Essential roles of IL-12 and dendritic cells but not IL-23 and macrophages in lupus-like diseases initiated by cell surface HSP gp96 (Q79760223)

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25 December 2019

title

Essential roles of IL-12 and dendritic cells but not IL-23 and macrophages in lupus-like diseases initiated by cell surface HSP gp96 (English)

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25 December 2019

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Jie Dai

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25 December 2019

Bei Liu

series ordinal

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25 December 2019

Daniel J Cua

series ordinal

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25 December 2019

Zihai Li

series ordinal

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25 December 2019

publication date

1 March 2007

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European Journal of Immunology

25 December 2019

published in

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25 December 2019

volume

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25 December 2019

issue

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25 December 2019

page(s)

706-715

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Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

25 December 2019

cites work

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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Transforming growth factor-beta induces development of the T(H)17 lineage

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

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7 January 2021

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

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Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases

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Immunotherapy of Tumors with Autologous Tumor-Derived Heat Shock Protein Preparations

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TLR4 up-regulation at protein or gene level is pathogenic for lupus-like autoimmune disease

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7 January 2021

Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus

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Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event

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Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription

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Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells

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Roles of heat-shock proteins in innate and adaptive immunity

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In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

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Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells

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Pulmonary immunity to Listeria is enhanced by elimination of alveolar macrophages

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7 January 2021

Roles of macrophages in measles virus infection of genetically modified mice

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7 January 2021

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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7 January 2021

IL-12- and IL-23-induced T helper cell subsets: birds of the same feather flock together

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7 January 2021

IL-12 deficiency in MRL-Fas(lpr) mice delays nephritis and intrarenal IFN-gamma expression, and diminishes systemic pathology

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7 January 2021

IL-12 and IL-23: master regulators of innate and adaptive immunity.

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7 January 2021

Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection

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7 January 2021

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

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7 January 2021

Macrophage receptors and immune recognition

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7 January 2021

Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo

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7 January 2021

Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells.

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7 January 2021

Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate

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7 January 2021

Cellular requirements for tumor-specific immunity elicited by heat shock proteins: tumor rejection antigen gp96 primes CD8+ T cells in vivo

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7 January 2021

Dendritic cell apoptosis in the maintenance of immune tolerance

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7 January 2021

Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity

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7 January 2021

Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

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7 January 2021

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

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7 January 2021

Dendritic cells maximize the memory CD8 T cell response to infection

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7 January 2021

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

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7 January 2021

Identifiers

DOI

10.1002/EJI.200636643

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17294405%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17294405%20AND%20SRC:MED&resulttype=core&format=json