-HT2- versus 5-HT1C-selective antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanistic studies on DOM as a discriminative stimulus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in the behavioral effects of LSD by motivational and neurohumoral variables

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Denervation supersensitivity of 5-HT-1c receptors in rat choroid plexus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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Gaps and peculiarities in 5-HT2 receptor studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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Nicotine as a discriminative stimulus in rats depleted of norepinephrine or 5-hydroxytryptamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the effects of 5,7-dihydroxytryptamine on serotonin and catecholamine neurons in the rat CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analyzing mechanism(s) of hallucinogenic drug action with drug discrimination procedures

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple populations of serotonin receptors may modulate the behavioral effects of serotonergic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of 5-HT2C receptors in mediating the discriminative stimulus properties of m-chlorophenylpiperazine (mCPP)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug discrimination in rats: The effects of phencyclidine and ditran

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the 5-HT2A and 5-HT2C receptors in the stimulus effects ofm-chlorophenylpiperazine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of tryptophan hydroxylase activity and 5-hydroxytryptamine concentration in certain rat brain nuclei after p-chloroamphetamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin receptors and their ligands: a lack of selective agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The concept of selectivity in 5-HT receptor research

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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The stimulus effects of serotonergic hallucinogens in animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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Selective destruction of the serotonergic fibers of the fornix-fimbria and cingulum bundle increases 5-HT1 but not 5-HT2 receptors in rat midbrain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of 5-HT2A and 5-HT2C receptors in the stimulus effects of hallucinogenic drugs. II: Reassessment of LSD false positives.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discriminative stimulus properties of m-chlorophenylpiperazine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Hydroxytryptamine depletion in mesencephalic nuclei of rat brain following a single injection of p-chloroamphetamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysergic acid diethylamide and 2,5-dimethoxy-4-methylamphetamine are partial agonists at serotonin receptors linked to phosphoinositide hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term biochemical and behavioral effects of p-chloroamphetamine in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of serotonin-stimulated phosphoinositide hydrolysis: relation to the serotonin 5-HT-2 binding site.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive antagonism by recognized 5-HT2 receptor antagonists at 5-HT1C receptors in pig choroid plexus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radioligand binding evidence implicates the brain 5-HT2 receptor as a site of action for LSD and phenylisopropylamine hallucinogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysergic Acid Diethylamide: Sensitive Neuronal Units in the Midbrain Raphe

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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The effect of serotonin depletion on the discriminability of LSD.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p-Chlorophenylalanine: a specific depletor of brain serotonin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(+)Lysergic acid diethylamide, but not its nonhallucinogenic congeners, is a potent serotonin 5HT1C receptor agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accentuation of the psychological effects of LSD-25 in normal subjects treated with reserpine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of serotonin depletion by p-chlorophenylalanine upon discriminative behaviours

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the 5-HT2A and 5-HT2C receptors in the stimulus effects of hallucinogenic drugs. I: Antagonist correlation analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple serotonin receptors: Regional distribution and effect of raphe lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine on locomotor activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral sensitivity to LSD: Dependency upon the pattern of central 5HT depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1 receptors and behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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Sensitivity to psychoactive drugs and the serotonergic neuronal system

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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A behavioral and pharmacological analysis of some discriminable properties of d-LSD in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of LSD-25 on brain serotonin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of serotonin in the discriminative stimulus properties of mescaline

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of manipulation of presynaptic 5-HT nerve terminals on postsynaptic 5-HT1 and 5-HT2 binding sites of the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The time-dependent stimulus effects of R(-)-2,5-dimethoxy-4-methamphetamine (DOM): implications for drug-induced stimulus control as a method for the study of hallucinogenic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the 'atypical' antipsychotics, clozapine and risperidone

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHEMICALLY-INDUCED ALTERATIONS IN THE BEHAVIORAL EFFECTS OF LSD-25.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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Narcotic cue and narcotic state: Differential involvement of brain 5-hydroxytryptamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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Classical hallucinogens: an introductory overview.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

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Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in the behavioral effects of LSD by pretreatment with p-chlorophenylalanine and ?-methyl-p-tyrosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5,7-Dihydroxytryptamine as a tool to study the functional role of central 5-hydroxytryptamine neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal 5,7-DHT lesions upregulate [3H]mesulergine-labelled spinal 5-HT1C binding sites in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do classical hallucinogens act as 5-HT2 agonists or antagonists?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide increases dopamine and serotonin release in the medial preoptic area

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of serotonin neurotoxins in discrete brain nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Putative selective 5-HT-2 antagonists block serotonin 5-HT-1c receptors in the choroid plexus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8584619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF02246076

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8584619%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8584619%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

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